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Used 2021 Lexus RX for Sale near Naples, FL

111 results
Naples, FL
2022 Lexus RX 350 F Sport Handling AWD Sawgrass INFINITI

2022 Lexus RX

350 F Sport Handling AWD

61,972 miles

$37,132

Good Deal
Tamarac, FL
93 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
61,972
Stock number:
P18819
VIN:
2T2YZMDA3NC355840

Sponsored

2021 Lexus RX 350L FWD

2021 Lexus RX

350L FWD

78,659 miles

$29,990

Fair Deal
Miami, FL
98 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
78,659
Stock number:
1221499A
VIN:
JTJHZKEA0M2018429

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

33,916 miles

$37,892

Fair Deal
Naples, FL
6 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,916
Stock number:
I224698
VIN:
2T2AZMAAXNC224698

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

37,970 miles

$37,597

Fair Deal
Store transfer to Naples, FL
739 mi away • Price includes $599 shipping Price includes $599 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Green
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
37,970
Stock number:
28144060
VIN:
2T2AZMAA0MC218875

2020 Lexus RX 350 AWD

2020 Lexus RX

350 AWD

70,054 miles

$28,243

Great Deal
Sarasota, FL
88 mi away
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
70,054
Stock number:
9298826A
VIN:
2T2HZMDA4LC241262

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350L FWD

26,798 miles

$39,551

Fair Deal
Naples, FL
10 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
8-Speed Automatic
Mileage:
26,798
Stock number:
SEL21356A
VIN:
JTJHZKEA6M2022503

Preparing for a close up...

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2022 Lexus RX

350 FWD

22,526 miles

$38,787

Good Deal
Miami, FL
92 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
22,526
Stock number:
D5G374940A
VIN:
2T2HZMAA3NC248002

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

34,169 miles

$35,750

Good Deal
Miami, FL
97 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
34,169
Stock number:
9V56451A
VIN:
2T2HZMAA5NC254139

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 FWD

76,848 miles

$30,997

Fair Deal
Store transfer to Naples, FL
2,169 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
76,848
Stock number:
27997692
VIN:
2T2HZMAAXLC173800

Preparing for a close up...

Photos coming soon

2020 Lexus RX

350 AWD

38,289 miles

$35,897

Good Deal
Store transfer to Naples, FL
1,012 mi away • Price includes $899 shipping Price includes $899 shipping
Year:
2020
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
38,289
Stock number:
28041841
VIN:
2T2HZMDA3LC213100

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350L AWD

56,269 miles

$40,597

Fair Deal
Store transfer to Naples, FL
1,203 mi away • Price includes $1,599 shipping Price includes $1,599 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Gray
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
56,269
Stock number:
27993678
VIN:
JTJHZKFA1N2040892

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

33,916 miles

$37,892

Fair Deal
Naples, FL
6 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
33,916
Stock number:
I224698
VIN:
2T2AZMAAXNC224698

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

71,111 miles

$31,988

Great Deal
Fort Myers, FL
28 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nightfall Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
71,111
Stock number:
NC350612
VIN:
2T2HZMDA9NC350612

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport Handling AWD

59,599 miles

$34,997

Good Deal
Cutler Bay, FL
97 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Eminent White Pearl
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
59,599
Stock number:
U295051
VIN:
2T2YZMDA6MC295051

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

42,214 miles

$36,594

Fair Deal
Fort Myers, FL
28 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
42,214
Stock number:
I229578
VIN:
2T2AZMAA3NC229578

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport Handling AWD

50,088 miles

$37,689

Good Deal
Certified Pre-Owned
Sarasota, FL
88 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
50,088
Stock number:
S051694A
VIN:
2T2YZMDA3MC288798

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  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2021
  5. / Florida
  6. / Naples
Overview
Reviews
FAQs

CarGurus Analysis: 2021 Lexus RX

Picture of 2021 Lexus RX

Summary

  • With 1,829 currently listed for sale on CarGurus and an average price of $35,773.40, 32.3% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2021 Lexus RX 4.7 / 5 stars and CarGurus experts gave it an 7.8 / 10.
  • 79% of 2021 RX models on CarGurus are accident free.
  • The 2021 Lexus RX combined luxurious comfort with reliability, featuring upgraded safety technology and a smooth ride, although it had some limitations in performance and technology usability.

