Used 2022 Mercedes-Benz S-Class for Sale near Hampton, TN

## Summary - With 1,084 currently listed for sale and an **average price of $65,944.00**, 30.9% of 2022 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Mercedes-Benz S-Class 4.8 / 5 stars. - **88.9% of 2022 S-Class models on CarGurus are accident free**. - The 2022 Mercedes-Benz S-Class features a luxurious interior, advanced technology such as a stunning OLED display, and an impressive hybrid powertrain, combining a turbocharged engine with mild-hybrid assistance for enhanced performance and efficiency. ## Why it stands out The 2022 Mercedes-Benz S-Class is a quintessential luxury sedan that embodies sophistication and advanced technology. It is powered by either a turbocharged 3.0-liter inline-six (S500) or a twin-turbo 4.0-liter V8 (S580), which are both paired with a nine-speed automatic transmission and the innovative 48-volt mild hybrid EQ Boost system. This combination achieves remarkable power with up to 429 hp and smooth, effortless acceleration, making it both a joy to drive and ride in. The vehicle's lavishly appointed interior features high-quality materials and cutting-edge tech, including a 12.8-inch touchscreen and a 12.3-inch digital instrument cluster, enhancing both utility and aesthetic appeal. While it competes with high-end rivals like the Audi A8 and BMW 7 Series, the S-Class remains well-regarded for its handling, comfort, and technological advancements. One of its notable strengths is its spacious cabin that offers immense luxury for both drivers and passengers, complemented by state-of-the-art safety features, making it an appealing choice for those seeking a blend of opulence and performance. ## Other model years to consider - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-c24430)** - Average price: $25,868.00 - Good/great deal percentage: 30.2% - User rating: 4.88 / 5 - Total listings: 971 - **[2014 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2014-Mercedes-Benz-S-Class-c24217)** - Average price: $21,915.00 - Good/great deal percentage: 30.4% - User rating: 4.89 / 5 - Total listings: 792 - **[2021 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2021-Mercedes-Benz-S-Class-c30896)** - Average price: $60,878.00 - Good/great deal percentage: 33.3% - User rating: 5 / 5 - Total listings: 798 This analysis is based on CarGurus' proprietary market data from March 23, 2026, CarGurus experts' opinions, and generative AI.