Used 2021 Mercedes-Benz GLS for Sale near Portland, OR
100 results
CarGurus Analysis:
2021 Mercedes-Benz GLS
With 101 currently listed for sale near Portland, OR and an average price of $51,002.00, 14.9% of 2021 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.93 / 5 stars.
105.0% of 2021 GLS models on CarGurus are accident free.
The 2021 Mercedes-Benz GLS combines luxurious comfort with advanced technology, making it a top choice in the full-size SUV segment.
CarGurus Analysis: 2021 Mercedes-Benz GLS
overall

Summary
With 101 currently listed for sale near Portland, OR and an average price of $51,002.00, 14.9% of 2021 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.93 / 5 stars.
105.0% of 2021 GLS models on CarGurus are accident free.
The 2021 Mercedes-Benz GLS combines luxurious comfort with advanced technology, making it a top choice in the full-size SUV segment.
Why it stands out
The 2021 Mercedes-Benz GLS-Class positions itself as the S-Class of SUVs, delivering an unmatched level of luxury and performance. With a spacious interior across three rows of seating, it emphasizes comfort and ease—touting features such as nine USB ports, dual-zone automatic climate control, and premium sound systems. Buyers appreciate the powerful engine options, including a twin-turbocharged 3.0-liter inline-six with 362 horsepower and a robust V8 in higher trims, ensuring strong performance without sacrificing ride quality. The GLS also embraces state-of-the-art technology with the MBUX infotainment system, which includes a massive touch screen and voice controls, offering drivers and passengers an intuitive experience. While it excels in numerous areas, prospective buyers should consider the somewhat cramped third row and the complexities of the technology features that might take some getting used to.
Other model years to consider
- Average price: $67,384.00
- Good/great deal percentage: 20.6%
- User rating: 5 / 5
- Total listings: 131
- Average price: $82,247.00
- Good/great deal percentage: 22.4%
- Total listings: 116
- Average price: $77,624.00
- Good/great deal percentage: 17.3%
- User rating: 5 / 5
- Total listings: 127
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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4.7 Overall rating
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Wilber R
Reviewed a 2021 Mercedes-Benz GLS on Sep 4, 2024
Excellent car, very good finish full of attributes, spacious.
James C
Reviewed a 2021 Mercedes-Benz GLS on Dec 22, 2022
I feel that the features listed for this vehicle is good. I just didnt see one option that would have made me buy the vehicle fast. I did not see the multi contour massage feature. I wished that it would have been made clear on the listing.
Michelle A
Reviewed a 2021 Mercedes-Benz 450 4MATIC on Apr 8, 2023
Very nice ride, drives so well and well built. I love it so far!!
2021 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 450 4MATIC | $76,000 |
| AMG GLS 63 4MATIC AWD | $132,100 |
| 580 4MATIC | $98,850 |
| 600 Mercedes-Maybach 4MATIC | $160,500 |
2021 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz GLS prices has changed over time.
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