Used 2022 Mercedes-Benz E-Class for Sale near Denver, CO
115 results
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 112 currently listed for sale near Denver, CO and an average price of $41,011.00, 49.1% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
92.9% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class offers a luxurious driving experience with multiple body styles, advanced technology, and a powerful engine lineup, making it a standout choice in its class.
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall

Summary
With 112 currently listed for sale near Denver, CO and an average price of $41,011.00, 49.1% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
92.9% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class offers a luxurious driving experience with multiple body styles, advanced technology, and a powerful engine lineup, making it a standout choice in its class.
Why it stands out
The 2022 Mercedes-Benz E-Class showcases a unique blend of luxury and performance that sets it apart in the crowded sedan market. Available in coupe, convertible, sedan, and station wagon variants, the E-Class lineup caters to a wide range of buyer preferences. Despite a significant refresh in 2021, the 2022 model maintains its status as a leader in technology and comfort, highlighted by the award-winning MBUX infotainment system. The E-Class also benefits from a robust engine range — including turbocharged four-cylinder and six-cylinder options — ensuring that drivers experience both power and efficiency. Safety is a key focus, featuring an array of advanced driver assistance systems as standard, contributing to a highly secure driving environment. With its remarkable performance, luxurious interior, and multitude of customization options, the E-Class appeals to those seeking sophistication and driving pleasure.
Other model years to consider
- Average price: $45,686.00
- Good/great deal percentage: 49.4%
- User rating: 5 / 5
- Total listings: 83
- Average price: $45,792.00
- Good/great deal percentage: 31.3%
- User rating: 5 / 5
- Total listings: 134
- Average price: $28,370.00
- Good/great deal percentage: 25.3%
- User rating: 4.76 / 5
- Total listings: 178
This analysis is based on CarGurus' proprietary market data from April 21, 2026, CarGurus experts' opinions, and generative AI.
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 Cabriolet RWD | $73,250 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 4MATIC Coupe AWD | $68,600 |
| E 450 Coupe RWD | $66,100 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 450 4MATIC Sedan AWD | $62,750 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
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