Used 2021 Lexus IS for Sale near New Hampshire
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 48,244
- Stock #:
- AB7962
- VIN:
- JTHGZ1E26M5021754


Sponsored by Autobahn USA
2021 Lexus IS
350 F Sport AWD
48,244 mi
$39,495
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Ultra White
- Interior color:
- Circuit Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 64,641
- Stock #:
- 1701561A
- VIN:
- JTHGZ1E24N5024041

Sponsored Listing
2022 Lexus IS
350 F SPORT 2 AWD
64,641 mi
$39,989
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,375
- Stock #:
- 29074515
- VIN:
- JTHGZ1B28M5038396

2021 Lexus IS
350 F Sport RWD
25,375 mi
$40,697
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Blue
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 70,831
- Stock #:
- 025477
- VIN:
- JTHGZ1E22N5025477

-$2,000
2022 Lexus IS
350 F SPORT 2 AWD
70,831 mi
$37,102
$35,102
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 68,273
- Stock #:
- 70174491
- VIN:
- JTHAA1D28L5106866

2020 Lexus IS
300 RWD
68,273 mi
$28,097
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Mileage:
- 47,993
- Stock #:
- 024754
- VIN:
- JTHGZ1E28N5024754

2022 Lexus IS
350 F SPORT AWD
47,993 mi
$37,107
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 42,814
- Stock #:
- 122349
- VIN:
- JTHAA1D29N5122349

2022 Lexus IS
300 RWD
42,814 mi
$32,711
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Blue Mica
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 32,343
- Stock #:
- N5026483P
- VIN:
- JTHGZ1E22N5026483

-$2,948
2022 Lexus IS
350 F SPORT 2 AWD
32,343 mi
$44,971
$42,023
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 53,216
- Stock #:
- 1701026A
- VIN:
- JTHD81F24N5047677
Photos coming soon
2022 Lexus IS
300 AWD
53,216 mi
$36,459
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red w/Dark Gray Streamline Trim
- Transmission:
- Automatic
- Mileage:
- 68,606
- Stock #:
- 101898
- VIN:
- JTHGA1D24L5101898

2020 Lexus IS
300 RWD
68,606 mi
$26,894
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 47,000
- Stock #:
- WEB547841
- VIN:
- JTHGZ1E26L5017976

2020 Lexus IS
350 AWD
47,000 mi
$36,975
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,569
- Stock #:
- 106750
- VIN:
- JTHGA1D28L5106750

2020 Lexus IS
300 RWD
31,569 mi
$33,112
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 105,850
- Stock #:
- 046102
- VIN:
- JTHC81F20M5046102

2021 Lexus IS
300 AWD
105,850 mi
$27,469
CarGurus Analysis:
2021 Lexus IS
With 532 currently listed for sale and an average price of $34,819, 34.6% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
73.7% of 2021 Lexus IS models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red 31
- Transmission:
- Automatic
- Mileage:
- 55,587
- Stock #:
- P3013
- VIN:
- JTHCA1D2XM5109455

2021 Lexus IS
300 RWD
55,587 mi
$31,889
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gold
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 122,272
- Stock #:
- 040470
- VIN:
- JTHGZ1B24M5040470

2021 Lexus IS
350 F Sport RWD
122,272 mi
$29,110
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Ultra White
- Interior color:
- Circuit Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 64,641
- Stock #:
- 1701561A
- VIN:
- JTHGZ1E24N5024041

2022 Lexus IS
350 F SPORT 2 AWD
64,641 mi
$39,989
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 47,141
- Stock #:
- M5021286
- VIN:
- JTHGZ1E2XM5021286

2021 Lexus IS
350 F Sport AWD
47,141 mi
$41,643
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 68,379
- Stock #:
- M5018473
- VIN:
- JTHGZ1E25M5018473

2021 Lexus IS
350 F Sport AWD
68,379 mi
$39,176
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 82,035
- Stock #:
- M5043765
- VIN:
- JTHC81F20M5043765

-$770
2021 Lexus IS
300 AWD
82,035 mi
$32,176
$31,406
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 158,694
- Stock #:
- O3411311
- VIN:
- JTHD81F21N5049032

2022 Lexus IS
300 AWD
158,694 mi
$22,805
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 44,927
- Stock #:
- MH3467
- VIN:
- JTHG81F2XL5042736

2020 Lexus IS
300 AWD
44,927 mi
$34,372
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Other
- Transmission:
- 8-Speed Automatic
- Mileage:
- 79,867
- Stock #:
- 037718
- VIN:
- JTHGZ1B2XM5037718

2021 Lexus IS
350 F Sport RWD
79,867 mi
$36,512
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,435
- Stock #:
- 057549
- VIN:
- JTHGZ1B21N5057549

