CarGurus Logo Homepage Link
  • Buy
    • Used cars
    • New cars
    • Certified pre-owned
    • Start your purchase online
    • Dealerships near me
  • Sell
    • Sell my car
    • Car values
    • Sell my car FAQs
  • Finance
    • Prequalify for financing
    • How does it work?
    • Financing FAQs
  • Research
    • Test drive reviews
    • Price trends
    • Tips & advice
    • Electric cars
    • Compare cars
  • Discover
    The latest way to shop:
    smarter research, better
    listings.
  • Saved cars & searches
  • Sign in / Register
    • My account
    • Saved searches
    • Saved cars
    • Recommended cars
    • Browsing history
    • Financing dashboard
      • United States (EN)
      • Estados Unidos (ES)
      • Canada (EN)
      • Canada (FR)
      • United Kingdom

New & Used 2025 Lexus IS for Sale near Seneca, SC

88 results
Seneca, SC
2024 Lexus IS 350 F Sport AWD

2024 Lexus IS

350 F Sport AWD

18,237 miles

$45,990

Fair Deal
Duluth, GA
84 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Rioja Red
Transmission:
6-Speed Automatic
Mileage:
18,237
Stock number:
G4272P
VIN:
JTHGZ1E2XR5037088

Sponsored

2024 Lexus IS 350 F Sport RWD

2024 Lexus IS

350 F Sport RWD

15,230 miles

$40,998

Great Deal
Certified Pre-Owned
Greenville, SC
36 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Incognito
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
8-Speed Automatic
Mileage:
15,230
Stock number:
AR5079536
VIN:
JTHGZ1B26R5079536

Sponsored

2024 Lexus IS 350 F Sport RWD

2024 Lexus IS

350 F Sport RWD

25,625 miles

$39,990

Good Deal
Duluth, GA
83 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Rioja Red
Transmission:
8-Speed Automatic
Mileage:
25,625
Stock number:
R5076165
VIN:
JTHGZ1B24R5076165

Sponsored

2025 Lexus IS 500 F Sport Performance RWD

2025 Lexus IS

500 F Sport Performance RWD

11,571 miles

$68,798

Great Deal
Spartanburg, SC
61 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
472 hp 5L V8
Exterior color:
Flare Yellow
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
11,571
Stock number:
TS5006942
VIN:
JTHAP1D26S5006942

2024 Lexus IS 350 F Sport Design RWD

2024 Lexus IS

350 F Sport Design RWD

11,507 miles

$44,147

Fair Deal
Store transfer to Greenville, SC
150 mi away • Price includes $149 shipping Price includes $149 shipping
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
11,507
Stock number:
28228164
VIN:
JTHBZ1B29R5078682

2024 Lexus IS 300 RWD

2024 Lexus IS

300 RWD

16,295 miles

$38,997

Fair Deal
Store transfer to Greenville, SC
806 mi away • Price includes $999 shipping Price includes $999 shipping
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
White
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
16,295
Stock number:
28138367
VIN:
JTHCA1D29R5128778

Preparing for a close up...

Photos coming soon

2024 Lexus IS

350 F Sport RWD

15,230 miles

$40,998

Great Deal
Certified Pre-Owned
Greenville, SC
36 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Incognito
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
White
Transmission:
8-Speed Automatic
Mileage:
15,230
Stock number:
AR5079536
VIN:
JTHGZ1B26R5079536

Preparing for a close up...

Photos coming soon

2025 Lexus IS

350 F Sport RWD

3,248 miles

$45,890

Good Deal
Duluth, GA
84 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Gray / Black
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
3,248
Stock number:
G252505A
VIN:
JTHGZ1B28S5090737

Preparing for a close up...

Photos coming soon

2024 Lexus IS

300 AWD

9,617 miles

$42,420

Fair Deal
Buford, GA
73 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
260 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
6-Speed Automatic
Mileage:
9,617
Stock number:
R5053853
VIN:
JTHD81F29R5053853

Preparing for a close up...

Photos coming soon

2024 Lexus IS

300 RWD

22,638 miles

$35,999

Fair Deal
Snellville, GA
85 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
White
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
22,638
Stock number:
131997
VIN:
JTHCA1D23R5131997

Preparing for a close up...

Photos coming soon

2024 Lexus IS

350 F Sport AWD

18,237 miles

$45,990

Fair Deal
Duluth, GA
84 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Rioja Red
Transmission:
6-Speed Automatic
Mileage:
18,237
Stock number:
G4272P
VIN:
JTHGZ1E2XR5037088

Preparing for a close up...

Photos coming soon

2025 Lexus IS

500 F Sport Performance RWD

5,925 miles

$73,990

Fair Deal
Duluth, GA
84 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
472 hp 5L V8
Exterior color:
Ultra White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
5,925
Stock number:
G260431A
VIN:
JTHAP1D26S5008237

Preparing for a close up...

