Used 2021 GMC Sierra 2500HD for Sale near Ruston, LA
226 results
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 1,847 currently listed for sale and an average price of $51,224.00, 31.8% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
80.0% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and technology features, which are competitive in the heavy-duty truck segment.
CarGurus Analysis: 2021 GMC Sierra 2500HD

Summary
With 1,847 currently listed for sale and an average price of $51,224.00, 31.8% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
80.0% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and technology features, which are competitive in the heavy-duty truck segment.
Why it stands out
The 2021 GMC Sierra 2500HD distinguishes itself with a blend of rugged capability and refined comfort, embodying the "Professional Grade" philosophy of the brand. It offers many modern technology and comfort features that are often sought after in heavy-duty pickups, such as an intuitive infotainment system that includes features like Bluetooth, Apple CarPlay, and Android Auto. This model year is particularly appealing to buyers thanks to its reputation for reliability and strong performance, including a robust diesel engine option. Additionally, the Sierra 2500HD excels in providing a spacious interior and a variety of configurations that cater to different needs, making it suitable for both everyday use and heavy-duty work applications. While some competitors may boast greater towing capacities, the Sierra’s balance of comfort and usability ensures it remains a strong contender in its class.
Other model years to consider
- Average price: $77,017.00
- Good/great deal percentage: 34.0%
- User rating: 5 / 5
- Total listings: 3,200
- Average price: $49,149.00
- Good/great deal percentage: 30.9%
- User rating: 4.86 / 5
- Total listings: 1,318
- Average price: $69,900.00
- Good/great deal percentage: 34.2%
- User rating: 4 / 5
- Total listings: 3,711
This analysis is based on CarGurus' proprietary market data from April 13, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| Double Cab LB RWD | $39,000 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLE Crew Cab 4WD | $48,200 |
| SLT Crew Cab 4WD | $56,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends








