Used 2022 Mercedes-Benz E-Class for Sale near Pittsburgh, PA
128 results
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 129 currently listed for sale near Pittsburgh, PA and an average price of $54,900.00, 31.0% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
83.7% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a variety of body styles, advanced driver-assistance technologies, and luxurious interior materials, epitomizing sophistication in the luxury vehicle sector.
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall

Summary
With 129 currently listed for sale near Pittsburgh, PA and an average price of $54,900.00, 31.0% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
83.7% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a variety of body styles, advanced driver-assistance technologies, and luxurious interior materials, epitomizing sophistication in the luxury vehicle sector.
Why it stands out
The 2022 Mercedes-Benz E-Class excels in offering an exceptional blend of luxury, performance, and advanced technology. Notably, it features a diverse range of body styles including coupe, convertible, sedan, and station wagon, appealing to a wide array of buyers looking for personalization. The introduction of turbocharged four-cylinder and six-cylinder engines, coupled with an advanced EQ Boost mild-hybrid technology, ensures a blend of performance and efficiency. Despite the omission of the V8 variants from the lineup, the remaining engines provide robust power suitable for any driving occasion.
Moreover, the 2022 model boasts state-of-the-art safety features, such as automatic emergency braking and blind-spot monitoring, mixed with luxurious amenities like heated seats and a premium Burmester sound system. The E-Class is designed to offer a serene driving experience, and its high-quality interior materials further elevate its status as a luxury vehicle. With an expert rating of 8.17 out of 10, it’s clear that the E-Class continues to impress in terms of performance, technology, and safety, despite some limitations in cost-effectiveness for value-conscious buyers.
Other model years to consider
- Average price: $25,250.00
- Good/great deal percentage: 29.0%
- User rating: 5 / 5
- Total listings: 183
- Average price: $29,762.00
- Good/great deal percentage: 30.6%
- User rating: 4.76 / 5
- Total listings: 258
- Average price: $19,339.00
- Good/great deal percentage: 30.8%
- User rating: 4.78 / 5
- Total listings: 221
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
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5.0 Overall rating
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Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 Cabriolet RWD | $73,250 |
| E 450 4MATIC Coupe AWD | $68,600 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 Coupe RWD | $66,100 |
| E 450 4MATIC Sedan AWD | $62,750 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
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