2021 Mercedes-Benz S-Class vs 2021 Nissan Altima

2021 Mercedes-Benz S-Class
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Nissan Altima
2021 Nissan Altima
$24,550MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Nissan Altima
$24,550MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP

$109,800

MSRP

$24,550

Listings

157

Listings

202

Ratings & Reviews

User Reviews
User Reviews

Expert reviews

7.5 out of 10

Expert reviews

7.2 out of 10

Pros

  • Powerful engine

  • Comfortable

  • Impressive technology

Cons

  • High price

Pros

  • All-wheel drive available

  • Multiple powertrain options

  • Wireless Apple CarPlay/Android Auto

Cons

  • All-wheel drive not available with the turbo engine

  • Stereo is lacking

2021 Mercedes-Benz S-Class Reviews Summary

The S-Class not only sits at the top of the Mercedes hierarchy in price and prestige, but it has also long served as a technological showcase. In the press release for the redesigned 2021 S-Class, Mercedes repeatedly noted the innovations—from anti-lock brakes to airbags—that were introduced on the big sedan and eventually trickled down to mainstream vehicles.

With the previous generation dating back to the 2014 model year (with a significant update for 2018), the Mercedes-Benz S-Class was in need of an update to maintain that status, and to keep pace with other full-size luxury sedans like the Audi A8, BMW 7 Series, and Lexus LS. To do that, the new S-Class gets a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork, among other features.

The 2021 S-Class launches in two configurations, both with 4Matic all-wheel drive (AWD) and EQ Boost mild-hybrid systems. The S500 4Matic has a six-cylinder engine, while the S580 4Matic has a V8. We spent a few days with the Mercedes-Benz S580 for this review. A Mercedes-Maybach S680 4Matic version will follow in the first half of 2022, and you can expect a new AMG performance version sometime in the future as well.

2021 Nissan Altima Reviews Summary

The 2021 Nissan Altima is a popular midsize sedan now in the third year of its sixth generation of production. The Altima debuted as a 1993 model and has spent the decades nudged from the spotlight by the Toyota Camry and Honda Accord, despite continuous evolution and improvement over the years. Don’t feel bad for the Altima—it has a lot of fans, and some innovative features it hopes will allow it to take center stage someday.
No video found

Popular Features & Specs

Engine

3.0L 429 hp I6

Engine

2.5L 182 hp I4

Drive Train

AWD

Drive Train

FWD

Seating Capacity

5

Seating Capacity

5

Horsepower

429 hp @ 6100 rpm

Horsepower

182 hp @ 6000 rpm

MPG City

20

MPG City

28

MPG Highway

29

MPG Highway

39
2021 Mercedes-Benz S-Class
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Nissan Altima
2021 Nissan Altima
$24,550MSRP
Overview
Overview
OverviewShop Now
2021 Mercedes-Benz S-Class
$109,800MSRP
Overview
Overview
OverviewShop Now
2021 Nissan Altima
$24,550MSRP
Overview
Overview
OverviewShop Now

Overview

MSRP
$109,800
$24,550
Listings

Ratings & Reviews

User reviews

4.0

4.9

Expert reviews

7.5 out of 10

Read full review

7.2 out of 10

Read full review
Pros & cons

Pros

  • Powerful engine

  • Comfortable

  • Impressive technology

Cons

  • High price

Pros

  • All-wheel drive available

  • Multiple powertrain options

  • Wireless Apple CarPlay/Android Auto

Cons

  • All-wheel drive not available with the turbo engine

  • Stereo is lacking

Summary

The S-Class not only sits at the top of the Mercedes hierarchy in price and prestige, but it has also long served as a technological showcase. In the press release for the redesigned 2021 S-Class, Mercedes repeatedly noted the innovations—from anti-lock brakes to airbags—that were introduced on the big sedan and eventually trickled down to mainstream vehicles.

With the previous generation dating back to the 2014 model year (with a significant update for 2018), the Mercedes-Benz S-Class was in need of an update to maintain that status, and to keep pace with other full-size luxury sedans like the Audi A8, BMW 7 Series, and Lexus LS. To do that, the new S-Class gets a more sophisticated infotainment system, new powertrains, and more aerodynamic bodywork, among other features.

The 2021 S-Class launches in two configurations, both with 4Matic all-wheel drive (AWD) and EQ Boost mild-hybrid systems. The S500 4Matic has a six-cylinder engine, while the S580 4Matic has a V8. We spent a few days with the Mercedes-Benz S580 for this review. A Mercedes-Maybach S680 4Matic version will follow in the first half of 2022, and you can expect a new AMG performance version sometime in the future as well.

