Used 2025 Mercedes-Benz S-Class for Sale nearFort Myers, FL

Compare 2025 Mercedes-Benz S-Class Trims

The S-Class lineup offers a range of luxury options, from the budget-friendly S 500 4MATIC to the high-performance AMG S 63 E Performance 4MATIC.

• Starting at $86,406
• Best MPG/MPGe: 59 city / 70 hwy
• Most Popular: S 580 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

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Trim Deep Dives

S 500 4MATIC — "Who It's For"

The S 500 4MATIC is the pick for shoppers who want luxury features without stepping up to higher price points. It offers a solid balance of performance and comfort.

• Avg. market price: $86,406 (updated weekly)
• MPG/MPGe: 21 city / 31 hwy
• Inventory: 41 listings — lower availability; may limit negotiating room
• View S 500 4MATIC listings

S 580e 4MATIC — "Who It's For"

The S 580e 4MATIC is the pick for shoppers who want a luxury hybrid experience without sacrificing performance. It's also one of the most fuel-efficient trims.

• Avg. market price: $98,767 (updated weekly)
• MPG/MPGe: 59 city / 70 hwy
• Inventory: 30 listings — lower availability; may limit negotiating room
• View S 580e 4MATIC listings

S 580 4MATIC — "Who It's For"

The S 580 4MATIC is the pick for shoppers who want a blend of luxury and performance without going for the highest price. It's the most popular trim in the lineup.

• Avg. market price: $105,817 (updated weekly)
• MPG/MPGe: 17 city / 25 hwy
• Inventory: 210 listings
• View S 580 4MATIC listings

AMG S 63 E Performance 4MATIC — "Who It's For"

The AMG S 63 E Performance 4MATIC is the pick for shoppers who want top-tier performance and luxury features. It's designed for those who crave speed and style.

• Avg. market price: $157,757 (updated weekly)
• MPG/MPGe: 46 city / 53 hwy
• Inventory: 136 listings — lower availability; may limit negotiating room
• View AMG S 63 E Performance 4MATIC listings

Maybach S 580 4MATIC — "Who It's For"

The Maybach S 580 4MATIC is the pick for shoppers who want the ultimate in luxury without the highest price tag. It offers a lavish experience with advanced features.

• Avg. market price: $177,850 (updated weekly)
• MPG/MPGe: 16 city / 27 hwy
• Inventory: 36 listings — lower availability; may limit negotiating room
• View Maybach S 580 4MATIC listings

Maybach S 680 4MATIC — "Who It's For"

The Maybach S 680 4MATIC is the pick for shoppers who want the pinnacle of luxury and performance. It features a powerful V12 engine and unmatched comfort.

• Avg. market price: $224,899 (updated weekly)
• MPG/MPGe: 12 city / 20 hwy
• Inventory: 39 listings — lower availability; may limit negotiating room
• View Maybach S 680 4MATIC listings

Trim Recommendations

Most Popular — S 580 4MATIC

With 210 active listings, the S 580 4MATIC is the clear volume leader in the lineup.

Browse S 580 4MATIC listings

Best Budget Option — S 500 4MATIC

At $86,406 avg market price — below the lineup median of $131,787 — it's the most accessible entry point.

Browse S 500 4MATIC listings

Best for Fuel Economy — S 580e 4MATIC

The S 580e 4MATIC offers impressive fuel efficiency with 59 city / 70 hwy MPG/MPGe.

Browse S 580e 4MATIC listings

These recommendations are based on CarGurus' proprietary market data from September 2, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2025 Mercedes-Benz S-Class cost?

Prices have softened 11.21% compared to this time last year, making it a favorable time to shop this model year.

There are 477 listings available, which gives you a meaningful amount of inventory to compare.

If you find a listing below $126,982.95, that's toward the low end of the year-round range and worth acting on quickly.

Is the 2025 Mercedes-Benz S-Class a good car?

Yes — the 2025 Mercedes-Benz S-Class earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Performance at 9/10.

The S-Class is positioned as a flagship luxury sedan built around comfort, performance, technology, and refinement, and it leans hard into premium execution. The cabin uses premium interior materials, and the car’s mission is to deliver the kind of luxury that is difficult to beat.

The trade-offs are clear: it does not have much cargo space, and its capacitive touch controls can be frustrating. Even so, the S-Class still fits buyers who want a highly tailored luxury experience with multiple powertrain options.

With 27.0% of listings marked as good or great deals, the market gives you some room to shop selectively.

Is the 2025 Mercedes-Benz S-Class reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The S-Class is described as a benchmark luxury sedan, and Mercedes’ construction is presented as exceptionally solid, with no detectable creaks or squeaks in the cabin. The driving experience is also described as smooth, quiet, and highly civilized, which supports the impression of a well-executed flagship.

Its performance hardware is broad and polished, with multiple powertrain choices and a power delivery that is described as buttery smooth and incredibly linear. The plug-in hybrid version also adds strong electric range and seamless transitions between electric and gas power.

If you plan to own one used, your biggest long-term risk is not basic execution but complexity: this is a highly sophisticated luxury sedan, so condition, maintenance history, and electronics behavior matter a lot.

