Used 2021 GMC Sierra 2500HD for Sale near Phoenix, AZ
161 results
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 87,844
- Stock #:
- NF278911
- VIN:
- 1GT49REY5NF278911


Sponsored by AutoNation Chevrolet Gilbert
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
87,844 mi
$54,497
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Green
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 63,477
- Stock #:
- MF253530W
- VIN:
- 1GT49REY2MF253530

Sponsored Listing
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
63,477 mi
$59,393
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 35,640
- Stock #:
- CS73654
- VIN:
- 1GT49PEY3NF196194

Sponsored Listing
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
35,640 mi
$60,772
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 110,539
- Stock #:
- ADR260046C
- VIN:
- 1GT19REY4MF124109

-$1,893
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
110,539 mi
$48,437
$46,544
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Red
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 175,040
- Stock #:
- 2974
- VIN:
- 1GT28ME76LF236748

2020 GMC Sierra 2500HD
175,040 mi
$19,932
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Dark Walnut/Slate
- Transmission:
- Automatic
- Mileage:
- 102,749
- Stock #:
- S792
- VIN:
- 1GT49NEY1MF281375

-$1,700
2021 GMC Sierra 2500HD
SLT Crew Cab 4WD
102,749 mi
$42,700
$41,000
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 27,745
- Stock #:
- P0269
- VIN:
- 1GT49PEY6NF234131

2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
27,745 mi
$60,982
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 96,600
- Stock #:
- 308822-TR-109
- VIN:
- 1GT49MEY2MF308822

2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
96,600 mi
$39,950
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 26,123
- Stock #:
- 11754U
- VIN:
- 1GT18LE77LF169180

-$1,295
2020 GMC Sierra 2500HD
Base Crew Cab RWD
26,123 mi
$37,315
$36,020
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Silver
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,284
- Stock #:
- G60950B
- VIN:
- 1GT49REY0LF257817

2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
59,284 mi
$57,592
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 50,535
- Stock #:
- 116057A
- VIN:
- 1GT49ME79NF268330

2022 GMC Sierra 2500HD
SLE Crew Cab 4WD
50,535 mi
$45,079
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White
- Fuel type:
- Biodiesel
- Interior color:
- Dark Walnut/Slate
- Transmission:
- Automatic
- Mileage:
- 150,177
- Stock #:
- 61917
- VIN:
- 1GT19MEY4LF168371

2020 GMC Sierra 2500HD
SLE Crew Cab 4WD
150,177 mi
$34,712
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- 6-Speed Automatic
- Mileage:
- 99,804
- Stock #:
- 4928
- VIN:
- 1GT49PE72NF177627

2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
99,804 mi
$45,668
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 154 currently listed for sale near Phoenix, AZ and an average price of $53,861.00, 18.2% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.2% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD provides a blend of comfort and advanced technology features, making it a competitive choice in the heavy-duty truck segment.
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 108,000
- Stock #:
- T3005
- VIN:
- 1GT49REY6LF104424

2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
108,000 mi
$47,222
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,997
- Stock #:
- F245994
- VIN:
- 1GT49RE73NF245994

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
45,997 mi
$54,728
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 97,493
- Stock #:
- 2025-526
- VIN:
- 1GT49ME77MF311402

2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
97,493 mi
$35,917
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- [GAZ] Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 125,950
- Stock #:
- 26219
- VIN:
- 1GT49LE72MF102479
![[GAZ] Summit White 2021 GMC Sierra 2500HD SLE Crew Cab 4WD Pickup Truck Four-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/05/05/22/51/2021_gmc_sierra_2500hd-pic-6150866528384328921-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
125,950 mi
$32,000
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Gray
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 228,013
- Stock #:
- EV195201
- VIN:
- 1GT49REY1LF195201

2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
228,013 mi
$33,698
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 87,844
- Stock #:
- NF278911
- VIN:
- 1GT49REY5NF278911

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
87,844 mi
$54,497
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Green
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 63,477
- Stock #:
- MF253530W
- VIN:
- 1GT49REY2MF253530

2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
63,477 mi
$59,393
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Exterior color:
- Black
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 120,409
- Stock #:
- 149393A
- VIN:
- 1GT49REY0NF149393

