Used 2021 Lexus IS for Sale near North Carolina
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 50,956
- Stock #:
- M5041271B
- VIN:
- JTHGZ1B23M5041271


Sponsored by Hyundai of Union County
2021 Lexus IS
350 F Sport RWD
50,956 mi
$39,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 48,163
- Stock #:
- XZTB630B
- VIN:
- JTHGZ1B21M5045531

Sponsored Listing
2021 Lexus IS
350 F Sport RWD
48,163 mi
$39,790
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 34,814
- Stock #:
- 1139
- VIN:
- JTHGZ1B25N5049647

Sponsored Listing
2022 Lexus IS
350 F Sport RWD
34,814 mi
$42,777
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 80,681
- Stock #:
- 10393
- VIN:
- JTHGZ1B25M5044009

2021 Lexus IS
350 F Sport RWD
80,681 mi
$34,822
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Black (Caviar)
- Interior color:
- Black W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 25,415
- Stock #:
- N5027259
- VIN:
- JTHGZ1E22N5027259

2022 Lexus IS
350 F SPORT 2 AWD
25,415 mi
$40,998
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 46,000
- Stock #:
- 17976
- VIN:
- JTHGZ1E26L5017976

2020 Lexus IS
350 AWD
46,000 mi
$36,975
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,059
- Stock #:
- 28312840
- VIN:
- JTHGZ1B2XN5053015

2022 Lexus IS
350 F Sport RWD
48,059 mi
$39,697
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,911
- Stock #:
- YN5055906
- VIN:
- JTHGZ1B20N5055906

2022 Lexus IS
350 F Sport RWD
48,911 mi
$37,496
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 48,123
- Stock #:
- PE048604
- VIN:
- JTHD81F24N5048604

2022 Lexus IS
300 AWD
48,123 mi
$33,905
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,695
- Stock #:
- 44431
- VIN:
- JTHGZ1B27N5049374

2022 Lexus IS
350 F Sport RWD
65,695 mi
$38,645
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 56,806
- Stock #:
- 1P053773
- VIN:
- JTHGZ1B28N5053773

2022 Lexus IS
350 F Sport RWD
56,806 mi
$37,844
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Blue Mica
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,855
- Stock #:
- 79017A
- VIN:
- JTHGZ1B22N5049217

2022 Lexus IS
350 F Sport RWD
49,855 mi
$39,898
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 48,163
- Stock #:
- XZTB630B
- VIN:
- JTHGZ1B21M5045531

2021 Lexus IS
350 F Sport RWD
48,163 mi
$39,790
CarGurus Analysis:
2021 Lexus IS
With 520 currently listed for sale and an average price of $35,304.00, 32.5% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
74.0% of 2021 Lexus IS models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 97,974
- Stock #:
- MAS-114114
- VIN:
- JTHAA1D2XM5114114

2021 Lexus IS
300 RWD
97,974 mi
$25,848
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Carmel W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 99,642
- Stock #:
- 3024205
- VIN:
- JTHD81F27N5049066

2022 Lexus IS
300 AWD
99,642 mi
$28,625
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 34,814
- Stock #:
- 1139
- VIN:
- JTHGZ1B25N5049647

2022 Lexus IS
350 F Sport RWD
34,814 mi
$42,777
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- ATOMIC SILVER
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black
- Transmission:
- Automatic
- Mileage:
- 96,003
- Stock #:
- LA042453
- VIN:
- JTHGZ1B23M5042453

2021 Lexus IS
350 F Sport RWD
96,003 mi
$33,326
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- Automatic
- Mileage:
- 40,867
- Stock #:
- MP11468
- VIN:
- JTHCA1D21M5116763

2021 Lexus IS
300 RWD
40,867 mi
$34,796
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red w/Dark Gray Streamline Trim
- Transmission:
- Automatic
- Mileage:
- 68,606
- Stock #:
- 101898
- VIN:
- JTHGA1D24L5101898

2020 Lexus IS
300 RWD
68,606 mi
$26,840
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,569
- Stock #:
- 106750
- VIN:
- JTHGA1D28L5106750

2020 Lexus IS
300 RWD
31,569 mi
$32,028
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 50,956
- Stock #:
- M5041271B
- VIN:
- JTHGZ1B23M5041271

2021 Lexus IS
350 F Sport RWD
50,956 mi
$39,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 40,356
- Stock #:
- M5041065
- VIN:
- JTHGZ1B20M5041065

2021 Lexus IS
350 F Sport RWD
40,356 mi
$39,566
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Black (Caviar)
- Interior color:
- Black W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 25,415
- Stock #:
- N5027259
- VIN:
- JTHGZ1E22N5027259