What should I look for when buying a used 2025 Mercedes-Benz S-Class?

Accident-free inventory is excellent at 95.8% — clean inventory, standard diligence applies.

You should still run a history report and prioritize a pre-purchase inspection, especially on a car with this much technology and luxury equipment. Focus on cabin condition, control operation, and whether the features you care about work as intended, since the S-Class is built around a lot of high-end systems.

Key things to evaluate:

• Trim level: The cabin is defined by premium materials, a striking horizontal dashboard layout, and a formal luxury feel, but the digital displays can look less integrated than the rest of the interior. The base setup already emphasizes luxury, while higher trims add more rear-seat amenities.
• Powertrain: The lineup includes a turbocharged 3.0-liter inline-six, a twin-turbo 4.0-liter V8, and plug-in hybrid variants. The plug-in hybrid is the efficiency leader, with 48 miles of electric range and 23 mpg combined once the battery is depleted.
• Safety package: Standard advanced safety features include forward collision warning with automatic emergency braking, adaptive cruise control, blind-spot monitoring with rear cross-traffic alert, lane-keep assist, automated lane-change assist, evasive steering assistance, automatic reverse braking, a semi-automated parking system, and a surround-view camera system. The Pinnacle trim adds rear-seat side and seatbelt airbags.
• Infotainment: All models have a 12.3-inch digital instrument panel, a 12.8-inch infotainment touchscreen, native navigation with augmented reality video overlays, voice recognition, and a Burmester surround-sound system. A digital key feature is standard, and the Pinnacle trim adds rear-seat tech and charging features.
• Fuel efficiency: The S 580e is rated at 23 mpg combined after the battery is depleted, while the S 500 is rated at 24 mpg combined and the S 580 at 20 mpg combined.

Which 2025 Mercedes-Benz S-Class trim should I buy?

The 2025 Mercedes-Benz S-Class is offered in 4 trim levels: S 500, S 580, S 580e, AMG S 63 E Performance.

Here's the short version:

• S 500: This is the entry point, and it gives you the core S-Class experience with the turbocharged inline-six, standard all-wheel drive, and the full luxury-tech baseline. It is the most straightforward choice if you want the S-Class nameplate without stretching too far on price.
• S 580: This trim adds the twin-turbo V8 and more power, making it the better fit if you want stronger performance without jumping to the AMG model. It suits you if you want the classic big-luxury-sedan feel with extra muscle.
• S 580e: This is the best-value trim if you want the strongest blend of efficiency and performance. It pairs the six-cylinder with electric assistance, delivers 48 miles of electric range, and is described as more efficient than the base six-cylinder while offering more power than the V8.
• AMG S 63 E Performance: This is the performance flagship, with a plug-in hybrid V8 setup and very serious output. It is the right pick if you want the most extreme acceleration and do not mind paying for it.

The Pinnacle trim adds rear-seat amenities and rear-seat side and seatbelt airbags.

Is now a good time to buy a used 2025 Mercedes-Benz S-Class?

This is a moderate market for selective buyers, so you can shop carefully and still find opportunities.

• Deal availability: 27.0% of listings are priced as good or great deals.
• Inventory: There are 477 listings available.
• Price trend: Prices have softened 11.21% compared with last year.
• Clean inventory: 95.8% of listings are accident-free.

If you find a listing below $126,982.95, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2025 Mercedes-Benz S-Class's resale value?

The current average of $126,822 sits slightly below last year's $142,835.

That price movement suggests the market has cooled, which can help you buy more selectively now. For a future seller, it also means you should pay close attention to trim, condition, and equipment, because well-kept examples are more likely to stand out when the market is softer.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2025 Mercedes-Benz S-Class safe?

It earns a 7/10 safety score from our experts.

Standard advanced safety features include forward collision warning with automatic emergency braking, adaptive cruise control, blind-spot monitoring with rear cross-traffic alert, lane-keep assist, automated lane-change assist, evasive steering assistance, automatic reverse braking, a semi-automated parking system, and a surround-view camera system. The Pinnacle trim augments that list with rear-seat side and seatbelt airbags.

The adaptive cruise control is described as excellent, with smooth transitions between acceleration and braking. The systems also functioned flawlessly in testing, without false alarms or odd glitches.

There are no published crash test results from NHTSA or IIHS for this generation, so you should lean more heavily on the standard safety equipment and the trim you choose.

Should I buy a 2025 Mercedes-Benz S-Class or consider a different year?

If you're weighing the 2025 against nearby model years, here's how to think about it:

Choose the 2025 if:

• 27.0% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 95.8% — clean inventory, standard diligence applies.
• Price trend: Prices have softened 11.21% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• Mercedes added newly standard digital key functionality and a center airbag this year.

The bottom line: If you want the freshest version of this flagship with the latest standard equipment and a softer market, the 2025 is the one to target. If your priority is simply finding the lowest possible price, a nearby model year may be worth comparing, but the 2025 already gives you a strong mix of inventory, satisfaction, and value movement.

These recommendations are based on CarGurus' proprietary market data from August 28, 2026, CarGurus experts' opinions, and generative AI.