Used 2025 Mercedes-Benz S-Class for Sale near Iowa

Compare 2025 Mercedes-Benz S-Class Trims

The S-Class lineup offers a range of luxury options, from the budget-friendly S 500 4MATIC to the high-performance AMG S 63 E Performance 4MATIC.

• Starting at $86,352
• Best MPG/MPGe: 59 city / 70 hwy
• Most Popular: S 580 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

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Trim Deep Dives

S 500 4MATIC — "Who It's For"

The S 500 4MATIC is the pick for shoppers who want luxury features without stepping up to higher-priced trims. It's the most budget-friendly option in the lineup.

• Avg. market price: $86,352 (updated weekly)
• MPG/MPGe: 21 city / 31 hwy
• Inventory: 45 listings — lower availability; may limit negotiating room
• View S 500 4MATIC listings

S 580e 4MATIC — "Who It's For"

The S 580e 4MATIC is the pick for shoppers who want a blend of luxury and fuel efficiency without compromising on performance.

• Avg. market price: $94,959 (updated weekly)
• MPG/MPGe: 59 city / 70 hwy
• Inventory: 31 listings — lower availability; may limit negotiating room
• View S 580e 4MATIC listings

S 580 4MATIC — "Who It's For"

The S 580 4MATIC is the pick for shoppers who want a powerful luxury sedan with advanced features. It's the most popular trim in the lineup.

• Avg. market price: $105,748 (updated weekly)
• MPG/MPGe: 17 city / 25 hwy
• Inventory: 223 listings
• View S 580 4MATIC listings

AMG S 63 E Performance 4MATIC — "Who It's For"

The AMG S 63 E Performance 4MATIC is the pick for shoppers who want top-tier performance and luxury without compromise.

• Avg. market price: $150,288 (updated weekly)
• MPG/MPGe: 46 city / 53 hwy
• Inventory: 143 listings — lower availability; may limit negotiating room
• View AMG S 63 E Performance 4MATIC listings

Maybach S 580 4MATIC — "Who It's For"

The Maybach S 580 4MATIC is the pick for shoppers who want the ultimate in luxury without stepping up to the highest price point.

• Avg. market price: $192,000 (updated weekly)
• MPG/MPGe: 16 city / 27 hwy
• Inventory: 37 listings — lower availability; may limit negotiating room
• View Maybach S 580 4MATIC listings

Maybach S 680 4MATIC — "Who It's For"

The Maybach S 680 4MATIC is the pick for shoppers who want the pinnacle of luxury and performance in a sedan.

• Avg. market price: $224,342 (updated weekly)
• MPG/MPGe: 12 city / 20 hwy
• Inventory: 33 listings — lower availability; may limit negotiating room
• View Maybach S 680 4MATIC listings

Trim Recommendations

Most Popular — S 580 4MATIC

With 223 active listings, the S 580 4MATIC is the clear volume leader in the lineup.

Browse S 580 4MATIC listings

Best Budget Option — S 500 4MATIC

At $86,352 avg market price — below the lineup median of $128,018 — it's the most accessible entry point.

Browse S 500 4MATIC listings

Best for Fuel Economy — S 580e 4MATIC

With an impressive 59 city / 70 hwy MPG, the S 580e 4MATIC leads the lineup in fuel efficiency.

Browse S 580e 4MATIC listings

These recommendations are based on CarGurus' proprietary market data from September 24, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2025 Mercedes-Benz S-Class cost?

Prices have softened 11.05% compared to this time last year, making it a favorable time to shop this model year.

There are 495 listings available, which suggests you should have a workable range of choices.

Is the 2025 Mercedes-Benz S-Class a good car?

Yes — the 2025 Mercedes-Benz S-Class earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Performance at 9/10.

It’s a flagship luxury sedan that aims to deliver comfort, performance, technology, and refinement in equal measure, and it does so with a comfortable ride and premium interior materials. The trade-offs are limited cargo space and frustrating capacitive touch controls, so it suits you best if you want a deeply polished, highly configurable luxury sedan and can live with some interface annoyance.

29.3% of listings are priced as good or great deals, so there is some room to shop selectively.

Is the 2025 Mercedes-Benz S-Class reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The S-Class is described as a benchmark luxury sedan with a strong safety record and a cabin that feels exceptionally well built, with no detectable creaks or squeaks in testing. Its performance side is also polished, with smooth power delivery and a civilized driving experience that supports the impression of careful engineering.

The plug-in hybrid and mild-hybrid powertrains add complexity, so used buyers should pay close attention to charging behavior, electrical-system operation, and overall maintenance history.

What should I look for when buying a used 2025 Mercedes-Benz S-Class?

Accident-free inventory is excellent at 96.8% — clean inventory, standard diligence applies.

You should still run a history report and prioritize a pre-purchase inspection, especially on a car with this much technology and this many available powertrains. Focus on the condition of the infotainment controls, driver-assistance systems, and any hybrid-specific components if you’re considering a plug-in model.