Photos coming soon

2024 Lexus IS

300 AWD

9,617 miles

$42,420

Fair Deal
Buford, GA
73 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
260 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown
Transmission:
6-Speed Automatic
Mileage:
9,617
Stock number:
R5053853
VIN:
JTHD81F29R5053853

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus IS
  4. / 2025
  5. / South Carolina
  6. / Seneca
FAQs

2025 Lexus IS FAQs

How much does the 2025 Lexus IS cost in Seneca, SC?

The average 2025 Lexus IS costs about $45,383.46. The average price has decreased by -5.2% since last year. The 44 for sale near Seneca, SC on CarGurus, range from $34,998 to $75,052 in price.

How many 2025 Lexus IS vehicles in Seneca, SC have no reported accidents or damage?

36 out of 44 for sale near Seneca, SC have no reported accidents or damage.

What is the fuel economy of the 2025 Lexus IS?

Depending on the engine and options, the 2025 Lexus IS gets between 20 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2026 Lexus IS in Seneca SC

  • 2024 Lexus IS

  • 2023 Lexus IS

  • 2022 Lexus IS

  • Lexus IS 300 RWD

  • Lexus IS 350 F Sport RWD

  • Lexus IS 300 AWD

  • Lexus IS 350 F Sport AWD

  • Lexus IS 350 F Sport Design RWD

  • Lexus IS 500 F Sport Performance Premium RWD

  • Lexus IS 350 F Sport 3 AWD in Seneca SC

  • Lexus IS 500 F Sport Performance RWD

  • Lexus IS 350 F Sport Design AWD

  • Lexus IS 300 F Sport Design RWD in Seneca SC

  • 2025 Lexus IS in Anderson SC

  • 2025 Lexus IS in Greenville SC

  • 2025 Lexus IS in Athens GA

  • 2025 Lexus IS in Gainesville GA

  • 2025 Lexus IS in Greenwood SC

  • 2025 Lexus IS in Spartanburg SC

  • 2025 Lexus IS in Asheville NC

  • 2025 Lexus IS in Lawrenceville GA

  • 2025 Lexus IS in Covington GA

  • Lexus IS in Seneca SC

  • Lexus SUVs & Crossovers for Sale in Seneca SC

  • Sports Cars for Sale in Seneca SC

  • Sports Cars Under $20,000 for Sale in Seneca SC

  • Reliable Cars For Sale in Seneca SC

  • Lexus Coupes for Sale Near Seneca SC

  • Affordable Luxury Cars For Sale in Seneca SC

  • Used Luxury Cars for Sale in Seneca SC

  • All Used Cars

  • Manual Transmission Cars

  • Luxury Cars

  • Cars with Red Interior

  • Cheap Manual Cars

  • Hybrid Cars

  • Sports Cars

  • Electric SUVs

  • Cheap Trucks

  • Small Cars

  • Third Row SUVs

  • Three Quarter Ton Trucks

  • Lifted Trucks

  • Manual Transmission Trucks

  • Diesel Trucks

  • Hybrid SUVs

  • Dually Trucks

  • One Ton Trucks

  • Cheap SUVs

  • Lifted Ford Trucks

  • 4x4 Trucks

  • Work Trucks

  • AWD SUVs

  • Ford Trucks

  • Chevrolet Trucks

  • Toyota Trucks

  • Trucks Under $10,000

  • Cars Under $15,000

  • Sports Cars Under $20,000

  • Trucks Under $20,000

  • Used Sedans for Sale with Low Mileage

  • Used SUVs / Crossovers for Sale with Low Mileage

  • Used Hatchbacks for Sale with Low Mileage

  • Used Convertibles for Sale with Low Mileage

  • Used Vans for Sale with Low Mileage

  • Used Minivans for Sale with Low Mileage

  • Used Pickup Trucks for Sale with Low Mileage

  • Used Coupes for Sale with Low Mileage

  • Used Wagons for Sale with Low Mileage

  • Lexus of Greenville

Connect with us
Download our app
Download on the App Store Get it on Google Play
  • Company
  • About CarGurus
  • Our team
  • Press
  • Investor relations
  • Price trends
  • Careers
  • Advertise with CarGurus
  • For dealers
  • Dealer signup
  • Dealer resources
  • Terms
  • Terms of use
  • Privacy policy
  • Interest-based ads
  • Security
  • Help
  • Help center
  • Contact us
Click for the BBB Business Review of this Auto Listing Service in Cambridge MA
    • United States (EN)
    • Estados Unidos (ES)
    • Canada (EN)
    • Canada (FR)
    • United Kingdom

© 2026 CarGurus, Inc., All Rights Reserved.