Used Lexus IS for Sale near Orangeburg, SC
391 results
- Year:
- 2010
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 204 hp 2.5L V6
- Exterior color:
- Smoky Granite Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 121,168
- Stock #:
- PM13517C
- VIN:
- JTHCF5C22A2034399


Sponsored by Mazda of Columbia
2010 Lexus IS
250 Sedan AWD
121,168 mi
$11,148
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Mileage:
- 73,014
- Stock #:
- L36044B
- VIN:
- JTHA81F25N5047772

Sponsored Listing
2022 Lexus IS
300 AWD
73,014 mi
$34,084
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 43,396
- Stock #:
- ZP5127439
- VIN:
- JTHCA1D28P5127439

Sponsored Listing
2023 Lexus IS
300 RWD
43,396 mi
$35,669
- Year:
- 2010
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 204 hp 2.5L V6
- Exterior color:
- Smoky Granite Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 121,168
- Stock #:
- PM13517C
- VIN:
- JTHCF5C22A2034399

2010 Lexus IS
250 Sedan AWD
121,168 mi
$11,148
- Year:
- 2025
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red (BURGUNDY)
- Transmission:
- Automatic
- Mileage:
- 6,318
- Stock #:
- 28589296
- VIN:
- JTHBZ1B24S5084718

2025 Lexus IS
350 F SPORT Design RWD
6,318 mi
$46,097
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Iridium
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Mileage:
- 85,070
- Stock #:
- V5818A
- VIN:
- JTHDA1D23N5122196

2022 Lexus IS
300 RWD
85,070 mi
$31,171
- Year:
- 2016
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 112,450
- Stock #:
- G5025394
- VIN:
- JTHBA1D21G5025394

2016 Lexus IS
200t RWD
112,450 mi
$16,904
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Mileage:
- 73,014
- Stock #:
- L36044B
- VIN:
- JTHA81F25N5047772

2022 Lexus IS
300 AWD
73,014 mi
$34,084
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 28,553
- Stock #:
- BA2860
- VIN:
- JTHGZ1B23P5064134
2023 Lexus IS
350 F SPORT RWD
28,553 mi
$44,788
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 39,704
- Stock #:
- K4519
- VIN:
- JTHGZ1B29N5050669

-$847
2022 Lexus IS
350 F Sport RWD
39,704 mi
$39,336
$38,489
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Mileage:
- 73,012
- Stock #:
- L5106890
- VIN:
- JTHAA1D25L5106890

2020 Lexus IS
300 RWD
73,012 mi
$25,723
- Year:
- 2018
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 80,049
- Stock #:
- 5075839
- VIN:
- JTHBA1D20J5075839

2018 Lexus IS
300 RWD
80,049 mi
$19,022
- Year:
- 2019
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 49,403
- Stock #:
- 25206
- VIN:
- JTHBA1D27K5090372

2019 Lexus IS
300 RWD
49,403 mi
$24,974
Recommended model year:
2022 Lexus IS
Shop 2022 Lexus IS »With 983 currently listed for sale and an average price of $38,352, 33.9% of 2022 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident free.
The 2022 Lexus IS impresses with a powerful V6 engine and offers all-wheel drive for an enhanced driving experience.
- Year:
- 2017
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Red
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 123,399
- Stock #:
- 28047189
- VIN:
- JTHBA1D28H5040671

2017 Lexus IS
200t RWD
123,399 mi
$19,397
- Year:
- 2015
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 204 hp 2.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 103,599
- Stock #:
- 70049969
- VIN:
- JTHCF1D25F5027900

2015 Lexus IS
250 Sedan AWD
103,599 mi
$20,547
- Year:
- 2018
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 65,281
- Stock #:
- 70083545
- VIN:
- JTHBA1D27J5077653

2018 Lexus IS
300 RWD
65,281 mi
$25,997
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 50,662
- Stock #:
- L5036997
- VIN:
- JTHGZ1B24L5036997

-$1,000
2020 Lexus IS
350 RWD
50,662 mi
$33,937
$32,936
- Year:
- 2025
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Carmel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 10,027
- Stock #:
- AB277
- VIN:
- JTHBZ1B29S5086240

