Used 2021 Lexus RX for Sale nearNaples, FL
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 85,318
- Stock #:
- CM89626A
- VIN:
- 2T2YZMDA4LC222145


Sponsored by Mazda of Fort Myers
2020 Lexus RX
350 F Sport Performance AWD
85,318 mi
$30,291
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 110,683
- Stock #:
- NC242873C
- VIN:
- 2T2AZMAA4NC242873

-$910
Sponsored Listing
2022 Lexus RX
350 FWD
110,683 mi
$32,328
$31,418
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 58,189
- Stock #:
- LC160849
- VIN:
- 2T2HZMAA8LC160849

Sponsored Listing
2020 Lexus RX
350 FWD
58,189 mi
$31,698
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 83,534
- Stock #:
- C077608A
- VIN:
- 2T2AZMAA7MC199158

2021 Lexus RX
350 FWD
83,534 mi
$30,922
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 88,422
- Stock #:
- LC166340
- VIN:
- 2T2HZMAA0LC166340

-$791
2020 Lexus RX
350 FWD
88,422 mi
$27,783
$26,992
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 37,485
- Stock #:
- LC16843A
- VIN:
- 2T2HZMAA6LC168433

2020 Lexus RX
350 FWD
37,485 mi
$36,642
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,280
- Stock #:
- MC190188
- VIN:
- 2T2AZMAA4MC190188

2021 Lexus RX
350 FWD
64,280 mi
$32,991
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 77,452
- Stock #:
- MC190707
- VIN:
- 2T2HZMAA4MC190707

2021 Lexus RX
350 FWD
77,452 mi
$32,676
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 53,020
- Stock #:
- 1411539B
- VIN:
- 2T2HZMAA5LC158783

2020 Lexus RX
350 FWD
53,020 mi
$35,610
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 71,982
- Stock #:
- 36312Q
- VIN:
- 2T2HZMAA6MC211475
2021 Lexus RX
350 FWD
71,982 mi
$28,952
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 67,640
- Stock #:
- 601928A
- VIN:
- 2T2YZMDA8NC356577

2022 Lexus RX
350 F Sport Handling AWD
67,640 mi
$36,520
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 69,887
- Stock #:
- 6447X
- VIN:
- JTJHZKEA6L2016554

2020 Lexus RX
350L FWD
69,887 mi
$33,319
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 64,953
- Stock #:
- NC349209
- VIN:
- 2T2YZMDAXNC349209

2022 Lexus RX
350 F Sport Handling AWD
64,953 mi
$36,944
CarGurus Analysis:
2021 Lexus RX
With 113 currently listed for sale near Naples, FL and an average price of $34,448.00, 62.8% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
100.0% of 2021 RX models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 35,568
- Stock #:
- NC357431
- VIN:
- 2T2AZMDA5NC357431

2022 Lexus RX
350 AWD
35,568 mi
$39,239
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nori Green Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- Automatic
- Mileage:
- 33,813
- Stock #:
- NC232877
- VIN:
- 2T2HZMAA8NC232877

2022 Lexus RX
350 FWD
33,813 mi
$40,460
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 22,671
- Stock #:
- 126220A
- VIN:
- 2T2YZMDA3NC341873

2022 Lexus RX
350 F Sport Handling AWD
22,671 mi
$44,608
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 54,710
- Stock #:
- NC353698
- VIN:
- 2T2YZMDA5NC353698

2022 Lexus RX
350 F Sport Handling AWD
54,710 mi
$37,295
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 61,203
- Stock #:
- 28559945
- VIN:
- 2T2AZMAA9LC181291

2020 Lexus RX
350 FWD
61,203 mi
$33,447
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 58,189
- Stock #:
- LC160849
- VIN:
- 2T2HZMAA8LC160849

2020 Lexus RX
350 FWD
58,189 mi
$31,698
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black/Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 44,790
- Stock #:
- 682623A
- VIN:
- 2T2HZMAA2NC223415

