Audi A6 vs Mercedes-Benz E-Class Compare price, expert/user reviews, mpg, engines, safety, cargo capacity and other specs at a glance.

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2022 Audi A6 2.0T quattro Premium AWD
Photo of 2021 model year shown

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2021 Mercedes-Benz E-Class E 350 4MATIC Sedan AWD

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User Ranking Drivers and owners ranked these cars in 9 categories.

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Best Midsize Luxury Sedans
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#2
Best 2021 Midsize Luxury Sedans
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Based on 5 rankings.

New Car Pricing New listing price comparison and analysis.

2022 Audi A6
2.0T quattro Premium AWD
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
MSRP
$56,750
Invoice
$53,345
Average Price Paid
$57,821
48 listings nationwide

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2022 Audi A6
2.0T quattro Premium AWD
No Data Available
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
No Data Available

Expert Reviews Reviews from CarGurus experts.

2022 Audi A6
2.0T quattro Premium AWD
Stephen Edelstein Preview:

Back when Audi made just a few models, the A6 was a mid-range but upscale car that blended some of the nimble driving dynamics of the smaller A4 with some of the posh elitism of the fl...

Read full review »
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
Andrew Newton Test Drive Review:

When money is but a mild concern, a brand-new Mercedes-Benz is a reasonable purchase. The E-Class is the company's most practical and versatile car, as high-quality and necessary in a ...

Read full review »
No Data Available
No Data Available
  • Look and Feel 9
  • Performance 8
  • Form & Function 8
  • Technology 10
  • Safety 10
  • Cost-Effectiveness 5
  • Read full review »

Specs

2022 Audi A6
2.0T quattro Premium AWD
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD
Powertrain 7-Speed Dual Clutch 9-Speed Automatic
Drivetrain
AWD
AWD
Fuel Economy, City
23 MPG
22 MPG
Fuel Economy, Highway
32 MPG
30 MPG
Fuel Tank Volume 19.3 gal 17.4 gal
Engine
Fuel Type
Gasoline
Gasoline
Power
261 hp @ 5,000 RPM
255 hp @ 5,800 RPM
Torque
273 lb-ft @ 1,600 RPM
273 lb-ft @ 1,800 RPM
Cylinders
4 cylinders
4 cylinders
Compression Ratio
9.6:1
10.5:1
Displacement
2,000 cc
2,000 cc
Bore x Stroke
3.25 in x 3.65 in
3.27 in x 3.62 in
Safety
ABS Brakes Standard Standard
Driver Airbag Standard Standard
Passenger Airbag Standard Standard
Front Side Airbags Standard Standard
Rear Side Airbags Standard --
Curtain Airbags Standard Standard
NHTSA Crash Test Results
Overall 4 stars --
Front Crash Overall 4 stars --
Front Crash Driver 5 stars --
Front Crash Passenger 4 stars --
Side Crash Overall 5 stars 5 stars
Side Barrier Driver 5 stars 5 stars
Side Barrier Passenger 5 stars 5 stars
Side Pole Driver 5 stars 5 stars
Rollover 5 stars 5 stars
Comfort and Convenience
Sunroof/Moonroof Standard Standard
Leather Seats Standard --
Air Conditioning Standard Standard
Radio Standard Standard
Power Windows Standard Standard
Power Door Locks Standard Standard
Driver Power Seats Standard Standard
Passenger Power Seats Standard Standard
Interior
Maximum Seating 5 seats 5 seats
Front Legroom 41.3 in 41.7 in
Back Legroom 37.4 in 36.2 in
Payload and Towing
Cargo Volume 13.7 cu ft 13.1 cu ft
Maximum Payload 1,102 lbs --
Exterior
Length 194.4 in 194.3 in
Width 83.1 in 81.3 in
Height 57.4 in 57.8 in
Wheelbase 115.1 in 115.7 in

Available Options

2022 Audi A6
2.0T quattro Premium AWD

Exterior Colors

  • Brilliant Black
  • CHRONOS Gray Metallic
  • FLORETT Silver Metallic
  • Firmament Blue Metallic
  • Glacier White Metallic
  • Ibis White
  • Manhattan Gray Metallic
  • Mythos Black Metallic
  • Soho Brown Metallic

Option Packages

  • Black Optic Sport Package
  • Convenience Package
2021 Mercedes-Benz E-Class
E 350 4MATIC Sedan AWD

Exterior Colors

  • Black
  • Cirrus Silver Metallic
  • DESIGNO Cardinal Red Metallic
  • DESIGNO Diamond White Metallic
  • Graphite Grey Metallic
  • Lunar Blue Metallic
  • MANUFAKTUR Cardinal Red Metallic
  • MANUFAKTUR Diamond White Metallic
  • MANUFAKTUR Selenite Grey MAGNO
  • Mojave Silver Metallic
  • Obsidian Black Metallic
  • Polar White
  • Selenite Grey Metallic

Option Packages

  • Air Body Control Air Suspension
  • AMG Line Exterior
  • Acoustic Comfort Package
  • Active Multicontour Front Seats W/Massage Feature
  • DESIGNO MACCHIATO Beige/Saddle Brown Nappa Leather
  • Driver Assistance Package
  • Exterior Lighting Package
  • Head-Up Display
  • Premium Package
  • Warmth & Comfort Package
  • Wood/Leather Steering Wheel
  • MANUFAKTUR Black Piano Lacquer Trim
  • Rear Side Air Bags
  • Black, Leather Upholstery
  • Black, Nappa Leather Upholstery
  • MACCHIATO Beige/Black, Leather Upholstery
  • MACCHIATO Beige/Grey, Nappa Leather Upholstery
  • Neva Grey/Magma Grey, Leather Upholstery
  • Nut Brown/Black, Leather Upholstery
  • Nut Brown/Black, Nappa Leather Upholstery
  • Active Multicontour Front Seats W/Massage Feature
  • Heated Rear Seats
  • Panorama Roof
  • Wheels: 19" X 8.0" 10-Spoke
  • Wheels: 19" X 8.0" AMG 10-Spoke
  • Wheels: 19" X 8.0" AMG Twin 10-Spoke
  • Wheels: 19" X 8.0" AMG Twin 5-Spoke
  • Wheels: 19" X 8.0" AMG Twin 5-Spoke W/Black Accents

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