Why it stands out

The 2021 Lexus RX distinguished itself as a luxury SUV that emphasized comfort and reliability, making it an appealing choice for buyers seeking both style and practicality. It featured an excellent ride quality and offered great value for money, ensuring a pleasant driving experience. Additionally, the introduction of new standard safety systems enhanced its appeal by prioritizing passenger protection.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.
  • 2022 Lexus RX: This year offers $40,414.56 average price, 36% good/great deals, 4.6/5 user rating, 7.3/10 expert rating, 2,526 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.8 Overall rating

(26 reviews)
Archie C
5.0
Reviewed a 2021 Lexus RX on Oct 13, 2024

Very reliable stylish looking drives well. Good suspension. Fun to drive

Dan F
5.0
Reviewed a 2021 Lexus RX on Mar 26, 2024

Condition of the vehicle was 10/10. Interior was detailed extremely well. Mechanically it all checked out as well. Only issue was since it is a Canadian vehicle the digital climate controls appear to be stuck in Celsius. Could be a troubleshoot to resolve it but other than that perfect vehicle.

Haidar A
5.0
Reviewed a 2021 Lexus 350L AWD on Apr 25, 2024

The car is perfect if only the brakes were as responsive of a German car.

Ann W
5.0
Reviewed a 2021 Lexus RX on Feb 22, 2023

This car is beautiful and drives so smooth.

Anonymous
5.0
Reviewed a 2021 Lexus RX on Nov 04, 2023

Perfect for me and my family (except for the Parchment interior that my kids will probably ruin) but I love it!so I will do everything to keep it clean.. this car is superior family luxury! Have kid? Needs spacious trunk and seating but doesnt want it looking huge and bulky outside? Needs reliability? Need quality? Need LUXURY? look no further the RX 350 IS THE CAR FOR YOU!

2021 Lexus RX FAQs

How much does the 2021 Lexus RX cost in Naples, FL?

The average 2021 Lexus RX costs about $35,564.23. The average price has decreased by -4.1% since last year. The 89 for sale near Naples, FL on CarGurus, range from $21,236 to $47,998 in price.

Is the 2021 Lexus RX a good car?

CarGurus experts gave the 2021 Lexus RX an overall rating of 7.8/10 and 2021 Lexus RX owners have rated the vehicle a 4.7/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2021 Lexus RX vehicles in Naples, FL have no reported accidents or damage?

89 out of 89 for sale near Naples, FL have no reported accidents or damage.

Is the 2021 Lexus RX safe?

CarGurus experts gave the 2021 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2021 Lexus RX?

Depending on the engine and options, the 2021 Lexus RX gets between 21 and 23 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2024 Lexus RX in Naples FL

  • 2023 Lexus RX in Naples FL

  • 2022 Lexus RX in Naples FL

  • 2020 Lexus RX in Naples FL

  • 2019 Lexus RX

  • 2018 Lexus RX

  • Lexus RX 350 FWD

  • Lexus RX 350 AWD

  • Lexus RX 350 F Sport AWD

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L FWD

  • Lexus RX 350L AWD

  • Lexus RX 350 F Sport FWD

  • Lexus RX 350L Luxury AWD

  • Lexus RX 350L Luxury FWD

  • Lexus RX 350 F Sport Handling FWD

  • 2021 Lexus RX in Fort Myers FL

  • 2021 Lexus RX in Sarasota FL

  • 2021 Lexus RX in Miami FL

  • 2021 Lexus RX in Fort Lauderdale FL

  • Lexus RX in Naples FL

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