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Used 2021 Lexus RX for Sale near South Carolina

168 results
Columbia, SC
2021 Lexus RX 350 FWD Monroe Nissan

2021 Lexus RX

350 FWD

94,241 miles

$27,250

Good Deal
Monroe, NC
75 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
94,241
Stock number:
P4166
VIN:
2T2AZMAA0MC197445

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

65,821 miles

$36,991

Fair Deal
Certified Pre-Owned
Charlotte, NC
81 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
65,821
Stock number:
T19669B
VIN:
2T2HZMAA8MC214667

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

61,559 miles

$33,999

Fair Deal
Anderson, SC
95 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Pewter
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
61,559
Stock number:
12474
VIN:
2T2AZMAA6MC201871

Sponsored

2020 Lexus RX 350L FWD

2020 Lexus RX

350L FWD

40,047 miles

$34,000

Great Deal
Gaffney, SC
84 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
40,047
Stock number:
U3950
VIN:
JTJHZKEA7L2014618

2021 Lexus RX 350 AWD

2021 Lexus RX

350 AWD

51,561 miles

$36,897

Great Deal
Store transfer to Columbia, SC
925 mi away • Price includes $899 shipping Price includes $899 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
51,561
Stock number:
28086139
VIN:
2T2HZMDA2MC259986

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2020 Lexus RX

350 AWD

46,562 miles

$34,998

Great Deal
Charlotte, NC
80 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
46,562
Stock number:
28106314
VIN:
2T2HZMDA1LC253305

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2022 Lexus RX

350 FWD

54,153 miles

$33,471

Great Deal
Lowell, NC
85 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
54,153
Stock number:
PV23479
VIN:
2T2AZMAA4NC223479

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2022 Lexus RX

350 FWD

94,544 miles

$29,698

Great Deal
Charlotte, NC
76 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
94,544
Stock number:
PC6103A
VIN:
2T2HZMAAXNC237949

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2022 Lexus RX

350 FWD

62,994 miles

$37,990

Good Deal
Certified Pre-Owned
Charlotte, NC
94 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
Automatic
Mileage:
62,994
Stock number:
T28538A
VIN:
2T2HZMAA3NC221298

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2021 Lexus RX

350 FWD

58,244 miles

$33,065

Good Deal
Monroe, NC
75 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
58,244
Stock number:
P4247
VIN:
2T2HZMAA3MC193226

Preparing for a close up...

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2021 Lexus RX

350 FWD

94,241 miles

$27,250

Good Deal
Monroe, NC
75 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
94,241
Stock number:
P4166
VIN:
2T2AZMAA0MC197445

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

41,741 miles

$40,997

Good Deal
Store transfer to Columbia, SC
1,765 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
41,741
Stock number:
28004455
VIN:
2T2HZMAA5NC220928

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

42,235 miles

$37,483

Good Deal
Sumter, SC
40 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
42,235
Stock number:
P9915
VIN:
2T2AZMAA1NC228512

Preparing for a close up...

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2022 Lexus RX

350 FWD

28,675 miles

$36,398

Great Deal
Pineville, NC
74 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
28,675
Stock number:
GNC221503
VIN:
2T2AZMAA9NC221503

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2022 Lexus RX

350 FWD

83,164 miles

$33,097

Great Deal
Store transfer to Columbia, SC
1,004 mi away • Price includes $1,099 shipping Price includes $1,099 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
83,164
Stock number:
28310874
VIN:
2T2HZMAA4NC256643

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2022 Lexus RX

350 FWD

39,195 miles

$40,197

Great Deal
Store transfer to Columbia, SC
245 mi away • Price includes $199 shipping Price includes $199 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
Automatic
Mileage:
39,195
Stock number:
28123591
VIN:
2T2HZMAA1NC234308

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2022 Lexus RX

350 FWD

53,445 miles

$37,425

Good Deal
Matthews, NC
77 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
53,445
Stock number:
PL48943
VIN:
2T2HZMAA9NC248943

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2022 Lexus RX

350 F Sport Handling AWD

29,993 miles

$42,369

Great Deal
Concord, NC
97 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
29,993
Stock number:
3N4978A
VIN:
2T2YZMDA1NC354055

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2021 Lexus RX

350 AWD

49,822 miles

$37,491

Fair Deal
Concord, NC
94 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nori Green Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
Automatic
Mileage:
49,822
Stock number:
XH21757A
VIN:
2T2HZMDA0MC277919

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

66,677 miles

$35,800

Fair Deal
Charlotte, NC
78 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
66,677
Stock number:
LR23800
VIN:
2T2AZMAA3NC223800

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / South Carolina
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX ## Summary - With 1,401 currently listed for sale on CarGurus and an **average price of $35,415.00**, 35.1% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Lexus RX 4.73 / 5 stars. - **74.8% of 2021 RX models on CarGurus are accident free**. - The 2021 Lexus RX continues its legacy as a formidable luxury SUV, boasting reliable performance and upscale features, as well as new standard safety systems. ## Why it stands out The 2021 Lexus RX distinguishes itself in the competitive luxury SUV segment with its combination of comfort, reliability, and upscale design. This year's model maintains the sleek aesthetics of previous iterations, featuring a bold front grille, angular headlights, and a sophisticated floating roof design. Enhancements in safety technology are notable, with the inclusion of Lexus Safety System+ 2.0, which offers features like automatic emergency braking and adaptive cruise control. While the RX is acclaimed for its smooth driving experience and ample comfort, some users expressed a desire for improved cargo space and more responsive brakes, indicating a balance between luxury and practicality. ## Other model years to consider - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $46,884.00 - Good/great deal percentage: 32.9% - User rating: 4.62 / 5 - Total listings: 2,464 - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $32,616.00 - Good/great deal percentage: 37.2% - User rating: 4.77 / 5 - Total listings: 1,147 - **[2022 Lexus RX](https://www.cargurus.com/Cars/l-Used-2022-Lexus-RX-c31847)** - Average price: $39,793.00 - Good/great deal percentage: 32.4% - User rating: 4.58 / 5 - Total listings: 2,070 This analysis is based on CarGurus' proprietary market data from February 20, 2026, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in South Carolina?

The average 2021 Lexus RX costs about $35,416.00. The average price has decreased by -3.6% since last year. The 125 for sale near South Carolina on CarGurus, range from $23,998 to $48,998 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in South Carolina have no reported accidents or damage?

114 out of 125 for sale near South Carolina have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

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