Used 2021 Lexus IS for Sale nearDes Moines, IA
53 vehicles found
See the total price upfront.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,527
- Stock #:
- 28643418
- VIN:
- JTHGZ1E24N5025433
2022 Lexus IS
350 F SPORT AWD
41,527 mi
$39,497
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 63,341
- Stock #:
- 27983448
- VIN:
- JTHDA1D24N5120666
2022 Lexus IS
300 RWD
63,341 mi
$32,797
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 29,740
- Stock #:
- 70098898
- VIN:
- JTHAA1D27M5112322
2021 Lexus IS
300 RWD
29,740 mi
$33,597
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 69,840
- Stock #:
- 28884302
- VIN:
- JTHCA1D24M5116160
2021 Lexus IS
300 RWD
69,840 mi
$30,797
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 62,990
- Stock #:
- 27906955
- VIN:
- JTHGA1D28L5106358
2020 Lexus IS
300 RWD
62,990 mi
$28,747
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- TAUPE
- Transmission:
- Automatic
- Mileage:
- 107,519
- Stock #:
- 27889629
- VIN:
- JTHDA1D27L5102045
2020 Lexus IS
300 RWD
107,519 mi
$23,397
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 50,492
- Stock #:
- 70036354
- VIN:
- JTHAA1D20L5102584
2020 Lexus IS
300 RWD
50,492 mi
$29,397
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 48,123
- Stock #:
- PE048604
- VIN:
- JTHD81F24N5048604
2022 Lexus IS
300 AWD
48,123 mi
$35,008
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,083
- Stock #:
- 28517958
- VIN:
- JTHGZ1B29N5053197
2022 Lexus IS
350 F Sport RWD
30,083 mi
$37,597
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 68,817
- Stock #:
- 043333
- VIN:
- JTHGZ1B29M5043333
2021 Lexus IS
350 F Sport RWD
68,817 mi
$37,258
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 26,865
- Stock #:
- 102114
- VIN:
- JTHAA1D25L5102113
2020 Lexus IS
300 RWD
26,865 mi
$31,189
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 32,360
- Stock #:
- 049952
- VIN:
- JTHD81F2XN5049952
2022 Lexus IS
300 AWD
32,360 mi
$38,959
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 36,808
- Stock #:
- 28513711
- VIN:
- JTHC81F27M5044282
2021 Lexus IS
300 AWD
36,808 mi
$36,097
CarGurus Analysis:
2021 Lexus IS
With 480 currently listed for sale and an average price of $35,631.00, 29.0% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
73.8% of 2021 Lexus IS models on CarGurus are accident free.
The 2021 Lexus IS features a stylish design, multiple powertrain options, and great handling, making it a strong contender in the compact luxury sports sedan market.
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 125,409
- Stock #:
- 102525
- VIN:
- JTHGA1D23L5102525
2020 Lexus IS
300 RWD
125,409 mi
$21,531
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black Metallic Trim
- Transmission:
- Automatic
- Mileage:
- 53,908
- Stock #:
- M5112892
- VIN:
- JTHCA1D23M5112892
2021 Lexus IS
300 RWD
53,908 mi
$32,346
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White Pearl
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 79,891
- Stock #:
- T104280
- VIN:
- JTHAA1D21L5104280
2020 Lexus IS
300 RWD
79,891 mi
$26,020
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Open-Pore Black Wood Trim
- Transmission:
- Automatic
- Mileage:
- 54,238
- Stock #:
- 22850
- VIN:
- JTHDA1D23N5119038
2022 Lexus IS
300 RWD
54,238 mi
$32,771
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Carmel W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 99,642
- Stock #:
- 3024205
- VIN:
- JTHD81F27N5049066
2022 Lexus IS
300 AWD
99,642 mi
$31,445
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Fuel type:
- Gasoline
- Interior color:
- Chateau
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 73,217
- Stock #:
- L5036780AA
- VIN:
- JTHGZ1B21L5036780
2020 Lexus IS
350 RWD
73,217 mi
$32,716
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,569
- Stock #:
- 106750
- VIN:
- JTHGA1D28L5106750
2020 Lexus IS
300 RWD
31,569 mi
$32,722
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 43,461
- Stock #:
- 039776
- VIN:
- JTHGZ1B21M5039776
2021 Lexus IS
350 F Sport RWD
43,461 mi
$40,948
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red w/Dark Gray Streamline Trim
- Transmission:
- Automatic
- Mileage:
- 68,606
- Stock #:
- 101898
- VIN:
- JTHGA1D24L5101898
2020 Lexus IS
300 RWD
68,606 mi
$27,964
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 57,436
- Stock #:
- M5042223
- VIN:
- JTHGZ1B28M5042223
2021 Lexus IS
350 F Sport RWD
57,436 mi
$38,972
CarGurus Analysis: 2021 Lexus IS
overall
Summary
With 480 currently listed for sale and an average price of $35,631.00, 29.0% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
73.8% of 2021 Lexus IS models on CarGurus are accident free.