Sponsored Listing
2022 Lexus IS
350 F SPORT 2 AWD
25,415 mi
$40,998
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 520 currently listed for sale and an average price of $35,304.00, 32.5% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
74.0% of 2021 Lexus IS models on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan that leans hard into style and driving enjoyment. Lexus describes it as entering its fourth generation and drawing lessons from the LC and RC, while also aiming at enthusiast drivers and luxury buyers who might otherwise think German first. That positioning gives the car a clear identity: it is meant to feel more expressive and more driver-focused than a typical small luxury sedan.
Its strongest appeal comes from the combination of stylish design, multiple powertrain options, and great handling. Those traits make it attractive to buyers who want a premium sedan with a sporty edge rather than a purely comfort-oriented commute car. At the same time, the 2021 Lexus IS is not without compromises, and the reported drawbacks include an underwhelming base engine, an irritating transmission, and outdated technology. Owner feedback generally reinforces the car’s style, sporty feel, and luxurious character, while also pointing to missing modern tech features and concerns about fuel efficiency with the smaller engine option.
Other model years to consider
- Average price: $37,941.00
- Good/great deal percentage: 34.8%
- User rating: 5 / 5
- Total listings: 996
- Average price: $41,400.00
- Good/great deal percentage: 34.0%
- User rating: 4.8 / 5
- Total listings: 1,229
- Average price: $42,907.00
- Good/great deal percentage: 34.2%
- Total listings: 1,435
This analysis is based on CarGurus' proprietary market data from August 17, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Dallas: The city of Dallas, TX ($36,138) has the highest average price, indicating strong demand or limited supply in that market.
- Lowest Prices in Miami: Conversely, Miami, FL ($29,366) offers the lowest average price, suggesting a more price-sensitive market or higher inventory levels.
- Inventory Variation: Cities like Los Angeles (97 listings) and Dallas (68 listings) show a healthy inventory, which correlates with their higher average prices compared to cities with fewer listings.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Dallas, TX | 68 | $36,138 |
| Los Angeles, CA | 97 | $36,123 |
| Philadelphia, PA | 65 | $34,132 |
| Houston, TX | 72 | $34,015 |
| Atlanta, GA | 78 | $35,383 |
| New York, NY | 62 | $32,802 |
| Chicago, IL | 55 | $32,550 |
| Washington, DC | 63 | $31,330 |
| Miami, FL | 57 | $29,366 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 300 RWD trim leads in inventory with 556 listings, indicating it is the most popular choice among buyers.
- Price Range Across Trims: The 300 RWD trim has an MSRP of $39,050, while the 350 F Sport AWD trim is priced higher at $44,950, reflecting a premium for sport features.
- AWD vs RWD Demand: The 300 AWD trim, with 263 listings, shows a significant interest in all-wheel-drive options, which may be driven by regional weather conditions.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 556 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 359 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 263 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 94 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2026 Lexus IS is priced at $55,536, which is 22.1% above MSRP, indicating strong demand for the latest model.
- Depreciation Trends: Older models, such as the 2014 Lexus IS, show significant depreciation, with an average price of $16,134, reflecting a -55.3% drop from MSRP.
- Best Value Years: The 2022 Lexus IS is priced at $37,554, which is -4.3% below MSRP, making it a potentially attractive option for buyers looking for value.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Lexus IS | $45,500 | $55,536 | +22.1% |
| 2025 Lexus IS | $40,535 | $46,815 | +15.5% |
| 2024 Lexus IS | $40,085 | $44,475 | +10.9% |
| 2023 Lexus IS | $40,085 | $41,756 | +4.2% |
| 2022 Lexus IS | $39,125 | $37,554 | -4.3% |
| 2020 Lexus IS | $38,560 | $28,012 | -27.4% |
| 2019 Lexus IS | $38,560 | $24,939 | -35.4% |
| 2018 Lexus IS | $38,210 | $23,878 | -37.4% |
| 2017 Lexus IS | $37,825 | $21,066 | -44.6% |
| 2016 Lexus IS | $37,325 | $18,831 | -49.5% |
| 2015 Lexus IS | $36,550 | $17,691 | -51.6% |
| 2014 Lexus IS | $36,100 | $16,134 | -55.3% |
These recommendations are based on CarGurus' proprietary market data from August 20, 2026, CarGurus experts' opinions, and generative AI.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $35,304 |
| Year-Round Low | $33,147.19 |
| Year-Round High | $35,685.81 |
| Average Price a Year Ago | $34,801 |
| Change vs. Last Year | +1.44% |
Prices are up 1.44% year-over-year — a sign of continued demand for this model year.
There are 528 listings available, which gives you a decent amount of inventory to compare before you buy.
If you find a listing below $33,147.19, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus IS a good car?
Yes — the 2021 Lexus IS earns a 4.62/5 user rating, and its expert rating is 7.33/10. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, and luxurious character. They also highlight the handling and value for money, while noting that the car’s safety features are a strong part of its appeal.
The trade-offs are familiar: some owners point to missing modern tech features, and fuel efficiency with the smaller engine option draws criticism. That lines up with the car’s mission as a driver-focused compact luxury sedan rather than a pure comfort-first commuter.
For you, that means the IS makes the most sense if you want a premium small sedan with personality and don’t mind giving up some convenience-tech polish. The market shows 33.1% good or great deals, which suggests there are still worthwhile opportunities if you shop carefully.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
