Used 2021 Lexus IS for Sale near New Hampshire
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Mileage:
- 52,749
- Stock #:
- N6100460C
- VIN:
- JTHA81F22L5041389


Sponsored by Nucar Honda of Westford
2020 Lexus IS
300 AWD
52,749 mi
$28,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 80,338
- Stock #:
- 28892318
- VIN:
- JTHAA1D28M5111146

2021 Lexus IS
300 RWD
80,338 mi
$26,397
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 22,747
- Stock #:
- 28575178
- VIN:
- JTHAA1D26N5122650

2022 Lexus IS
300 RWD
22,747 mi
$35,597
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red (BURGUNDY)
- Transmission:
- Automatic
- Mileage:
- 29,923
- Stock #:
- 70215663
- VIN:
- JTHD81F29N5049781

2022 Lexus IS
300 AWD
29,923 mi
$38,997
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,699
- Stock #:
- 44431
- VIN:
- JTHGZ1B27N5049374

2022 Lexus IS
350 F Sport RWD
65,699 mi
$39,355
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 47,000
- Stock #:
- WEB547841
- VIN:
- JTHGZ1E26L5017976

2020 Lexus IS
350 AWD
47,000 mi
$36,975
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red (BURGUNDY)
- Transmission:
- Automatic
- Mileage:
- 43,493
- Stock #:
- 28822005
- VIN:
- JTHAA1D2XN5119394

2022 Lexus IS
300 RWD
43,493 mi
$34,097
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Blue
- Transmission:
- Automatic
- Mileage:
- 66,064
- Stock #:
- 28207434
- VIN:
- JTHDA1D28L5108162

2020 Lexus IS
300 RWD
66,064 mi
$29,597
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,569
- Stock #:
- 106750
- VIN:
- JTHGA1D28L5106750

2020 Lexus IS
300 RWD
31,569 mi
$33,112
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red w/Dark Gray Streamline Trim
- Transmission:
- Automatic
- Mileage:
- 68,606
- Stock #:
- 101898
- VIN:
- JTHGA1D24L5101898

2020 Lexus IS
300 RWD
68,606 mi
$26,894
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gold
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 122,272
- Stock #:
- 040470
- VIN:
- JTHGZ1B24M5040470

2021 Lexus IS
350 F Sport RWD
122,272 mi
$29,110
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red (BURGUNDY)
- Transmission:
- Automatic
- Mileage:
- 65,279
- Stock #:
- 70165915
- VIN:
- JTHGA1D23L5101150

2020 Lexus IS
300 RWD
65,279 mi
$30,997
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Mileage:
- 52,749
- Stock #:
- N6100460C
- VIN:
- JTHA81F22L5041389

2020 Lexus IS
300 AWD
52,749 mi
$28,998
CarGurus Analysis:
2021 Lexus IS
With 522 currently listed for sale and an average price of $34,946.00, 30.8% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
72.8% of 2021 Lexus IS models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 46,334
- Stock #:
- 025834
- VIN:
- JTHGZ1E20N5025834

2022 Lexus IS
350 F SPORT AWD
46,334 mi
$41,066
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Other
- Transmission:
- 8-Speed Automatic
- Mileage:
- 79,867
- Stock #:
- 037718
- VIN:
- JTHGZ1B2XM5037718

2021 Lexus IS
350 F Sport RWD
79,867 mi
$36,512
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 105,850
- Stock #:
- 046102
- VIN:
- JTHC81F20M5046102

2021 Lexus IS
300 AWD
105,850 mi
$27,469
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,056
- Stock #:
- N5054202
- VIN:
- JTHGZ1B23N5054202

2022 Lexus IS
350 F Sport RWD
59,056 mi
$39,640
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red 31
- Transmission:
- Automatic
- Mileage:
- 55,587
- Stock #:
- P3013
- VIN:
- JTHCA1D2XM5109455

2021 Lexus IS
300 RWD
55,587 mi
$31,889
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 82,035
- Stock #:
- M5043765
- VIN:
- JTHC81F20M5043765

2021 Lexus IS
300 AWD
82,035 mi
$32,176
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Blue Mica
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 32,343
- Stock #:
- N5026483P
- VIN:
- JTHGZ1E22N5026483

2022 Lexus IS
350 F SPORT 2 AWD
32,343 mi
$44,971
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Carmel W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 26,253
- Stock #:
- P26790
- VIN:
- JTHDA1D29N5119903

2022 Lexus IS
300 RWD
26,253 mi
$35,872
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 77,701
- Stock #:
- 040164
- VIN:
- JTHGZ1B28M5040164

2021 Lexus IS
350 F Sport RWD
77,701 mi
$32,476
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Blue Mica
- Interior color:
- Black W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 46,937
- Stock #:
- N5026307
- VIN:
- JTHGZ1E24N5026307