2022 Lexus RX
350 FWD
44,790 mi
$41,968
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Brown (Moonbeam Beige Metallic)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 59,136
- Stock #:
- 161024
- VIN:
- 2T2HZMAA8MC199295

2021 Lexus RX
350 FWD
59,136 mi
$31,499
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Noble Brown
- Transmission:
- Automatic
- Mileage:
- 99,297
- Stock #:
- LC228376
- VIN:
- 2T2JZMDA7LC228376

2020 Lexus RX
350 AWD
99,297 mi
$29,244
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 54,710
- Stock #:
- NC353698
- VIN:
- 2T2YZMDA5NC353698

Sponsored Listing
2022 Lexus RX
350 F Sport Handling AWD
54,710 mi
$37,295
CarGurus Analysis: 2021 Lexus RX
overall

Summary
With 113 currently listed for sale near Naples, FL and an average price of $34,448.00, 62.8% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
100.0% of 2021 RX models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX continues to make a strong case for itself as one of America’s favorite luxury SUVs. For this model year, the body and mechanics are mostly unchanged, but it still stands out for comfortable accommodations, plenty of creature comforts, and Lexus’ long-standing reputation for reliability. It also brings a few tech upgrades for 2021, including new standard safety systems.
What makes the 2021 Lexus RX appealing is the way it balances comfort and value. Its ride quality is a clear strength, and the cabin is designed to be comfortable for everyday use. At the same time, it remains an excellent value for money in the luxury SUV class. The tradeoff is that performance is fairly pedestrian, and the technology can be unintuitive, so buyers who prioritize quick acceleration or a more seamless interface may find it less satisfying.
Other model years to consider
- Average price: $47,535.00
- Good/great deal percentage: 49.2%
- User rating: 5 / 5
- Total listings: 193
- Average price: $33,999.00
- Good/great deal percentage: 55.4%
- User rating: 4.88 / 5
- Total listings: 101
- Average price: $40,257.00
- Good/great deal percentage: 55.3%
- User rating: 4.77 / 5
- Total listings: 161
This analysis is based on CarGurus' proprietary market data from August 25, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 AWD | $46,620 |
| 350 FWD | $45,220 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends2021 Lexus RX Pricing Analysis: Naples, FL Market Report
Pricing by Nearby Locations
Market Area: Naples, FL
Key Insights
- Highest Prices in West Palm Beach: The market in West Palm Beach ($35,621) reflects a premium likely due to higher demand and lower inventory.
- Best Value in Fort Myers: Fort Myers ($34,248) offers the lowest average price, indicating a more competitive market or higher inventory levels.
- Inventory Variation: Cities like North Port (121 listings) and Sarasota (120 listings) show substantial inventory, which may contribute to more stable pricing around the regional average.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| West Palm Beach, FL | 111 | $35,621 |
| North Port, FL | 121 | $34,971 |
| Fort Myers, FL | 115 | $34,248 |
| Sarasota, FL | 120 | $33,398 |
| Sebring, FL | 90 | $33,289 |
| Okeechobee, FL | 101 | $33,289 |
| Homestead, FL | 103 | $33,016 |
| Miami, FL | 115 | $33,062 |
| Fort Lauderdale, FL | 125 | $32,737 |
Pricing by Trim Packages
Key Insights
- FWD vs. AWD Demand: The 350 FWD (198 listings) is the most common trim, indicating a strong preference for front-wheel drive in the region.
- Premium Pricing for F Sport Trims: The 350 F Sport Handling AWD ($52,500 MSRP) is the highest priced trim, reflecting the added features and performance enhancements.
- Limited Inventory for Luxury Trims: The 350L Luxury AWD (1 listing) shows limited availability, suggesting a niche market for high-end features.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 350 FWD | 198 | $45,220 | FWD | 3.5L 295 hp V6 |
| 350 AWD | 92 | $46,620 | AWD | 3.5L 295 hp V6 |
| 350 F Sport AWD | 38 | $50,100 | AWD | 3.5L 295 hp V6 |
| 350 F Sport Handling AWD | 36 | $52,500 | AWD | 3.5L 295 hp V6 |
| 350L AWD | 16 | $49,450 | AWD | 3.5L 290 hp V6 |
| 350L FWD | 23 | $48,050 | FWD | 3.5L 290 hp V6 |
| 350 F Sport FWD | 15 | $48,700 | FWD | 3.5L 295 hp V6 |
