Used 2022 Mercedes-Benz S-Class for Sale near London, KY
241 results
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 1,144 currently listed for sale and an average price of $65,830.00, 32.5% of 2022 Mercedes-Benz S-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.8% of 2022 S-Class models on CarGurus are accident-free.
The 2022 Mercedes-Benz S-Class features a cutting-edge 48-volt mild hybrid powertrain, luxurious interior finishes, and advanced technology systems that include a stunning OLED touchscreen and exceptional safety features.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
With 1,144 currently listed for sale and an average price of $65,830.00, 32.5% of 2022 Mercedes-Benz S-Class vehicles for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
88.8% of 2022 S-Class models on CarGurus are accident-free.
The 2022 Mercedes-Benz S-Class features a cutting-edge 48-volt mild hybrid powertrain, luxurious interior finishes, and advanced technology systems that include a stunning OLED touchscreen and exceptional safety features.
Why it stands out
The 2022 Mercedes-Benz S-Class continues to set the standard for luxury sedans with its elegant design and state-of-the-art technology. Offering a smooth ride thanks to its advanced powertrains—like the turbocharged 3.0-liter inline six-cylinder in the S500 and the twin-turbo 4.0-liter V8 in the S580—it provides both excellent performance and comfort. With impressive fuel economy ratings of up to 21 mpg city and 30 mpg highway for the S500, it strikingly balances power and efficiency.
Inside, the S-Class shines with high-end materials and impressive technology, such as the 12.8-inch OLED touchscreen and extensive driver-assistance features. Owner reviews capture the exceptional comfort and build quality that the S-Class is known for, while its ability to deliver a serene driving experience makes it a favorite for executives. Despite its premium price tag, the S-Class remains attractive thanks to its comprehensive luxury, cutting-edge tech offerings, and strong resale value.
Other model years to consider
- Average price: $80,994.00
- Good/great deal percentage: 32.4%
- User rating: Not available
- Total listings: 1,237
- Average price: $26,177.00
- Good/great deal percentage: 31.6%
- User rating: 4.95 / 5
- Total listings: 956
- Average price: $21,956.00
- Good/great deal percentage: 32.0%
- User rating: 5 / 5
- Total listings: 801
This analysis is based on CarGurus' proprietary market data from May 18, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
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Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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