2022 Lexus IS
350 F SPORT 2 AWD
46,937 mi
$41,738
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 522 currently listed for sale and an average price of $34,946.00, 30.8% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
72.8% of 2021 Lexus IS models on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan that leans hard into style and driving enjoyment. Lexus describes it as entering its fourth generation and drawing lessons from the LC and RC, while also aiming at enthusiast drivers and luxury buyers who might otherwise think German first. That positioning gives the car a clear identity: it is meant to feel more expressive and more driver-focused than a typical small luxury sedan.
Its strongest appeal comes from the combination of stylish design, multiple powertrain options, and great handling. Those traits make it attractive to buyers who want a premium sedan with a sporty edge rather than a purely comfort-oriented commute car. At the same time, the 2021 Lexus IS is not without compromises, and the reported drawbacks include an underwhelming base engine, an irritating transmission, and outdated technology. Owner feedback generally reinforces the car’s style, sporty feel, and luxurious character, while also pointing to missing modern tech features and concerns about fuel efficiency with the smaller engine option.
Other model years to consider
- Average price: $37,881.00
- Good/great deal percentage: 34.0%
- User rating: 5 / 5
- Total listings: 937
- Average price: $42,691.00
- Good/great deal percentage: 35.8%
- Total listings: 1,392
- Average price: $40,898.00
- Good/great deal percentage: 34.9%
- User rating: 4.8 / 5
- Total listings: 1,196
This analysis is based on CarGurus' proprietary market data from August 31, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Dallas: The city of Dallas, TX ($36,850) has the highest average price, likely reflecting a strong demand for luxury vehicles in the area.
- Lowest Prices in Miami: Miami, FL ($29,137) offers the lowest average price, suggesting a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like Los Angeles (92 listings) and Dallas (70 listings) have a significant number of listings, indicating a healthy supply that may stabilize prices compared to lower inventory markets.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Dallas, TX | 70 | $36,850 |
| Philadelphia, PA | 61 | $36,964 |
| Los Angeles, CA | 92 | $35,301 |
| New York, NY | 61 | $34,853 |
| Washington, DC | 61 | $29,976 |
| Atlanta, GA | 79 | $32,260 |
| Houston, TX | 65 | $30,789 |
| Miami, FL | 54 | $29,137 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 300 RWD trim leads in inventory with 574 listings, indicating strong demand for this base model.
- Price Range Across Trims: The 350 F Sport RWD trim, priced at $42,950 MSRP, reflects a premium for sport features, while the 300 AWD trim is positioned at $41,050 MSRP, appealing to those seeking all-weather capability.
- Feature-Rich Offerings: All trims include popular features such as Backup Camera, Bluetooth, and Adaptive Cruise Control, enhancing their market appeal.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 574 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 382 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 269 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 97 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models Command Premium: The 2026 Lexus IS is priced at $55,376, reflecting a 21.6% increase over its original MSRP, indicating strong demand for the latest model.
- Depreciation Trends: Older models, such as the 2014 Lexus IS, show significant depreciation, with an average price of $16,530, down 54.2% from MSRP.
- Best Value Years: The 2022 Lexus IS is priced at $37,902, which is only -3.1% below its MSRP, making it a compelling option for buyers looking for recent models with minimal depreciation.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Lexus IS | $45,500 | $55,376 | +21.6% |
| 2025 Lexus IS | $40,535 | $47,614 | +17.4% |
| 2024 Lexus IS | $40,085 | $43,963 | +9.0% |
| 2023 Lexus IS | $40,085 | $41,786 | +4.2% |
| 2022 Lexus IS | $39,125 | $37,902 | -3.1% |
| 2020 Lexus IS | $38,560 | $28,031 | -27.3% |
| 2019 Lexus IS | $38,560 | $25,383 | -34.1% |
| 2018 Lexus IS | $38,210 | $24,191 | -36.7% |
| 2017 Lexus IS | $37,825 | $21,010 | -44.8% |
| 2016 Lexus IS | $37,325 | $18,945 | -49.3% |
| 2015 Lexus IS | $36,550 | $17,835 | -51.2% |
| 2014 Lexus IS | $36,100 | $16,530 | -54.2% |
These recommendations are based on CarGurus' proprietary market data from September 3, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $34,916 |
| Year-Round Low | $33,095.87 |
| Year-Round High | $35,639.81 |
| Average Price a Year Ago | $34,035 |
| Change vs. Last Year | +2.59% |
Prices are up 2.59% year-over-year — a sign of continued demand for this model year.
There are 537 listings available, which gives you a modest amount of inventory to compare before you buy.
If you find a listing below $33,095.87, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus IS a good car?
Yes — the 2021 Lexus IS earns a 4.62/5 user rating, and its expert rating is 7.33/10. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, and luxurious character. They also call out the handling and value for money, which fits a car that aims to feel more expressive than a typical compact luxury sedan.
The trade-offs are familiar: the base engine is underwhelming, the transmission can be irritating, and the tech can feel outdated. That matters most if you want a daily driver that prioritizes easy comfort and the latest features over personality.
For you, the appeal is strongest if you want a premium sedan with a sporty edge rather than a purely comfort-first commuter. The market still shows 33.5% good or great deals, so there are still some attractive opportunities if you shop carefully.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