| 350L Luxury AWD | 1 | $55,450 | AWD | 3.5L 290 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2026 Lexus RX is priced at $60,497, approximately 17.9% above MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2015 Lexus RX shows the steepest decline, with an average price of $15,395, reflecting a 62.4% drop from MSRP.
- Best Value in Recent Years: The 2022 Lexus RX is priced at $39,801, which is 13.5% below MSRP, making it a compelling option for buyers seeking value.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $51,225 | $60,497 | +17.9% |
| 2025 | $48,975 | $53,328 | +8.8% |
| 2024 | $48,600 | $46,159 | -5.0% |
| 2023 | $47,800 | $49,077 | +2.6% |
| 2022 | $45,920 | $39,801 | -13.5% |
| 2020 | $44,150 | $34,470 | -21.9% |
| 2019 | $43,820 | $29,122 | -33.7% |
| 2018 | $43,470 | $28,813 | -33.7% |
| 2017 | $43,220 | $21,557 | -50.1% |
| 2016 | $41,900 | $23,822 | -43.2% |
| 2015 | $40,970 | $15,395 | -62.4% |
These recommendations are based on CarGurus' proprietary market data from August 27, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus RX cost?
| Metric | Value |
|---|---|
| Current Average Price | $36,191 |
| Year-Round Low | $35,277.46 |
| Year-Round High | $36,803.87 |
| Average Price a Year Ago | $36,638 |
| Change vs. Last Year | −1.22% |
Prices have softened 1.22% compared to this time last year, making it a favorable time to shop this model year.
There are 1,475 listings available, which suggests solid inventory for shoppers comparing trims and conditions.
If you find a listing below $35,277.46, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus RX a good car?
Yes — the 2021 Lexus RX earns a 4.92/5 user rating and a 7.83/10 expert rating. The standout strength is Cost effectiveness at 9/10.
Owners consistently praise its reliability, luxurious features, and smooth driving experience, and they also call out its comfort and handling. The RX is framed as a strong fit if you want a comfortable, everyday luxury SUV with plenty of creature comforts and a reputation for reliability. The main trade-offs are fairly pedestrian performance and technology that can feel unintuitive.
With 36.1% of listings marked as good or great deals, you have some room to shop selectively.
Is the 2021 Lexus RX reliable?
Owners rate it 4.92/5, a strong signal of long-term satisfaction.
Owner feedback repeatedly points to reliability, and the expert evaluation also emphasizes Lexus’ tradition of reliability extending to the RX. That same assessment describes the RX as a comfortable cruiser that remains easy to live with over time. The cost-effectiveness notes also reinforce the idea that this is a model built to deliver value over the long haul.
For used buyers, the main long-term ownership risk is less about durability and more about finding a well-kept example with the right equipment and maintenance history.
What should I look for when buying a used 2021 Lexus RX?
At 74.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a thorough pre-purchase inspection, especially if you are considering a higher-mileage or lower-priced example. Focus on signs of prior bodywork, uneven wear, and any evidence that the vehicle’s comfort and tech features have been neglected. If you want the safest path, compare condition carefully across listings rather than chasing the lowest sticker price.
Key things to evaluate:
- Trim level: The base RX comes with standard 18-inch aluminum wheels, LED lighting, rear privacy glass, and a fairly well-appointed cabin, but the F Sport adds more aggressive styling and performance-oriented touches. The extended-body RXL variants add a third row, while the base models are the simpler two-row choices.
- Powertrain: The standard RX uses a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic. The hybrid versions use a 3.5-liter V6 with three electric motors and an e-CVT, and they are the efficiency play in the lineup.
- Safety package: Lexus Safety System+ 2.0 is standard and includes pre-collision warning with automatic emergency braking, pedestrian and cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. Every RX also gets a rearview camera, 10 airbags, stability control, and blind-spot monitoring with rear cross-traffic alert.
- Infotainment: The standard setup uses an 8-inch touchscreen with Bluetooth, Apple CarPlay, Android Auto, Amazon Alexa, satellite radio, HD Radio, a WiFi hot spot, six USB ports, and a nine-speaker sound system. A 12.3-inch screen, navigation, wireless charging, and upgraded audio are available, but wireless Apple CarPlay and Android Auto are not offered.
