Used 2021 Mercedes-Benz S-Class for Sale near Phoenix, AZ
144 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 137 currently listed for sale near Phoenix, AZ and an average price of $64,449.00, 24.1% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.7% of 2021 S-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz S-Class comes with a luxurious design, advanced technology features, and a powerful engine lineup, including both a six-cylinder and a V8 option.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 137 currently listed for sale near Phoenix, AZ and an average price of $64,449.00, 24.1% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.7% of 2021 S-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz S-Class comes with a luxurious design, advanced technology features, and a powerful engine lineup, including both a six-cylinder and a V8 option.
Why it stands out
The 2021 Mercedes-Benz S-Class continues its legacy as a flagship luxury sedan offering unmatched sophistication and cutting-edge technology. With a fresh overhaul, this generation includes a more sophisticated infotainment system, enhanced powertrains with electric-assist technology, and aerodynamic improvements like a drag coefficient that rivals that of more fuel-efficient cars. The S-Class offers two potent engine options: a 429-horsepower inline-six in the S500 and a 496-horsepower V8 in the S580, both equipped with advanced all-wheel drive and a mild-hybrid system for improved efficiency. Owners report an impressive feeling of comfort and refinement, with praise for its handling and acceleration. Notably, the revised design offers more interior space while maintaining the high-quality materials expected from Mercedes, making it a desirable choice for those looking for elegance, performance, and state-of-the-art safety features.
Other model years to consider
- Average price: $74,726.00
- Good/great deal percentage: 19.8%
- User rating: 4.8 / 5
- Total listings: 192
- Average price: $27,234.00
- Good/great deal percentage: 13.0%
- User rating: 4.88 / 5
- Total listings: 162
- Average price: $75,014.00
- Good/great deal percentage: 20.5%
- User rating: 4.2 / 5
- Total listings: 215
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
See more price trends