The owner feedback points to a car that feels dependable, with many drivers emphasizing the car’s long-term appeal, luxurious character, and overall confidence in ownership. Lexus also leans on its reputation for quality and reliability, which reinforces that message.
On the expert side, the car’s engineering focus on linear, faithful response and its crisp, balanced chassis tuning support the sense that it should be easy to live with over time. Lexus also includes a 10-year complimentary service-connect subscription, which can help you stay on top of maintenance reminders.
For used buyers, the main long-term risk is less about outright durability and more about whether the specific car has been maintained well and whether you can live with its older-feeling tech.
What should I look for when buying a used 2021 Lexus IS?
At 72.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if the car has had bodywork or multiple owners. Focus on condition, maintenance records, and whether the car’s electronics and driver-assistance features work as intended.
Key things to evaluate:
- Trim level: The lineup includes rear-wheel-drive and all-wheel-drive versions, and the F Sport models add a more aggressive setup and sportier character. The base versions are the ones most likely to leave you wanting more if you care about the full luxury-sport experience.
- Powertrain: You can choose between a 2.0-liter turbo four-cylinder in the rear-wheel-drive IS 300, a naturally aspirated 3.5-liter V6 in the all-wheel-drive IS 300, and a higher-output 3.5-liter V6 in the IS 350. Fuel economy ranges from 21 mpg city, 31 mpg highway, 25 mpg combined in the IS 300 RWD to 19/26/22 in the IS 300 AWD and IS 350 AWD.
- Safety package: Lexus Safety System+ 2.5 is standard, with pre-collision braking and pedestrian detection, lane-departure warning with steering assist, road-sign recognition, lane-tracing assist, full-speed adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring, rear cross-traffic alert, and a backup camera with dynamic gridlines.
- Infotainment: The touchscreen infotainment system supports both Android Auto and Apple CarPlay. Lexus also includes connected services, with wireless app integration and trial subscriptions for several features.
- Fuel efficiency: The EPA estimates 21 mpg city, 31 mpg highway, 25 mpg combined for the IS 300 RWD, 19/26/22 for the IS 300 AWD, 20/28/23 for the IS 350 RWD, and 19/26/22 for the IS 350 AWD.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- IS 300 RWD: This is the least expensive way into the lineup, and it gives you the rear-wheel-drive setup with the turbocharged four-cylinder. It makes the most sense if you want the lowest entry price and still care about the car’s sporty personality.
- IS 300 AWD: Choose this if you want the V6 and all-weather traction without stepping up to the F Sport models. It adds power over the RWD base trim, but it is also pricier and less efficient.
- IS 350 RWD F Sport: This is the best-value choice if you want the strongest blend of performance and equipment. It brings the higher-output V6 and the F Sport treatment, which better matches the car’s enthusiast mission.
- IS 350 AWD F Sport: Pick this if you want the top non-hybrid gas model with all-wheel drive and the most performance-oriented setup in the lineup. It is the most expensive trim, so it suits you best if you want the fullest expression of the IS without compromise.
Lexus Safety System+ 2.5 is standard across the lineup, so you do not need to move up trims to get the core driver-assistance suite.
Is now a good time to buy a used 2021 Lexus IS?
This looks like a moderate, selective buyer’s market, so you should shop with patience and compare listings carefully.
- Deal availability: 33.5% of listings are priced as good or great deals.
- Inventory: There are 537 listings available.
- Price trend: Prices are up 2.59% year-over-year.
- Clean inventory: 72.6% of listings are accident-free.
If you find a listing below $33,095.87, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $34,916 sits slightly above last year's $34,035.
That upward move suggests the market has been willing to pay a bit more for this model year, which is a positive sign if you plan to sell later. It also tells you that well-kept examples may hold their appeal better than you might expect in a competitive luxury-sedan segment.
For you, the key resale takeaway is that condition and history will matter a lot. A clean, well-maintained car should be easier to move than one with accident history or neglected maintenance.
Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes a pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, and left-turn intersection support. It also brings lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, intelligent high beams, blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
The main caveat is that this model year had not yet been rated for crashworthiness by IIHS or NHTSA at the time of the data. That means you should lean more heavily on the standard safety equipment and the condition of the specific car you’re considering.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 33.5% of listings are priced as good or great deals.
- At 72.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 2.59% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 model year brings a major redesign with sharper handling, updated tech, and standard advanced safety features.
Consider the 2022 if:
- At $37,988, the 2022 costs more than the current year's $34,916 average.
- It adds the IS 500 F Sport Performance with a 5.0-liter V8.
The bottom line: If you want the best balance of price, style, and updated features, the 2021 is the smarter buy. If you are willing to spend more for a bigger performance leap, the 2022 is the better path for enthusiast buyers.
These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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