Used 2021 Mercedes-Benz S-Class for Sale near Phoenix, AZ
144 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 143 currently listed for sale near Phoenix, AZ and an average price of $67,696.00, 33.6% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
94.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a new sophisticated infotainment system, enhanced powertrains, and standard all-wheel drive (AWD) for optimal performance.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 143 currently listed for sale near Phoenix, AZ and an average price of $67,696.00, 33.6% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars.
94.4% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a new sophisticated infotainment system, enhanced powertrains, and standard all-wheel drive (AWD) for optimal performance.
Why it stands out
The 2021 Mercedes-Benz S-Class stands out in the luxury sedan segment with its combination of technology, performance, and comfort. The redesigned model showcases a more sophisticated infotainment system alongside new powertrains that include a 3.0-liter inline-six in the S500 and a potent 4.0-liter twin-turbo V8 in the S580, delivering impressive power and hybrid efficiency. Interior enhancements, such as a minimalist design and ambient lighting with 64 color options, contribute to a luxurious driving experience. While its high price point reflects its status, the S-Class offers numerous features that cater to buyers seeking cutting-edge technology and superior comfort. Expert reviews commend the exceptional handling and ride quality, making it an appealing choice for those in the luxury market.
Other model years to consider
- Average price: $81,321.00
- Good/great deal percentage: 26.1%
- Total listings: 230
- Average price: $86,490.00
- Good/great deal percentage: 28.6%
- User rating: 4.5 / 5
- Total listings: 203
- Average price: $22,608.00
- Good/great deal percentage: 29.6%
- User rating: 5 / 5
- Total listings: 125
This analysis is based on CarGurus' proprietary market data from May 26, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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