Used 2021 Mercedes-Benz S-Class for Sale nearMiami, FL
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Leather
- Transmission:
- 9-Speed Automatic
- Mileage:
- 12,613
- Stock #:
- TPC036
- VIN:
- W1K6G7GB4NA151050
Sponsored by The Platinum Collection
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
12,613 mi
$71,979
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 621 hp 6L V12
- Exterior color:
- Black
- Combined gas mileage:
- 17 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 43,078
- Stock #:
- 8G47341A
- VIN:
- W1KUX8ABXLA563797
Sponsored Listing
2020 Mercedes-Benz S-Class
Maybach S 650 Sedan RWD
43,078 mi
$76,487
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 19 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 13,614
- Stock #:
- NA112671
- VIN:
- W1K6X7GB6NA112671
Sponsored Listing
2022 Mercedes-Benz S-Class
Maybach S 580 4MATIC AWD
13,614 mi
$131,493
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 26,716
- Stock #:
- P162296
- VIN:
- W1K6G7GB3NA162296
-$10,950
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
26,716 mi
$77,394
$66,444
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 3L V6
- Exterior color:
- Diamond White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Sahara Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 41,230
- Stock #:
- LA529420
- VIN:
- W1KUG6GB8LA529420
2020 Mercedes-Benz S-Class
S 450 Sedan RWD
41,230 mi
$37,448
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 5,969
- Stock #:
- L5115W
- VIN:
- W1K6G7GB7NA163466
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
5,969 mi
$75,333
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 469 hp 3L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 65 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,964
- Stock #:
- L2395202
- VIN:
- W1KUG7DB1LA529608
2020 Mercedes-Benz S-Class
S 560e Sedan RWD
30,964 mi
$41,396
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 621 hp 6L V12
- Exterior color:
- Black
- Combined gas mileage:
- 17 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 43,078
- Stock #:
- 8G47341A
- VIN:
- W1KUX8ABXLA563797
2020 Mercedes-Benz S-Class
Maybach S 650 Sedan RWD
43,078 mi
$76,487
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,029
- Stock #:
- 143767
- VIN:
- W1K6G7GB9NA143767
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
25,029 mi
$74,950
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Obsidian Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Sienna Brown/Black
- Transmission:
- Automatic
- Mileage:
- 43,784
- Stock #:
- NA118845
- VIN:
- W1K6G7GBXNA118845
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
43,784 mi
$68,895
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Sahara Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,965
- Stock #:
- P2462M
- VIN:
- W1KUG8GB5LA556196
2020 Mercedes-Benz S-Class
S 560 4MATIC Sedan AWD
46,965 mi
$44,597
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 33,628
- Stock #:
- A158768
- VIN:
- W1K6G6DB0NA158768
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
33,628 mi
$54,545
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 8,962
- Stock #:
- UP8238
- VIN:
- W1K6G7GB1NA161535
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
8,962 mi
$69,718
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 157 currently listed for sale near Miami, FL and an average price of $70,302.00, 31.8% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars and CarGurus experts gave it a 7.5 / 10.
85.4% of 2021 S-Class models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 37,858
- Stock #:
- S71326K
- VIN:
- W1K6G7GB9MA045126
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
37,858 mi
$62,899
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 46,650
- Stock #:
- NA164674
- VIN:
- W1K6G6DBXNA164674
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
46,650 mi
$56,990
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 57,215
- Stock #:
- LA560180
- VIN:
- W1KUG8DB4LA560180
2020 Mercedes-Benz S-Class
S 560 Sedan RWD
57,215 mi
$41,795
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,906
- Stock #:
- I357708A
- VIN:
- W1K6G7GB6MA036142
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
38,906 mi
$61,225
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Diamond White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 53,189
- Stock #:
- L5086
- VIN:
- W1K6G7GB7MA026333
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
53,189 mi
$59,739
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Coupe
- Doors:
- 2 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 463 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 33,977
- Stock #:
- LA040732
- VIN:
- WDDXJ8GB0LA040732
2020 Mercedes-Benz S-Class
S 560 4MATIC Coupe AWD
33,977 mi
$61,990
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 37,718
- Stock #:
- 084498
- VIN:
- W1K6G6DBXNA084498
2022 Mercedes-Benz S-Class
S 500 4MATIC AWD
37,718 mi
$60,190
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Green (Manufaktur Olive)
- Combined gas mileage:
- 19 MPG
- Fuel type:
- Gasoline
- Interior color:
- Exclusive Maybach Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 19,879
- Stock #:
- 7297
- VIN:
- W1K6X7GB9NA055110
2022 Mercedes-Benz S-Class
Maybach S 580 4MATIC AWD
19,879 mi
$121,399
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Nappa
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,093
- Stock #:
- P19333
- VIN:
- W1K6G7GB8MA028608
2021 Mercedes-Benz S-Class
S 580 Sedan 4MATIC
49,093 mi
$58,238
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- S-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 496 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 26,716
- Stock #:
- P162296
- VIN:
- W1K6G7GB3NA162296
-$10,950
Sponsored Listing
2022 Mercedes-Benz S-Class
S 580 4MATIC AWD
26,716 mi
$77,394
$66,444
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 157 currently listed for sale near Miami, FL and an average price of $70,302.00, 31.8% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 4 / 5 stars and CarGurus experts gave it a 7.5 / 10.
85.4% of 2021 S-Class models on CarGurus are accident free.
Why it stands out
Mercedes gives its flagship an overhaul, and the 2021 Mercedes-Benz S-Class is built to reinforce exactly why the nameplate sits at the top of the brand’s hierarchy. It has long served as a technological showcase, and Mercedes has used the redesigned sedan to introduce innovations that eventually trickled down to mainstream vehicles. For buyers, that means the appeal is not just prestige, but also the sense that the car is meant to showcase the latest thinking in luxury, comfort, and technology.
The 2021 S-Class also arrives with a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork. It launches in two configurations, both with 4Matic all-wheel drive and EQ Boost mild-hybrid systems: the S500 4Matic uses a six-cylinder engine, while the S580 4Matic uses a V8. That combination makes the car sound as advanced as it is luxurious, and the available power is a clear strength. The main drawback is straightforward: it carries a high price.
Other model years to consider
- Average price: $93,370.00
- Good/great deal percentage: 34.8%
- Total listings: 310
- Average price: $70,933.00
- Good/great deal percentage: 30.0%
- User rating: 4.5 / 5
- Total listings: 257
- Average price: $28,739.00
- Good/great deal percentage: 15.3%
- User rating: 4.95 / 5
- Total listings: 183
This analysis is based on CarGurus' proprietary market data from August 6, 2026, CarGurus experts' opinions, and generative AI.
4.0 Overall rating
Filter by rating
Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
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