Key things to evaluate:

• Trim level: The S-Class is offered in multiple configurations, and the base setup already brings a very upscale cabin with premium materials, a striking dashboard layout, and a long-wheelbase body in the U.S. Higher trims add rear-seat amenities and more luxury hardware, so the best choice depends on whether you care more about front-seat comfort or executive-style rear seating.
• Powertrain: You can choose from a turbocharged inline-six, a twin-turbo V8, a plug-in hybrid with an electric motor and 22.7-kWh battery pack, or the AMG S 63 E Performance plug-in hybrid. The lineup emphasizes smooth, strong acceleration, and the plug-in hybrid is the efficiency leader with 48 miles of electric range and 23 mpg combined once the battery is depleted.
• Safety package: Standard advanced safety features include forward collision warning with automatic emergency braking, adaptive cruise control, blind-spot monitoring with rear cross-traffic alert, lane-keep assist, automated lane-change assist, evasive steering assistance, automatic reverse braking, a semi-automated parking system, and a surround-view camera system. The Pinnacle trim adds rear-seat side and seatbelt airbags.
• Infotainment: Every model gets a 12.3-inch digital instrument panel, a 12.8-inch infotainment touchscreen, native navigation with augmented reality video overlays, voice recognition, and a Burmester surround-sound system. The Pinnacle trim adds rear-seat tech, including an infotainment-system tablet, voice controls, a wireless charging pad, and dual 11.6-inch displays.
• Fuel efficiency: The S 580e is rated at 48 miles of electric range and 23 mpg combined after the battery is depleted. The S 500 is rated at 24 mpg combined, the S 580 at 20 mpg, and the AMG S 63 E Performance at 16 miles of electric range and 18 mpg under hybrid power.

Which 2025 Mercedes-Benz S-Class trim should I buy?

The 2025 Mercedes-Benz S-Class is offered in 4 trim levels: S 500, S 580, S 580e, AMG S 63 E Performance.

Here's the short version:

• S 500: This is the entry point, but it still gives you the core S-Class experience with a turbocharged inline-six, standard all-wheel drive, and the full luxury-sedan atmosphere. It’s the best-value trim if you want the S-Class badge and comfort without paying for extra power you may not need.
• S 580: This trim upgrades you to a twin-turbo V8 with more power and stronger straight-line performance, while keeping the same overall luxury mission. Choose it if you want a more effortless feel and are willing to pay for the extra performance.
• S 580e: This plug-in hybrid is the efficiency leader and also brings strong output, making it the most balanced choice for many shoppers who can charge at home. It’s the best-value trim if you want the broadest mix of power, efficiency, and everyday usability.
• AMG S 63 E Performance: This is the performance flagship, pairing a V8 with an electric motor for very serious output and quick acceleration. Buy it if you want the most extreme version of the S-Class and are shopping for performance first.

The Pinnacle trim adds rear-seat amenities and rear-seat side and seatbelt airbags.

Is now a good time to buy a used 2025 Mercedes-Benz S-Class?

The market looks selective rather than overheated, so you can shop with some leverage if you’re patient.

• Deal availability: 29.3% of listings are priced as good or great deals.
• Inventory: There are 495 listings available.
• Price trend: Prices have softened 11.05% compared with last year.
• Clean inventory: 96.8% of listings are accident-free.

If you find a listing below $123,905, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2025 Mercedes-Benz S-Class's resale value?

The current average of $123,959 sits slightly below last year's $139,360.

That price movement suggests the market has cooled, which can help you buy more favorably now but may also mean future resale values depend heavily on condition and equipment. If you’re planning to sell later, a well-kept example with desirable features should stand out more than a neglected one, especially in a luxury segment where buyers expect a high standard.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2025 Mercedes-Benz S-Class safe?

It earns a 7/10 safety score from our experts.

Standard advanced safety features include forward collision warning with automatic emergency braking, adaptive cruise control, blind-spot monitoring with rear cross-traffic alert, lane-keep assist, automated lane-change assist, evasive steering assistance, automatic reverse braking, a semi-automated parking system, and a surround-view camera system. The Pinnacle trim adds rear-seat side and seatbelt airbags.

Crash test results have not been published for this generation yet, so you should lean more heavily on the standard equipment list and the car’s strong in-testing behavior of its driver-assistance systems. The adaptive cruise control is especially strong, with smooth transitions between acceleration and braking.

Should I buy a 2025 Mercedes-Benz S-Class or consider a different year?

If you're weighing the 2025 against nearby model years, here's how to think about it:

Choose the 2025 if:

• 29.3% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 96.8% — clean inventory, standard diligence applies.
• Price trend: Prices have softened 11.05% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• The 2025 model adds newly standard digital key functionality and a center airbag, plus wider availability of the AMG Line trim package.

The bottom line: If you want the freshest version of this flagship sedan with the latest standard equipment and a softer market, the 2025 is the one to target. If you’re mainly chasing the lowest possible price, a nearby model year may be worth comparing, but the 2025 gives you a strong mix of value, features, and inventory choice.

These recommendations are based on CarGurus' proprietary market data from September 22, 2026, CarGurus experts' opinions, and generative AI.