Used 2022 Mercedes-Benz GLS for Sale nearNew Orleans, LA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 51,029
- Stock #:
- 26G1969D
- VIN:
- 4JGFF5KE3NA787473


Sponsored by Legacy GMC of Slidell
2022 Mercedes-Benz GLS
450 4MATIC
51,029 mi
$44,988
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,430
- Stock #:
- 937342
- VIN:
- 4JGFF5KE1PA937342

Sponsored Listing
2023 Mercedes-Benz GLS
450 4MATIC
29,430 mi
$54,750
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 53,006
- Stock #:
- GS1458
- VIN:
- 4JGFF8GE8MA468644

2021 Mercedes-Benz GLS
580 4MATIC
53,006 mi
$48,910
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 84,274
- Stock #:
- 19165
- VIN:
- 4JGFF5KE0NA626210

2022 Mercedes-Benz GLS
450 4MATIC
84,274 mi
$37,903
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 20,567
- Stock #:
- 7585
- VIN:
- 4JGFF5KE9NA643779

2022 Mercedes-Benz GLS
450 4MATIC
20,567 mi
$49,719
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,489
- Stock #:
- VEL00410L
- VIN:
- 4JGFF5KE4NA588593

2022 Mercedes-Benz GLS
450 4MATIC
38,489 mi
$43,880
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 73,839
- Stock #:
- 1083
- VIN:
- 4JGFF5KE9MA439370

2021 Mercedes-Benz GLS
450 4MATIC
73,839 mi
$35,729
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,850
- Stock #:
- 004717
- VIN:
- 4JGFF8GE4PB004717

2023 Mercedes-Benz GLS
580 4MATIC
30,850 mi
$67,315
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 60,434
- Stock #:
- 1MT4940
- VIN:
- 4JGFF5KE7NA804940

2022 Mercedes-Benz GLS
450 4MATIC
60,434 mi
$42,491
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,346
- Stock #:
- 314813
- VIN:
- 4JGFF8KE4MA314813

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
30,346 mi
$76,910
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,375
- Stock #:
- P899415
- VIN:
- 4JGFF5KE8PA899415

-$3,000
2023 Mercedes-Benz GLS
450 4MATIC
55,375 mi
$46,776
$43,776
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 99,103
- Stock #:
- NV618337A
- VIN:
- 4JGFF5KE2MA464434

2021 Mercedes-Benz GLS
450 4MATIC
99,103 mi
$30,233
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- Automatic
- Mileage:
- 82,827
- Stock #:
- 423325
- VIN:
- 4JGFF5KE1MA423325

2021 Mercedes-Benz GLS
450 4MATIC
82,827 mi
$32,396
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 165 currently listed for sale and an average price of $44,988, 35.2% of 2022 Mercedes-Benz GLS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
92.1% of 2022 Mercedes-Benz GLS listings on CarGurus are accident free.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 51,029
- Stock #:
- 26G1969D
- VIN:
- 4JGFF5KE3NA787473

2022 Mercedes-Benz GLS
450 4MATIC
51,029 mi
$44,988
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 102,912
- Stock #:
- 323052
- VIN:
- 4JGFF5KE7MA323052

2021 Mercedes-Benz GLS
450 4MATIC
102,912 mi
$29,463
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,430
- Stock #:
- 937342
- VIN:
- 4JGFF5KE1PA937342

2023 Mercedes-Benz GLS
450 4MATIC
29,430 mi
$54,750
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 84,736
- Stock #:
- 19172
- VIN:
- 4JGFF5KE0MA428063

2021 Mercedes-Benz GLS
450 4MATIC
84,736 mi
$32,203
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Gray
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (IVORY)
- Transmission:
- Automatic
- Mileage:
- 74,346
- Stock #:
- 10040
- VIN:
- 4JGFF8GE6NA765414

-$2,391
2022 Mercedes-Benz GLS
580 4MATIC
74,346 mi
$47,129
$44,738
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 54,920
- Stock #:
- X902667
- VIN:
- 4JGFF5KE8PA902667

2023 Mercedes-Benz GLS
450 4MATIC
54,920 mi
$50,197
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,385
- Stock #:
- 1MT5035
- VIN:
- 4JGFF5KE3PA915035

2023 Mercedes-Benz GLS
450 4MATIC
50,385 mi
$52,891
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 66,790
- Stock #:
- 61515800
- VIN:
- 4JGFF5KE2NA615158

2022 Mercedes-Benz GLS
450 4MATIC
66,790 mi
$40,208
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,026
- Stock #:
- TB677090A
- VIN:
- 4JGFF5KE0NA741390

-$4,481
2022 Mercedes-Benz GLS
450 4MATIC
23,026 mi
$54,657
$50,176
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,880
- Stock #:
- 7497
- VIN:
- 4JGFF8KEXPA966128

