How much does the 2022 Mercedes-Benz GLS cost?

Prices have softened 13.87% compared to this time last year, making it a favorable time to shop this model year.

There are 903 listings available, which suggests you have room to compare options across the market.

If you find a listing below $48,562.71, that's toward the low end of the year-round range and worth acting on quickly.

Is the 2022 Mercedes-Benz GLS a good car?

Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating.

The standout strength is Look and feel at 9/10.

The GLS fits your needs if you want a large, upscale three-row SUV with a flagship feel and a spacious cabin. The overview also positions it as Mercedes’ SUV equivalent of the S-Class sedan, which matches the expert review’s emphasis on its luxury-first mission.

The trade-offs are worth weighing: the expert review calls out poor ride quality and poor ergonomic design, and notes that advanced safety features are not standard.

With 30.1% of listings marked as good or great deals, you have a decent chance of finding a strong-value example if you shop carefully.

Is the 2022 Mercedes-Benz GLS reliable?

Owners rate it 5/5, a strong signal of long-term satisfaction.

The overview presents the GLS as a high-end, capable three-row SUV, and the expert review reinforces that it delivers strong luxury credentials with a powerful engine and a spacious cabin. The 3.0-liter turbocharged inline-six with EQ Boost is described as smooth and strong enough for this big SUV, which supports confidence in everyday use.

Mercedes also includes a four-year, 50,000-mile basic warranty and a four-year, 50,000-mile powertrain warranty, which helps with early ownership peace of mind.

For used buyers, the main long-term risk is that a luxury SUV with this much equipment can become expensive if you inherit deferred maintenance or neglected wear items.

What should I look for when buying a used 2022 Mercedes-Benz GLS?

Accident-free inventory is solid at 87.2% — always verify the vehicle history report.

You should still check the history report carefully and prioritize a pre-purchase inspection, especially on a luxury SUV with available high-cost options. Focus on overall condition, signs of prior bodywork, and whether the vehicle’s equipment and maintenance history match the asking price.

Key things to evaluate:

• Trim level: The base GLS 450 has a more subtle look and a fairly basic interior by GLS standards, but it still feels properly luxurious with leather upholstery, a panoramic roof, ambient lighting, and a well-integrated digital cockpit. It does not include reclining rear seats, and some more dramatic or upscale features are reserved for other GLS versions.
• Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline-six with a nine-speed automatic and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an additional 21 hp and 184 lb-ft available in short bursts.
• Safety package: Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
• Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM, and natural-language voice recognition. A 13-speaker Burmester audio system is standard, while a head-up display is optional.
• Fuel efficiency: EPA fuel economy is 20 mpg combined, 18 mpg city, and 24 mpg highway.

Which 2022 Mercedes-Benz GLS trim should I buy?

The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.

Here's the short version:

The GLS 450 4Matic: is the only standard gas-model choice for this year, so your decision is less about trim shopping and more about whether the base configuration gives you enough luxury and capability. It brings the smooth inline-six, standard AWD, air suspension, and the core MBUX tech suite, which makes it the clear default pick for most used buyers.

Mercedes does leave some important safety features off the standard equipment list, so you should confirm whether the vehicle you’re considering has the driver-assistance options you want.

Is now a good time to buy a used 2022 Mercedes-Benz GLS?

This looks like a moderate, selective buyer’s market, so you can shop with some leverage but still need to move quickly on the right example.

• Deal availability: 30.1% of listings are priced as good or great deals.
• Inventory: There are 903 listings available.
• Price trend: Prices have softened 13.87% compared with last year.
• Clean inventory: 87.2% of listings are accident-free.

If you find a listing below $48,562.71, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Mercedes-Benz GLS's resale value?

The current average of $48,550 sits slightly below last year's $56,367.

That drop suggests the market has already adjusted downward, which can help you buy at a more favorable point in the cycle. If prices stabilize from here, a well-kept example could hold value better than one bought at a higher point in the market.

Strong condition matters a lot for resale in a luxury SUV like this, especially when buyers are comparing equipment, history, and overall presentation. A clean, well-optioned GLS should remain easier to move than one with visible wear or missing desirable features.

Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Mercedes-Benz GLS safe?

It earns a 6/10 safety score from our experts.

Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also includes a system that can warn if it’s unsafe to open a door when parked.

The key caveat is that Mercedes leaves several advanced safety features off the standard equipment list. You’ll have to pay extra for adaptive cruise control, lane-keep assist, second-row side airbags, and other more advanced driver-assistance features.

Should I buy a 2022 Mercedes-Benz GLS or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 30.1% of listings are priced as good or great deals.
• Accident-free inventory is solid at 87.2% — always verify the vehicle history report.
• Price trend: Prices have softened 13.87% compared with last year.
• Owners rate it 5/5 — a strong satisfaction signal.
• The 2022 stands out because Mercedes withdrew most V8 versions, leaving the GLS 450 as the only available model at the time.

Consider the 2021 if:

• At $47,685, the 2021 costs less than the current year's $48,550 average.
• It emphasizes luxury-first comfort and three-row practicality.

The bottom line: If you want the current-year GLS at a softened price and are comfortable with the base six-cylinder model, the 2022 is the cleaner buy. If your priority is saving a bit more upfront, the 2021 is the better price-sensitive alternative, especially if you find one in strong condition.

These recommendations are based on CarGurus' proprietary market data from August 28, 2026, CarGurus experts' opinions, and generative AI.