The owner summary points to a car that feels dependable, with buyers repeatedly emphasizing the kind of ownership experience you can count on over time. Lexus also leans on its reputation for quality and reliability in the model’s positioning.
The expert evaluation reinforces that impression by describing the brand’s quality-and-reliability reputation and noting that the IS comes well equipped without pricing getting out of hand. Lexus also includes a 10-year complimentary service-connect subscription, which can help with maintenance awareness.
For used buyers, the main long-term risk is less about outright durability and more about whether the car’s tech and powertrain behavior still suit your expectations after years of use.
What should I look for when buying a used 2021 Lexus IS?
At 74.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if you’re considering a car with a lower price or a sport package. Focus on condition, maintenance records, and whether the car’s technology and drivability still feel current to you.
Key things to evaluate:
- Trim level: The lineup includes the IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, and IS 350 AWD F Sport. The base setup is more restrained, while the F Sport versions add a more aggressive look and sportier positioning.
- Powertrain: The IS 300 RWD uses a 2.0-liter turbocharged four-cylinder with 241 horsepower and 258 pound-feet of torque. The IS 300 AWD uses a 3.5-liter V6 with 260 hp and 236 lb-ft, while IS 350 models use the same V6 tuned to 311 hp and 280 lb-ft. RWD models use an eight-speed automatic, and AWD models use a six-speed automatic.
- Safety package: Lexus Safety System+ 2.5 is standard and includes pre-collision with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also adds blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
- Infotainment: The IS finally gets a touchscreen infotainment system with Android Auto and Apple CarPlay. Lexus Enform Remote, Service Connect, and WiFi are part of the connected-services mix, and the Navigation Package adds Dynamic Navigation and Destination Assist for the first three years.
- Fuel efficiency: The EPA estimates 21 mpg city, 31 mpg highway, and 25 mpg combined for the IS 300 RWD; 19/26/22 for the IS 300 AWD; 20/28/23 for the IS 350 RWD; and 19/26/22 for the IS 350 AWD.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- Base trim: The IS 300 RWD gives you the lowest entry price, but it also comes with the underwhelming base engine trade-off noted in the model’s broader evaluation.
- Sweet-spot trim: The IS 300 AWD is the better all-weather choice if you want the V6 without stepping all the way up to the sportier F Sport pricing.
- Premium/top trim: The IS 350 AWD F Sport is the strongest pick if you want the most power and the most upscale sport-sedan feel from this lineup.
Lexus Safety System+ 2.5 is standard across the lineup, so you’re not giving up the core driver-assistance suite by staying with a lower trim.
Is now a good time to buy a used 2021 Lexus IS?
This looks like a moderate, selective buyer’s market, so you can shop patiently but still move quickly on the right car.
- Deal availability: 33.1% of listings are priced as good or great deals.
- Inventory: There are 528 listings available.
- Price trend: Prices are up 1.44% year-over-year.
- Clean inventory: 74.6% of listings are accident-free.
If you find a listing below $33,147.19, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $35,304 sits slightly above last year's $34,801.
That kind of upward movement suggests the market still sees value in this model year, which can help support resale strength if you buy well and keep the car in good condition. A stable-to-rising price trend also gives you a better chance of limiting depreciation compared with a model that’s sliding quickly.
Because demand appears steady and the car has a clear enthusiast appeal, a clean example with strong equipment and good records should remain easier to sell later. Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
It hasn’t yet been rated for crashworthiness by IIHS, and it has not received an overall rating from NHTSA.
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes pre-collision with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. You also get blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect with SOS emergency assistance, roadside assistance, automatic collision notification, and stolen vehicle notification.
The main caveat is that the model’s crash-test results were not yet published at the time of evaluation, so you should lean heavily on the standard safety suite and the car’s condition when shopping used.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 33.1% of listings are priced as good or great deals.
- At 74.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 1.44% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 brings a fourth-generation redesign with a sharper focus on sporty handling and updated tech.
Consider the 2022 if:
- At $37,839, the 2022 costs more than the current year's $35,304 average.
- It adds the IS 500 F Sport Performance with a V8 and much stronger performance.
The bottom line: If you want the better value, the 2021 is the smarter starting point because it delivers the redesign, strong owner satisfaction, and a lower average price. If you’re a performance-first buyer and can stretch your budget, the 2022 is worth a look for its added power and enthusiast appeal.
These recommendations are based on CarGurus' proprietary market data from August 21, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.

Best Lexus Deals in August 2026
Leasing a Lexus can be a great way to get into a new car from one of the most popular luxury brands at a more affordable monthly rate. Here are the best deals we've found this month on Lexus vehicles.

2026 Lexus IS Pricing, Specs, and Release Date
The Lexus IS gets a refresh for 2026 with new styling touches, a bigger infotainment display and instrument cluster, and retuned driving dynamics.