2023 Mercedes-Benz GLS
AMG GLS 63 4MATIC
42,880 mi
$78,728
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 165 currently listed for sale and an average price of $44,988, 35.2% of 2022 Mercedes-Benz GLS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
92.1% of 2022 Mercedes-Benz GLS listings on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz GLS sits at the top of Mercedes’ luxury SUV range and is the brand’s biggest SUV. As the SUV equivalent of the S-Class sedan, it is positioned as Mercedes’ flagship utility vehicle, and that role comes through in its emphasis on size, luxury, and practicality. It is also a three-row SUV, which helps make it appealing to buyers who want a full-size luxury model with real passenger and cargo utility.
For 2022, Mercedes withdrew most of its V8 models from the United States, leaving only the base six-cylinder GLS 450 4Matic model. That makes this model year notable for being simpler than the broader GLS lineup, while still offering the upscale presence and spaciousness expected from the nameplate. The available test-drive feedback points to stylish design, a powerful engine, and a roomy cabin as key strengths.
There are tradeoffs, though. The same test-drive data calls out poor ride quality, notes that advanced safety features are not standard, and flags poor ergonomic design. Even so, the 2022 Mercedes-Benz GLS remains distinctive as a large, luxurious, three-row SUV that combines flagship status with everyday usefulness.
Other model years to consider
- 2024 Mercedes-Benz GLS
- Average price: $64,587
- Good/great deal percentage: 37.6%
- User rating: 5 / 5
- Total listings: 189
- 2025 Mercedes-Benz GLS
- Average price: $75,264
- Good/great deal percentage: 36.5%
- Total listings: 200
- 2023 Mercedes-Benz GLS
- Average price: $54,750
- Good/great deal percentage: 39.3%
- Total listings: 168
Similar models to consider
- 2022 BMW X7
- Average price: $29,990
- Good/great deal percentage: 33.7%
- User rating: 5 / 5
- Total listings: 190
- 2022 Audi Q7
- Average price: $28,878
- Good/great deal percentage: 59.0%
- User rating: 5 / 5
- Total listings: 195
- 2022 Lincoln Navigator
- Average price: $43,472
- Good/great deal percentage: 36.0%
- User rating: 5 / 5
- Total listings: 111
This analysis is based on CarGurus' proprietary market data from October 19, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends2022 Mercedes-Benz GLS Pricing Analysis: New Orleans, LA Market Report
Pricing in Nearby Cities
Market Area: New Orleans, LA
Key Insights
- Highest-Price Market: The Hammond, LA market leads with an average price of $39,999, indicating strong demand or limited supply.
- Best Value: The Mobile, AL market offers the lowest average price at $30,500, presenting a more affordable option for shoppers.
- Inventory Drives Stability: With 160 total listings, Hammond, LA has the most inventory, which may contribute to price stability in that area.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Hammond, LA | 160 | $39,999 |
| Mobile, AL | 158 | $30,500 |
| Baton Rouge, LA | 154 | $39,999 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 450 4MATIC trim has the highest inventory with 339 listings, indicating its popularity among buyers.
- Premium Spread: The AMG GLS 63 4MATIC trim commands a significant MSRP of $135,400, reflecting its luxury positioning in the market.
- Drivetrain Effect: All trims feature AWD, which may enhance their appeal in regions with varying weather conditions.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 339 | $77,850 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 49 | $101,250 | AWD | 4.0L 483 hp V8 |
| AMG GLS 63 4MATIC | 61 | $135,400 | AWD | 4.0L 603 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 56 | $165,100 | AWD | 4.0L 550 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year has a starting MSRP of $90,250, with an average price of $82,425, indicating a slight depreciation of 8.7%.
- Depreciation Curve: The 2017 model year shows the steepest depreciation at -77.6%, highlighting significant value loss over time.
- Best Value Sweet Spot: The 2023 model year averages $54,750, which is a substantial 33.1% below its starting MSRP of $81,800, making it a compelling option for budget-conscious buyers.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $90,250 | $82,425 | -8.7% |
| 2025 | $89,200 | $72,431 | -18.8% |
| 2024 | $87,000 | $67,439 | -22.5% |
| 2023 | $81,800 | $54,750 | -33.1% |
| 2018 | $69,550 | $19,995 | -71.3% |
| 2017 | $67,050 | $14,995 | -77.6% |
These recommendations are based on CarGurus' proprietary market data from October 14, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $46,133 |
| Year-Round Low | $46,133 |
| Year-Round High | $54,623 |
| Average Price a Year Ago | $54,631 |
| Change vs. Last Year | −15.55% |
Prices have softened 15.55% compared to this time last year, making it a favorable time to shop this model year.
There are 924 listings available, which suggests you should have some room to compare options.
Is the 2022 Mercedes-Benz GLS a good car?
Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating.
The standout strength is Look and feel at 9/10.
The GLS fits your needs if you want a flagship three-row luxury SUV with real passenger and cargo utility, plus a stylish, upscale cabin. The trade-offs are poor ride quality and poor ergonomic design, and advanced safety features are not standard.