The 2021 Nissan Altima is a popular midsize sedan now in the third year of its sixth generation of production. The Altima debuted as a 1993 model and has spent the decades nudged from the spotlight by the Toyota Camry and Honda Accord, despite continuous evolution and improvement over the years. Don’t feel bad for the Altima—it has a lot of fans, and some innovative features it hopes will allow it to take center stage someday.
Video
No video found

Popular Features & Specs

Engine
3.0L 429 hp I6
2.5L 182 hp I4
Drive Train
AWD
FWD
Seating Capacity
5
5
Horsepower
429 hp @ 6100 rpm
182 hp @ 6000 rpm
MPG City
20
28
MPG Highway
29
39
Look and feel

2021 Mercedes-Benz S-Class

7/10

2021 Nissan Altima

6/10

The 2021 Mercedes-Benz S-Class retained a familiar exterior design, yet its aerodynamic efficiency was notable, boasting a drag coefficient of 0.22. This model was slightly larger than its predecessor, with increased length, wheelbase, height, and width. The classic Mercedes hood ornament and grille added a touch of luxury, complemented by standard 19-inch wheels, with options for 20-inch and 21-inch wheels. Inside, the S-Class focused on a minimalist design centered around a prominent infotainment touchscreen and digital instrument cluster. The interior featured ambient lighting with 250 LED elements and high-quality materials like Nappa leather and open-pore wood trim. However, the piano-black trim was prone to smudging and glare.

The 2021 Nissan Altima showcased a strong family identity with its V-Motion grille, available in chrome or dark chrome. Its sleek, aerodynamic profile was enhanced by a sloping roofline and modern features like LED lighting and a range of wheel options from 16-inch steel to 19-inch alloy. Despite a slightly old-fashioned stance, the Altima's fit and finish were exceptional, with deep paint and rich chrome details. The interior was intelligently laid out, with a standard 8-inch touchscreen and a cowl-shrouded instrument panel for easy readability. Higher trims offered improved materials and features, making the Altima a comfortable and practical choice.

Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Picture of 2021 Mercedes-Benz S-Class
Performance

2021 Mercedes-Benz S-Class

9/10

2021 Nissan Altima

7/10

The 2021 Mercedes-Benz S-Class offered two engine options: the S500 4Matic with a 3.0-liter turbocharged inline-six producing 429 horsepower and 384 pound-feet of torque, and the S580 4Matic with a 4.0-liter twin-turbo V8 delivering 496 hp and 516 lb-ft of torque. Both models featured a nine-speed automatic transmission and EQ Boost, a mild-hybrid system providing additional power and efficiency. The S500 accelerated from 0 to 60 mph in 4.8 seconds, while the S580 achieved it in 4.4 seconds, with top speeds limited to 130 mph. The S-Class included standard air suspension and optional E-Active Body Control, along with rear-wheel steering for improved maneuverability. Despite some wind noise at high speeds, the S-Class maintained composure on twisty roads, with precise steering and effective driving modes.

The 2021 Nissan Altima offered a choice between a 2.5-liter four-cylinder engine with 182 horsepower and 178 pound-feet of torque, and a VC-Turbo engine exclusive to the SR VC-Turbo trim. The 2.5-liter engine, paired with a CVT, provided respectable performance and fuel economy, with FWD and AWD options. The VC-Turbo, a 2.0-liter turbocharged engine with 248 hp and 273 lb-ft of torque, offered a more engaging driving experience. The Altima's suspension and steering provided decent feedback, with the VC-Turbo's sport-tuned suspension adding a touch of excitement. Despite the weight difference, the VC-Turbo was a lively performer, making the Altima a versatile choice for various driving preferences.

Form and function

2021 Mercedes-Benz S-Class

8/10

2021 Nissan Altima

8/10

The 2021 Mercedes-Benz S-Class offered increased front and rear headroom, as well as more rear legroom compared to its predecessor. While front legroom was limited, shoulder room was segment-leading, enhancing the sense of spaciousness. Cargo space increased to 12.9 cubic feet, though still less than some competitors. The S-Class featured luxurious front seats with 19 motors for adjustment, heating, ventilation, and massage functions. The interior offered ample storage, with a large center console and wireless phone charger. Rear-seat passengers enjoyed a spacious console and optional power-adjustable seats with the Executive Line package, making the S-Class suitable for chauffeur service.

The 2021 Nissan Altima featured Nissan’s Zero Gravity front seats, praised for their comfort on long drives. Upper trims offered power adjustment, memory, leather, and heating. The front cabin included ample storage, with a large glovebox, center console, and door pockets. The second row provided room for two adults, with a 60/40 split-folding design for trunk access. The Altima's trunk offered 15.4 cubic feet of space, accommodating various cargo needs.

