Used 2022 Mercedes-Benz S-Class for Sale near Lexington, KY
251 results
CarGurus Analysis:
2022 Mercedes-Benz S-Class
With 1,152 currently listed for sale and an average price of $66,208.00, 30.4% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
89.1% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a 48-volt mild hybrid gasoline-electric powertrain, providing a luxurious and high-tech driving experience.
CarGurus Analysis: 2022 Mercedes-Benz S-Class
overall
Summary
With 1,152 currently listed for sale and an average price of $66,208.00, 30.4% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
89.1% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class features a 48-volt mild hybrid gasoline-electric powertrain, providing a luxurious and high-tech driving experience.
Why it stands out
The 2022 Mercedes-Benz S-Class sedan epitomizes modern executive transportation with its blend of luxury, performance, and cutting-edge technology. Its distinctive features include a choice between two powerful engines: the S500 with a turbocharged 3.0-liter inline-six and the S580 with a twin-turbo 4.0-liter V8, both complemented by a 48-volt mild hybrid system for enhanced efficiency and performance. The S-Class stands out for its sophisticated interior, characterized by high-quality materials and innovative design, including a striking 12.8-inch OLED touchscreen and a 12.3-inch digital instrument panel that offers customizable visual themes. This model brings a top-tier driving experience, with robust road handling and swift acceleration (the S500 reaches 0-60 mph in just 4.9 seconds). Enhanced safety features, including advanced driver assistance systems, further cement the S-Class’s status as a premier luxury sedan. While some may find its design polarizing, the overall excellence in luxury and technology ensures strong appeal among buyers seeking a prestigious vehicle.
Other model years to consider
- Average price: $81,427.00
- Good/great deal percentage: 30.6%
- User rating: Not available
- Total listings: 1,225
- Average price: $26,007.00
- Good/great deal percentage: 30.4%
- User rating: 4.95 / 5
- Total listings: 947
- Average price: $21,966.00
- Good/great deal percentage: 30.3%
- User rating: 5 / 5
- Total listings: 781
This analysis is based on CarGurus' proprietary market data from May 4, 2026, CarGurus experts' opinions, and generative AI.
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4.5 Overall rating
Filter by rating
Anonymous
Reviewed a 2022 Mercedes-Benz S-Class on Jun 7, 2024
The only option I wish it had was the premier stereo system. Otherwise the car was perfect. It was basically a new vehicle. The price I actually paid was great based on the immaculate condition and very low mileage.
Nabeel J
Reviewed a 2022 Mercedes-Benz S-Class on Apr 25, 2022
The S Class provides safety and comfort for its riders. At first, I decided to purchase the BMW 745e after comparing it with the Audi A8. I decided to give the Mercedes S class a try. After the test drive, I immediately decided to purchase the Mercedes S580. I do not regret my purchase at all. All of the looks of the car look fabulous. The ambient lighting is breathtaking as well as the display screen. The panoramic sunroof is also one of my favorites. I live in a hilly area, but I can’t even tell when going up the hill since the S580 is a powerful vehicle.
Sajid S
Reviewed a 2022 Mercedes-Benz S-Class on Dec 27, 2021
It’s been a pinnacle of luxury, however nothing stands out compared to previous models except some businesses including indoor lighting etc. the screen seems odd ;stands out in the middle and does not merge with the rest of the dashboard
Joyce E
Reviewed a 2022 Mercedes-Benz S-Class on Apr 18, 2024
This car has a manufacturer recall on its fuel pump mechanism, and it is a hybrid car, so for someone who leaves the car parked in the garage for 2 straight weeks, it may cause the battery to die and may not be suited for my needs/lifestyle
2022 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 580 4MATIC AWD | $117,700 |
| S 500 4MATIC AWD | $111,100 |
| Maybach S 680 4MATIC AWD | $229,000 |
| Maybach S 580 4MATIC AWD | $184,900 |
2022 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz S-Class prices has changed over time.
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