With 39.6% of listings marked as good or great deals, you have a decent chance of finding a competitive price.
Is the 2022 Mercedes-Benz GLS reliable?
Owners rate it 5/5, a strong signal of long-term satisfaction.
The GLS is presented as a solid luxury SUV with a strong powertrain and a roomy, practical cabin. Its inline-six setup and mild-hybrid assist are described as smooth and well blended, which supports everyday drivability. Mercedes also backs it with a four-year, 50,000-mile basic warranty and a four-year, 50,000-mile powertrain warranty.
The first scheduled maintenance visit is on the house.
For used buyers, the main long-term risk is that a large, complex luxury SUV can become expensive if prior maintenance was skipped or if optional equipment needs attention.
What should I look for when buying a used 2022 Mercedes-Benz GLS?
Accident-free inventory is solid at 87.7% — always verify the vehicle history report.
You should still run a history report and prioritize a pre-purchase inspection, especially on a large luxury SUV with lots of standard and optional equipment. Focus on overall condition, signs of suspension wear, and whether the cabin electronics and driver aids work as expected. If you’re comparing listings, pay close attention to how well the vehicle has been maintained and whether it shows signs of heavy use.
Key things to evaluate:
- Trim level: In base GLS 450 form, the SUV has a more subtle, less flashy look, and the test car had a fairly basic interior by GLS standards. It still felt luxurious, but it did not have reclining seats.
- Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline six-cylinder engine with a nine-speed automatic transmission and EQ Boost mild-hybrid assistance. The engine makes 362 horsepower and 369 pound-feet of torque, with an electric motor that can add 21 hp and 184 lb-ft in short bursts.
- Safety package: Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
- Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto connectivity, navigation, SiriusXM satellite radio, and natural-language voice recognition.
- Fuel efficiency: EPA fuel-economy ratings for the GLS 450 4Matic are 20 mpg combined, 18 mpg city, and 24 mpg highway.
Which 2022 Mercedes-Benz GLS trim should I buy?
The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.
Here's the short version:
The GLS 450 4Matic is the one to buy because it is the only standard gas-model trim in this model year, and it already gives you the core GLS experience: a smooth inline-six powertrain, standard AWD, air suspension, and a roomy three-row layout. It suits you best if you want the flagship-size Mercedes SUV without waiting for higher-output versions to return.
Mercedes leaves some key safety features off the standard equipment list, so you should budget for the driver-assistance options if they matter to you.
Is now a good time to buy a used 2022 Mercedes-Benz GLS?
This looks like a moderate, selective buyer's market, so you can shop patiently but still move quickly on the right listing.
- Deal availability: 39.6% of listings are priced as good or great deals.
- Inventory: There are 924 listings available.
- Price trend: Prices have softened 15.55% compared with last year.
- Clean inventory: 87.7% of listings are accident-free.
If you find a listing below $46,133, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Mercedes-Benz GLS's resale value?
The current average of $46,133 sits slightly below last year's $54,631.
That price drop suggests the market has already adjusted downward, which can help you buy at a more favorable entry point. For a future seller, it also means you should expect resale value to depend heavily on condition, mileage, and equipment. Well-kept examples with clean history and desirable options should be easier to move than neglected ones.
Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Mercedes-Benz GLS safe?
It earns a 6/10 safety score from our experts.
Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also leaves several advanced features off the standard list, including adaptive cruise control, lane-keep assist, second-row side airbags, and other more advanced driver-assistance systems.
Should I buy a 2022 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 39.6% of listings are priced as good or great deals.
- Accident-free inventory is solid at 87.7% — always verify the vehicle history report.
- Price trend: Prices have softened 15.55% compared with last year.
- Owners rate it 5/5 — a strong satisfaction signal.
- The 2022 stands out for its simplified lineup, with only the base six-cylinder GLS 450 4Matic available.
Consider the 2021 if:
- At $46,614, the 2021 costs more than the current year's $46,133 average.
- It offers multiple powertrain options and impressive technology.
The bottom line: The 2022 is the better primary pick if you want the current-year GLS at a lower average price and with a simpler buying decision. If you’re price-sensitive and find a well-kept 2021 with the right equipment, that year can still make sense, but you’ll want to compare condition and features carefully before paying more.
These recommendations are based on CarGurus' proprietary market data from October 20, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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