2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
120,409 mi
$47,650
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 111,761
- Stock #:
- AH201859
- VIN:
- 1GT49ME74NF201859

-$1,000
2022 GMC Sierra 2500HD
SLE Crew Cab 4WD
111,761 mi
$33,998
$32,998
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 50,436
- Stock #:
- 60088B
- VIN:
- 1GT49REY5NF298219

Sponsored Listing
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
50,436 mi
$63,248
CarGurus Analysis: 2021 GMC Sierra 2500HD

Summary
With 154 currently listed for sale near Phoenix, AZ and an average price of $53,861.00, 18.2% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
79.2% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD provides a blend of comfort and advanced technology features, making it a competitive choice in the heavy-duty truck segment.
Why it stands out
The 2021 GMC Sierra 2500HD differentiates itself with a more upscale design and finishes compared to its Chevrolet Silverado counterparts, appealing to consumers looking for both functionality and style. This heavy-duty pickup truck is equipped with contemporary technology and comfort features that enhance the driving experience. Drivers benefit from advanced safety features and an optional powerful 6.6-liter Duramax turbodiesel engine, which provides impressive towing and hauling capabilities. While the truck's pricing may be slightly higher than some of its rivals, the luxury features available in trims like the Denali make it a desirable option for those seeking more than just a work vehicle. However, prospective buyers should remain aware of reported issues across various model years, including electrical glitches and drivetrain concerns.
Other model years to consider
- Average price: $79,393.00
- Good/great deal percentage: 23.0%
- User rating: 5 / 5
- Total listings: 252
- Average price: $53,257.00
- Good/great deal percentage: 13.1%
- User rating: 4.86 / 5
- Total listings: 122
- Average price: $74,071.00
- Good/great deal percentage: 24.7%
- User rating: 4 / 5
- Total listings: 255
This analysis is based on CarGurus' proprietary market data from June 9, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB 4WD | $39,000 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLT Crew Cab 4WD | $56,200 |
| SLE Crew Cab 4WD | $48,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis: Phoenix, AZ Market Report
Pricing by Nearby Locations
Market Area: Phoenix, AZ
Key Insights
- Highest Prices in Tucson: The city of Tucson shows the highest average price at $68,495, indicating stronger demand or scarcity in that market.
- Lowest Prices in Surprise: Conversely, Surprise offers the lowest average price of $54,429, suggesting a more competitive inventory or potential over-supply.
- Price Disparity Reflects Inventory Trends: Despite Tucson having a higher average price, it shares similar inventory levels with Prescott (127 listings), indicating that local demand might drive higher prices even with comparable stock levels.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Tucson, AZ | 127 | $68,495 |
| Nogales, AZ | 120 | $63,995 |
| Casa Grande, AZ | 147 | $56,685 |
| Prescott, AZ | 127 | $56,995 |
| Apache Junction, AZ | 159 | $53,975 |
| Surprise, AZ | 160 | $54,429 |
Pricing Analysis by Model Year
Key Insights
- Price Surge for Newer Models: The 2026 GMC Sierra 2500HD is notably priced at $88,642, reflecting a premium of almost 88.8% above its original MSRP, indicative of high demand for the latest models.
- Logarithmic Depreciation: Prices show significant drops for older models; for example, the 2019 model has fallen to $42,475, a decline of -11.0% from MSRP, suggesting a clearer depreciation trend for vehicles older than five years.
- Stability in Recent Years: The latest models from 2022 and onward have retained stronger values with much smaller depreciation, particularly the 2023 model, which is only -13.5% below MSRP.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $47,000 | $88,642 | +88.8% |
| 2025 | $46,300 | $78,149 | +68.8% |
| 2024 | $45,400 | $73,042 | +60.8% |
| 2023 | $42,200 | $57,678 | +36.5% |
| 2022 | $36,200 | $54,517 | +50.6% |
| 2020 | $35,800 | $57,093 | +59.6% |
| 2019 | $38,200 | $42,475 | -11.0% |
| 2018 | $35,000 | $38,889 | +11.1% |
| 2017 | $34,190 | $46,116 | +35.0% |
| 2016 | $33,535 | $44,988 | +34.1% |
These recommendations are based on CarGurus' proprietary market data from June 11, 2026, CarGurus experts' opinions, and generative AI.