The 2021 Lexus IS features a stylish design, multiple powertrain options, and great handling, making it a strong contender in the compact luxury sports sedan market.
Why it stands out
The 2021 Lexus IS stands out in the compact luxury sports sedan segment with its stylish design and sporty performance. It embodies a blend of luxury and athleticism, appealing to both enthusiasts and luxury buyers. The IS is equipped with multiple powertrain options, including a turbocharged four-cylinder and a V6, providing a range of performance capabilities. The car's handling is particularly praised, thanks to its well-tuned suspension and driver-focused design. While some users have noted the base engine as underwhelming and the technology as somewhat outdated, the overall driving experience and luxurious feel of the IS make it a compelling choice for buyers seeking a balance of style and performance.
Other model years to consider
- Average price: $44,278.00
- Good/great deal percentage: 35.9%
- Total listings: 1,428
- Average price: $42,059.00
- Good/great deal percentage: 35.1%
- User rating: 4.8 / 5
- Total listings: 1,266
- Average price: $38,421.00
- Good/great deal percentage: 33.0%
- User rating: 5 / 5
- Total listings: 1,006
This analysis is based on CarGurus' proprietary market data from July 6, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Chicago: The city of Chicago, IL ($38,193) has the highest average price, likely reflecting a strong demand for luxury vehicles in urban areas.
- Lowest Prices in Philadelphia: Philadelphia, PA ($31,866) offers the lowest average price, suggesting a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like Los Angeles (97 listings) and Dallas (76 listings) have substantial inventory, which may contribute to more stable pricing around the national average.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Chicago, IL | 53 | $38,193 |
| Dallas, TX | 76 | $36,101 |
| Los Angeles, CA | 97 | $36,276 |
| Houston, TX | 71 | $33,897 |
| Miami, FL | 63 | $32,014 |
| New York, NY | 68 | $32,020 |
| Philadelphia, PA | 64 | $31,866 |
| Washington, DC | 59 | $30,781 |
| Atlanta, GA | 77 | $35,483 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 300 RWD (534 listings) is the most prevalent trim, indicating strong demand for this configuration.
- Price Range Across Trims: The 350 F Sport RWD ($42,950 MSRP) is positioned significantly higher than the base 300 RWD ($39,050 MSRP), reflecting the added performance and features.
- AWD Demand: The 300 AWD (257 listings) and 350 F Sport AWD (104 listings) trims show a solid interest in all-wheel-drive options, catering to buyers in regions with varying weather conditions.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 534 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 364 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 257 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 104 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at Premium Prices: The 2026 Lexus IS is priced at $54,766, approximately 20.4% above MSRP, indicating strong demand for the latest model.
- Depreciation Trends: Older models, such as the 2014 Lexus IS, show significant depreciation, with an average price of $16,113, reflecting a decline of 55.4% from MSRP.
- Best Value Years: The 2022 Lexus IS is priced at $38,353, which is only -1.9% below MSRP, making it a compelling option for buyers seeking a nearly new vehicle.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Lexus IS | $45,500 | $54,766 | +20.4% |
| 2025 Lexus IS | $40,535 | $48,366 | +19.3% |
| 2024 Lexus IS | $40,085 | $44,892 | +12.0% |
| 2023 Lexus IS | $40,085 | $42,176 | +5.2% |
| 2022 Lexus IS | $39,125 | $38,353 | -1.9% |
| 2020 Lexus IS | $38,560 | $28,462 | -26.2% |
| 2019 Lexus IS | $38,560 | $25,577 | -33.6% |
| 2018 Lexus IS | $38,210 | $23,449 | -38.7% |
| 2017 Lexus IS | $37,825 | $20,698 | -45.3% |
| 2016 Lexus IS | $37,325 | $18,705 | -50.0% |
| 2015 Lexus IS | $36,550 | $17,720 | -51.6% |
| 2014 Lexus IS | $36,100 | $16,113 | -55.4% |
These recommendations are based on CarGurus' proprietary market data from July 9, 2026, CarGurus experts' opinions, and generative AI.
FAQs
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