Used 2021 Mercedes-Benz S-Class for Sale near Phoenix, AZ
137 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 133 currently listed for sale near Phoenix, AZ and an average price of $64,687.00, 18.0% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
85.7% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a sophisticated infotainment system, exceptional performance with two powerful engine options, and luxurious interior amenities that set a high standard for luxury sedans.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 133 currently listed for sale near Phoenix, AZ and an average price of $64,687.00, 18.0% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
85.7% of 2021 S-Class models on CarGurus are accident free.
The 2021 Mercedes-Benz S-Class features a sophisticated infotainment system, exceptional performance with two powerful engine options, and luxurious interior amenities that set a high standard for luxury sedans.
Why it stands out
The 2021 Mercedes-Benz S-Class stands out in the premium sedan segment due to its advanced technology and incredible performance. With a complete redesign, this flagship model enhances its reputation as a technological showcase for Mercedes-Benz, offering features like the updated MBUX infotainment system and a high-definition digital display. The S-Class is available with two configurations: the S500, powered by a turbocharged inline-six engine, and the more robust S580, which boasts a twin-turbo V8 engine. Both options deliver impressive acceleration and a smooth ride, aided by the available air suspension and rear-wheel steering. Beyond its performance, the vehicle's luxurious interiors are filled with high-quality materials and exceptional comfort features, including massage seats and customizable ambient lighting. While the S-Class holds a high price tag, it remains a top choice for buyers seeking unmatched luxury and advanced capabilities in their driving experience.
Other model years to consider
- Average price: $74,556.00
- Good/great deal percentage: 16.5%
- User rating: 4.8 / 5
- Total listings: 182
- Average price: $25,080.00
- Good/great deal percentage: 10.3%
- User rating: 4.88 / 5
- Total listings: 155
- Average price: $39,800.00
- Good/great deal percentage: 20.2%
- User rating: 4.86 / 5
- Total listings: 119
This analysis is based on CarGurus' proprietary market data from March 31, 2026, CarGurus experts' opinions, and generative AI.
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Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
James B
Reviewed a 2021 Mercedes-Benz S 580 Sedan 4MATIC on Oct 14, 2024
The car is loaded with luxuries , very stylish at the same time sporty. You get a lot of car for the money and they hold there value. BMW would be close cusin to Mercedes.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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