2022 Lexus IS
350 F Sport RWD
45,435 mi
$41,625
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 532 currently listed for sale and an average price of $34,819, 34.6% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
73.7% of 2021 Lexus IS models on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan with a sharper sense of purpose than many buyers might expect. Lexus says it amps up the model for a new generation, and the car is described as entering its fourth generation of production while drawing lessons from the LC and RC. It is aimed at enthusiast drivers and luxury shoppers who might otherwise think German first, which helps define the IS as a car built to change expectations rather than simply follow them.
Its strongest appeal comes from the combination of stylish design, multiple powertrain options, and great handling. Those traits make it attractive to buyers who want a sedan that feels more engaging than purely comfort-focused alternatives. At the same time, the 2021 Lexus IS is not without drawbacks: the base engine is described as underwhelming, the transmission as irritating, and the technology as outdated. That mix gives the car a clear personality — appealing for its looks and driving character, but less convincing if a buyer prioritizes the latest tech or a more polished powertrain experience.
Owners’ impressions generally reinforce that balance. Reviewers praise the stylish design, sporty feel, luxurious feel, handling, safety features, and value for money, while some are disappointed by the lack of certain modern tech features such as real-time GPS tracking and wireless Apple CarPlay.
Other model years to consider
- Average price: $37,995
- Good/great deal percentage: 35.4%
- User rating: 5 / 5
- Total listings: 957
- Average price: $40,793
- Good/great deal percentage: 36.1%
- User rating: 4.8 / 5
- Total listings: 1,226
- Average price: $42,661
- Good/great deal percentage: 35.6%
- Total listings: 1,415
This analysis is based on CarGurus' proprietary market data from September 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Boston: The market in Boston, MA ($41,998) reflects a premium likely due to higher demand and limited inventory.
- Lowest Prices in Miami: Miami, FL ($28,769) offers the most competitive pricing, indicating a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like New York (70 listings) and Los Angeles (95 listings) show stable pricing around $34K–$36K, suggesting a balanced supply-demand dynamic.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Boston, MA | 60 | $41,998 |
| Chicago, IL | 54 | $36,426 |
| Philadelphia, PA | 69 | $37,316 |
| Dallas, TX | 76 | $35,819 |
| New York, NY | 70 | $35,357 |
| Los Angeles, CA | 95 | $34,722 |
| Atlanta, GA | 81 | $33,293 |
| Houston, TX | 72 | $31,754 |
| Washington, DC | 68 | $28,780 |
| Miami, FL | 56 | $28,769 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 300 RWD (570 listings) is the most prevalent trim, indicating strong demand for this configuration.
- Price Range Across Trims: The 350 F Sport AWD ($44,950 MSRP) is the highest priced trim, reflecting a premium for performance features.
- AWD vs RWD Demand: The 300 AWD (264 listings) shows a solid inventory, suggesting a balanced interest in all-wheel-drive options.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 570 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 403 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 264 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 108 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models Command Premium: The 2026 Lexus IS is priced at $55,348, approximately 21.6% above MSRP, indicating strong demand for the latest model.
- Depreciation Trends: Older models, particularly the 2014 Lexus IS, show significant depreciation, with prices dropping to $16,342, reflecting a ~54.8% decline from MSRP.
- Best Value Years: The 2022 Lexus IS is priced at $37,873, only 3.2% below MSRP, making it a compelling option for buyers seeking recent models with minimal depreciation.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Lexus IS | $45,500 | $55,348 | +21.6% |
| 2025 Lexus IS | $40,535 | $47,806 | +17.9% |
| 2024 Lexus IS | $40,085 | $44,081 | +9.9% |
| 2023 Lexus IS | $40,085 | $41,587 | +3.7% |
| 2022 Lexus IS | $39,125 | $37,873 | -3.2% |
| 2020 Lexus IS | $38,560 | $28,046 | -27.3% |
| 2019 Lexus IS | $38,560 | $25,049 | -35.2% |
| 2018 Lexus IS | $38,210 | $23,829 | -37.5% |
| 2017 Lexus IS | $37,825 | $21,003 | -44.5% |
| 2016 Lexus IS | $37,325 | $19,017 | -49.1% |
| 2015 Lexus IS | $36,550 | $17,901 | -51.0% |
| 2014 Lexus IS | $36,100 | $16,342 | -54.8% |
These recommendations are based on CarGurus' proprietary market data from September 10, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $34,700 |
| Year-Round Low | $33,092 |
| Year-Round High | $35,568 |
| Average Price a Year Ago | $34,122 |
| Change vs. Last Year | +1.69% |
Prices are up 1.69% year-over-year — a sign of continued demand for this model year.
There are 540 listings available, which gives you a modest amount of inventory to compare before you buy.
Is the 2021 Lexus IS a good car?
Yes — the 2021 Lexus IS earns a 4.62/5 user rating and a 7.33/10 expert rating. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, luxurious feel, handling, and value for money. The overview also points to a car aimed at enthusiast drivers and luxury shoppers who want something more engaging than a typical comfort-first sedan.
The main trade-offs are the underwhelming base engine, the irritating transmission, and outdated technology. That means you should like the IS most if you care more about character, design, and driving feel than the latest cabin tech.