2025 Lexus IS
350 F SPORT Design RWD
10,027 mi
$44,290
- Year:
- 2016
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Silver Lining Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- Automatic
- Mileage:
- 87,787
- Stock #:
- 016016
- VIN:
- JTHBA1D21G5016016

2016 Lexus IS
200t RWD
87,787 mi
$19,914
- Year:
- 2018
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 75,572
- Stock #:
- J5027949
- VIN:
- JTHC81D29J5027949

2018 Lexus IS
300 AWD
75,572 mi
$22,681
- Year:
- 2013
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 204 hp 2.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 114,837
- Stock #:
- 063199
- VIN:
- JTHCF5C23D5063199

2013 Lexus IS
250 Sedan AWD
114,837 mi
$14,089
- Year:
- 2018
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 89,656
- Stock #:
- 078884
- VIN:
- JTHBA1D29J5078884

2018 Lexus IS
300 RWD
89,656 mi
$23,624
- Year:
- 2023
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 35,097
- Stock #:
- AP5069815
- VIN:
- JTHGZ1B28P5069815

Sponsored Listing
2023 Lexus IS
350 F SPORT RWD
35,097 mi
$43,300
FAQs
How much does the Lexus IS cost in Orangeburg, SC?
How many Lexus IS vehicles in Orangeburg, SC have no reported accidents or damage?
What fuel types are available?
4.7 Overall rating
Customers say
The Lexus IS series is well-loved for its sporty design, smooth handling, and luxurious interiors. Owners frequently praise the car's balance of performance and comfort, alongside reliability and excellent build quality. However, some drivers express concerns about limited rear passenger space and subpar fuel economy in certain models. Overall, the Lexus IS is seen as a stylish and fun-to-drive option within the luxury sedan market.
AI generated from the text of customer reviews.
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What people say
Tarius M
Reviewed a 2015 Lexus IS on Jan 21, 2026
Great car with a great design. It will last for 300,000 miles if matainance is kept.
William A
Reviewed a 2023 Lexus 350 F SPORT RWD on Sep 24, 2024
Perfect sporty looking and driving car with longevity in mind!
Jessica C
Reviewed a 2022 Lexus IS on Mar 6, 2025
Absolutely love this car. Quiet, luxurious and classy. Has enough power. Only downfall is gas mileage.
Joseph V
Reviewed a 2023 Lexus 350 F SPORT AWD on Jan 27, 2025
Car is immaculate, runs smooth, beautiful interior, love the body exterior
Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $49,950 |
| 350 F Sport Design AWD | $47,500 |
| 350 F Sport 2 AWD | -- |
| 350 F Sport 3 AWD | -- |
| 350 F Sport RWD | $47,950 |
| 350 F Sport Design RWD | $45,500 |
| 350 Special Appearance Package AWD | -- |
Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of Lexus IS prices has changed over time.
See more price trendsCarGurus recommends the 2022 Lexus IS

Summary
With 983 currently listed for sale and an average price of $38,352, 33.9% of 2022 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus IS 5 / 5 stars.
82.5% of 2022 Lexus IS models on CarGurus are accident free.
The 2022 Lexus IS impresses with a powerful V6 engine and offers all-wheel drive for an enhanced driving experience.
Why it stands out
The 2022 Lexus IS stands out for its luxurious feel and compelling performance, particularly with its powerful V6 engine that delivers a thrilling driving experience. With its all-wheel drive capability, the IS is not only fun to drive but also reliable in varying weather conditions. Its refined interior and advanced technology features, including a user-friendly touchscreen infotainment system, make it a top choice for buyers seeking both comfort and functionality. Moreover, the safety technology incorporated in the IS provides peace of mind on the road, making it a strong contender in the luxury sedan market.
Other model years to consider
- Average price: $44,144
- Good/great deal percentage: 36.3%
- Total listings: 1,337
- Average price: $42,156
- Good/great deal percentage: 34.7%
- User rating: 4.8 / 5
- Total listings: 1,219
- Average price: $17,714
- Good/great deal percentage: 31.8%
- User rating: 4.56 / 5
- Total listings: 762
These recommendations are based on CarGurus' proprietary market data from June 22, 2026, CarGurus experts' opinions, and generative AI.
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