Technology

2021 Mercedes-Benz S-Class

9/10

2021 Nissan Altima

7/10

The 2021 Mercedes-Benz S-Class came equipped with a 12.3-inch digital instrument cluster and a 12.8-inch OLED central touchscreen, supporting wireless Apple CarPlay and Android Auto. The MBUX infotainment system offered increased computing power and touchscreen reliance, with functions like climate control and seat massagers integrated into the screen. The S-Class also featured an augmented-reality head-up display and a 30-speaker Burmester audio system. While some tech features were well-executed, others, like the steering-wheel touchpads, were less intuitive. The S-Class allowed for personal profiles with biometric access and rear-seat navigation input, enhancing the luxury experience.

The 2021 Nissan Altima included standard tech features like Nissan Intelligent Key, remote engine start, Bluetooth, and more. Apple CarPlay and Android Auto were standard on most trims, with a 7-inch or 8-inch touchscreen depending on the model. Higher trims offered additional USB ports, SiriusXM satellite radio, and a Bose audio system. The Altima also featured Nissan Door to Door Navigation and NissanConnect Services, providing a comprehensive tech package for a midsize sedan.

Safety

2021 Mercedes-Benz S-Class

7/10

2021 Nissan Altima

9/10

The 2021 Mercedes-Benz S-Class lacked crash-test ratings from NHTSA and IIHS but included numerous safety features, such as a rear-passenger airbag and a suite of driver-assist technologies. These included adaptive cruise control, lane centering, automatic emergency braking, and more. Mercedes claimed improvements in these systems, with features like traffic-sign recognition and lane-keep assist offering enhanced functionality. The S-Class' driver-assist tech performed well, handling highway curves and traffic changes smoothly.

The 2021 Nissan Altima featured Nissan Safety Shield 360, standard on SV and above, with automatic emergency braking, rear cross-traffic alert, blind-spot warning, and more. ProPilot Assist, available on higher trims, offered highway driving assistance, including adaptive cruise control and lane intervention. The Altima also offered an Intelligent Around View Monitor for easier parking. The Altima received a five-star overall safety rating from NHTSA and a Top Safety Pick + rating from IIHS, highlighting its strong safety credentials.

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz S-Class is 7.5 out of 10, while the 2021 Nissan Altima scores 7.2 out of 10. Based on these ratings, the Mercedes-Benz S-Class is recommended for those seeking a luxurious and technologically advanced vehicle, while the Nissan Altima offers a practical and safe choice for everyday driving.

Choose the 2021 Mercedes-Benz S-Class if:

7.5of 10overall
  • You prioritize luxury and advanced technology features.
  • You desire a spacious and comfortable interior with high-quality materials.
  • You value a smooth and composed driving experience with powerful engine options.
157 results
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Choose the 2021 Nissan Altima if:

7.2of 10overall
  • You seek a reliable and fuel-efficient midsize sedan with modern styling.
  • You want a comfortable and practical interior with ample storage and seating space.
  • You appreciate comprehensive safety features and strong safety ratings.
202 results
See all

CarGurus highlights

Winning Vehicle Image

According to CarGurus experts, the overall rating for the 2021 Mercedes-Benz S-Class is 7.5 out of 10, while the 2021 Nissan Altima scores 7.2 out of 10. Based on these ratings, the Mercedes-Benz S-Class is recommended for those seeking a luxurious and technologically advanced vehicle, while the Nissan Altima offers a practical and safe choice for everyday driving.

Choose the 2021 Mercedes-Benz S-Class if:

Shop Now
7.5of 10overall
  • You prioritize luxury and advanced technology features.
  • You desire a spacious and comfortable interior with high-quality materials.
  • You value a smooth and composed driving experience with powerful engine options.
157 results

Choose the 2021 Nissan Altima if:

Shop Now
7.2of 10overall
  • You seek a reliable and fuel-efficient midsize sedan with modern styling.
  • You want a comfortable and practical interior with ample storage and seating space.
  • You appreciate comprehensive safety features and strong safety ratings.
202 results

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By: CarGurus + AI

At CarGurus, our team of experienced automotive writers remain at the heart of our content operation, conducting hands-on car tests and writing insightful guides that are backed by years of industry experience. To complement this, we are harnessing AI to make our content offering more diverse and more helpful to shoppers than ever. To achieve this, our AI systems are based exclusively on CarGurus content, ratings and data, so that what we produce is both unique to CarGurus, and uniquely helpful to car shoppers.

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