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New & Used 2025 Lexus IS for Sale near Defiance, MO

43 results
Defiance, MO
2024 Lexus IS 350 F Sport AWD

2024 Lexus IS

350 F Sport AWD

27,150 miles

$43,499

Fair Deal
O Fallon, MO
5 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Incognito
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
27,150
Stock number:
PK1628
VIN:
JTHGZ1E22R5033830

Sponsored

2024 Lexus IS 350 F Sport AWD

2024 Lexus IS

350 F Sport AWD

27,150 miles

$43,499

Fair Deal
O Fallon, MO
5 mi away
Year:
2024
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Incognito
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
27,150
Stock number:
PK1628
VIN:
JTHGZ1E22R5033830

Preparing for a close up...

Photos coming soon

2025 Lexus IS

350 F Sport 3 AWD

1,234 miles

$50,940

Fair Deal
Certified Pre-Owned
Manchester, MO
17 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Exterior color:
Incognito
Interior color:
White With Black
Transmission:
6-Speed Automatic
Mileage:
1,234
Stock number:
P1569
VIN:
JTHGZ1E20S5039745

Preparing for a close up...

Photos coming soon

2025 Lexus IS

New car | MSRP $69,829

$69,829

St. Louis, MO
20 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
472 hp 5L V8
Exterior color:
White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
5
Stock number:
P1F008738
VIN:
JTHAP1D26S5008738

Preparing for a close up...

Photos coming soon

2025 Lexus IS

New car | MSRP $51,559

$51,559

St. Louis, MO
20 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
5
Stock number:
LDD043340
VIN:
JTHBZ1E22S5043340

Preparing for a close up...

Photos coming soon

2025 Lexus IS

New car | MSRP $51,474

$51,474

St. Louis, MO
20 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
311 hp 3.5L V6
Exterior color:
Blue
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
5
Stock number:
PDF043201
VIN:
JTHBZ1E2XS5043201

Preparing for a close up...

Photos coming soon

2025 Lexus IS

New car | MSRP $54,294

$54,294

St. Louis, MO
20 mi away
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Interior color:
Black
Transmission:
Automatic
Mileage:
5
Stock number:
P1F043787
VIN:
JTHGZ1E23S5043787

Preparing for a close up...

Photos coming soon

2025 Lexus IS

300 RWD

6,676 miles

$43,447

No Price Analysis
Store transfer to Saint Peters, MO
537 mi away • Price includes $449 shipping Price includes $449 shipping
Year:
2025
Make:
Lexus
Model:
IS
Body type:
Sedan
Doors:
4 doors
Drivetrain:
Rear-Wheel Drive
Engine:
241 hp 2L I4
Exterior color:
Silver
Combined gas mileage:
26 MPG
Fuel type:
Gasoline
Interior color:
Red
Transmission:
Automatic
Mileage:
6,676
Stock number:
27972957
VIN:
JTHCA1D20S5133339

  1. Home
  2. / Used Cars
  3. / Lexus IS
  4. / 2025
  5. / Missouri
  6. / Defiance
FAQs

2025 Lexus IS FAQs

How much does the 2025 Lexus IS cost in Defiance, MO?

The average 2025 Lexus IS costs about $45,383.46. The average price has decreased by -5.2% since last year. The 35 for sale near Defiance, MO on CarGurus, range from $34,998 to $75,841 in price.

How many 2025 Lexus IS vehicles in Defiance, MO have no reported accidents or damage?

29 out of 35 for sale near Defiance, MO have no reported accidents or damage.

What is the fuel economy of the 2025 Lexus IS?

Depending on the engine and options, the 2025 Lexus IS gets between 20 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2026 Lexus IS in Defiance MO

  • 2024 Lexus IS

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  • Lexus IS 300 RWD

  • Lexus IS 350 F Sport RWD

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  • Lexus IS 350 F Sport AWD

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  • Lexus IS 350 F Sport 3 AWD in Defiance MO

  • Lexus IS 500 F Sport Performance RWD

  • Lexus IS 300 F Sport Design RWD

  • Lexus IS 350 F Sport Design AWD

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