- Fuel efficiency: The front-wheel-drive RX 350 returns 20 mpg city, 27 mpg highway, and 23 mpg combined. AWD and RXL versions reduce combined efficiency by 1 mpg, while the RXL with AWD gets 21 mpg combined. The hybrid models return 29 or 31 mpg city and 28 mpg highway, depending on configuration.
Which 2021 Lexus RX trim should I buy?
The 2021 Lexus RX is offered in 5 trim levels: RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid.
Here's the short version:
- Base trim: The RX is the simplest starting point, but it lacks the extended-body third-row layout and the more aggressive F Sport appearance and handling upgrades.
- Sweet-spot trim: The RX F Sport is the best fit if you want the most engaging version of the standard gas model without moving into a different powertrain.
- Premium/top trim: The RXL Hybrid is the most feature-rich choice if you want the added space of the longer body plus hybrid efficiency.
- Off-road trim: None of the trims are aimed at off-road use, so there is no daily-driver caution to flag here.
Lexus Safety System+ 2.0 is standard across the lineup.
Is now a good time to buy a used 2021 Lexus RX?
This is a moderate, selective buyer’s market, so you can shop carefully without expecting every listing to be a bargain.
- Deal availability: 36.1% of listings are priced as good or great deals.
- Inventory: There are 1,475 listings available.
- Price trend: Prices have softened 1.22% compared with last year.
- Clean inventory: 74.8% of listings are accident-free.
If you find a listing below $35,277.46, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus RX's resale value?
The current average of $36,191 sits slightly below last year's $36,638.
That softer pricing suggests the market has eased a bit, which can help you buy more selectively now. For a future seller, it also means the RX is holding value reasonably well rather than showing a sharp drop. Strong demand for comfortable, well-equipped luxury SUVs should continue to support resale interest, especially for clean examples with good history.
Vehicles with strong owner satisfaction ratings, like this model year's 4.92/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus RX safe?
The 2021 Lexus RX earns a Top Safety Pick designation from IIHS and four-star ratings overall from NHTSA, with five-star ratings in side-impact crashworthiness.
It earns a 8/10 safety score from our experts.
Every RX comes standard with Lexus Safety System+ 2.0, which includes pre-collision warning with automatic emergency braking, pedestrian and cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. It also includes a rearview camera, 10 airbags, stability control, and blind-spot monitoring with rear cross-traffic alert.
One caveat is that the longer RXL versions and the hybrid long-wheelbase variant were not tested by IIHS, so you should pay close attention to the exact body style you are considering.
Should I buy a 2021 Lexus RX or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 36.1% of listings are priced as good or great deals.
- At 74.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices have softened 1.22% compared with last year.
- Owners rate it 4.92/5 — a strong satisfaction signal.
- It adds new standard safety systems while keeping the RX’s comfort-focused formula intact.
Consider the 2020 if:
- At $33,645, the 2020 costs less than the current year's $36,191 average.
- It emphasizes comfort, refinement, and everyday usability.
Consider the 2022 if:
- At $39,862, the 2022 costs more than the current year's $36,191 average.
- It adds new colors and a standalone fog lamps option.
The bottom line: If you want the best balance of price, comfort, and updated safety equipment, the 2021 is the smart default. If your budget is tighter, the 2020 can save you money while staying close in character. If you want to spend more for a newer model-year example, the 2022 is a reasonable step up, but the value case is strongest on the 2021.
These recommendations are based on CarGurus' proprietary market data from August 21, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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