With 31.5% of listings marked as good or great deals, you still have room to shop selectively.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
The owner summary also points to a car that feels dependable, with praise for its luxurious feel, handling, and value for money. Lexus’s reputation for quality and reliability is reinforced in the cost-effectiveness notes, which describe the brand’s quality and reliability as a major advantage.
The expert notes also support that impression by emphasizing the brand’s quality focus and the car’s well-rounded execution. For used buyers, the main long-term ownership risk is less about basic durability and more about living with the car’s dated tech and less polished powertrain behavior.
What should I look for when buying a used 2021 Lexus IS?
At 72.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if you’re comparing cars with similar prices. Focus on overall condition, signs of prior repair, and whether the car’s equipment and features still work as expected.
Key things to evaluate:
- Trim level: The IS 300 RWD starts at $39,000, the IS 300 AWD starts at $41,000, the IS 350 RWD F Sport starts at $42,900, and the IS 350 AWD F Sport starts at $44,900. The base setup gives you the core luxury-sedan experience, while the F Sport versions add the more aggressive performance-oriented presentation and are the better fit if you want the sportiest look and feel.
- Powertrain: The IS 300 RWD uses a 2.0-liter turbocharged inline-four with 241 horsepower and 258 pound-feet of torque. The IS 300 AWD uses a naturally aspirated 3.5-liter V6 with 260 horsepower and 236 pound-feet of torque, while the IS 350 models use the same V6 tuned to 311 horsepower and 280 pound-feet of torque. RWD models use an eight-speed automatic, and AWD models use a six-speed automatic.
- Safety package: Lexus Safety System+ 2.5 is standard and includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. It also includes blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect.
- Infotainment: The IS uses a touchscreen infotainment system with Android Auto and Apple CarPlay. Lexus Enform Safety Connect comes with a three-year trial, Lexus Enform Service Connect comes with a 10-year complimentary subscription, Lexus Enform WiFi includes a 4GB/three-month trial, and Lexus Enform Remote is free for three years.
- Fuel efficiency: The IS 300 RWD is rated at 21 mpg city, 31 mpg highway, and 25 mpg combined. The IS 300 AWD is rated at 19/26/22, the IS 350 RWD at 20/28/23, and the IS 350 AWD at 19/26/22.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- IS 300 RWD: This is the least expensive way into the lineup and the best-value choice if you want the IS’s style, handling, and core luxury feel without paying for extra power or AWD.
- IS 300 AWD: Choose this if you want the V6 powertrain and all-weather traction, and you’re willing to pay more for the added hardware.
- IS 350 RWD F Sport: This is the strongest pick for shoppers who want the most engaging rear-drive setup and the sportiest character in the lineup.
- IS 350 AWD F Sport: Pick this if you want the top-end powertrain with AWD and the full F Sport treatment.
Lexus Safety System+ 2.5 is standard across the lineup.
Is now a good time to buy a used 2021 Lexus IS?
This looks like a moderate, selective buyer’s market, so you can shop patiently but still move quickly on the right car.
- Deal availability: 31.5% of listings are priced as good or great deals.
- Inventory: There are 540 listings available.
- Price trend: Prices are up 1.69% year-over-year.
- Clean inventory: 72.6% of listings are accident-free.
If you find a listing below $33,092, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $34,700 sits slightly above last year's $34,122.
That kind of price movement suggests the market has held up reasonably well for this model year. If you buy now and keep the car in good condition, you’re starting from a price point that still reflects steady demand rather than a sharp drop.
For a future seller, that matters because a stable market can help soften depreciation. The IS’s strong owner satisfaction also supports buyer interest when it’s time to resell.
Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
The 2021 Lexus IS hasn’t yet been rated for crashworthiness by the Insurance Institute for Highway Safety or received an overall rating from the National Highway Traffic Safety Administration.
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. You also get blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect with SOS emergency assistance, roadside assistance, automatic collision notification, and stolen vehicle notification.
The main caveat is that the model lacks formal crash-test results in the provided data, so you’re relying on the standard safety equipment rather than published ratings.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 31.5% of listings are priced as good or great deals.
- At 72.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 1.69% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 model launches the fourth generation with sharper styling, improved driving character, and a touchscreen infotainment system.
Consider the 2022 if:
- At $37,891, the 2022 costs more than the current year's $34,700 average.
- It adds a new IS 500 F Sport Performance with a V8 and much stronger performance.
The bottom line: If you want the better value, the 2021 is the smarter buy because it delivers the redesigned fourth-generation IS experience at a lower average price. If you’re willing to spend more for a bigger performance jump, the 2022 is the better path.
These recommendations are based on CarGurus' proprietary market data from September 11, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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