Used 2022 Mercedes-Benz E-Class for Sale near Cleveland, OH
127 results
CarGurus Analysis:
2022 Mercedes-Benz E-Class
With 126 currently listed for sale near Cleveland, OH and an average price of $50,459.00, 45.2% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
100.0% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a diverse range of body styles, from coupe to convertible, and has introduced standard AMG-tuned models providing enhanced performance.
CarGurus Analysis: 2022 Mercedes-Benz E-Class
overall

Summary
With 126 currently listed for sale near Cleveland, OH and an average price of $50,459.00, 45.2% of 2022 Mercedes-Benz E-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz E-Class 5 / 5 stars.
100.0% of 2022 E-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz E-Class features a diverse range of body styles, from coupe to convertible, and has introduced standard AMG-tuned models providing enhanced performance.
Why it stands out
The 2022 Mercedes-Benz E-Class stands out in the luxury vehicle segment with its impressive selection of body styles, including coupe, convertible, sedan, and station wagon. Known for its refined interiors, the E-Class offers luxurious features such as comfortable seating, advanced safety systems, and high-tech infotainment options like the user-friendly MBUX system. The latest models focus on delivering a sporty driving experience with turbocharged four-cylinder and six-cylinder options, ensuring robust power and efficiency. Moreover, the E-Class Cabriolet provides a unique combination of high-end luxury with practicality, showcasing Mercedes’ commitment to comfort and performance. The offering of standard features, such as safety technologies and automated driving aids, makes it an attractive choice for discerning buyers.
Other model years to consider
- Average price: $48,392.00
- Good/great deal percentage: 47.2%
- User rating: 5 / 5
- Total listings: 89
- Average price: $43,065.00
- Good/great deal percentage: 29.4%
- User rating: 5 / 5
- Total listings: 160
- Average price: $17,871.00
- Good/great deal percentage: 24.2%
- User rating: 4.76 / 5
- Total listings: 240
This analysis is based on CarGurus' proprietary market data from April 21, 2026, CarGurus experts' opinions, and generative AI.
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2025 Mercedes-Benz E-Class Pricing, Specs, and Release Date
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5.0 Overall rating
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Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 6, 2025
The E-class is the midsize line of Mercedes cars, so it’s fine for all sizes except for very tall and large people. The new inline six cylinder is my favorite engine because it has plenty of power and is fuel efficient. Overall, the quality is here and has been for years.
Anonymous
Reviewed a 2022 Mercedes-Benz E-Class on Jul 12, 2024
Great value. 39K with 14K miles and in great condition with premium package. Took it to the Mercedes dealer for inspection and they said it was in great shape (tires, brakes, belts, filters, oil, fluid level, electronics, and even spark plugs). The interior was in pristine condition and the exterior is just as perfect.
Jim S
Reviewed a 2022 Mercedes-Benz E-Class on Mar 7, 2025
The E-class Mercedes Is the midsize car segment, and is large enough for many people who are not over 6’ 6” or more than 380 pounds in my estimation. Quality is noticed in interior seating and fit and finish. The relatively new Inline six cylinder engine has enough power with above average fuel economy. Other engines are available in four cylinder and eight cylinder variants.
Bill F
Reviewed a 2022 Mercedes-Benz E-Class on Jan 7, 2023
First class, quality material and build! You know maintenance is expensive going into it, but it is what it is.
2022 Mercedes-Benz E-Class Trims
| Trim type | MSRP |
|---|---|
| E 450 Cabriolet RWD | $73,250 |
| AMG E 53 Coupe 4MATIC | $77,600 |
| E 450 4MATIC Coupe AWD | $68,600 |
| E 450 Coupe RWD | $66,100 |
| AMG E 53 Sedan 4MATIC | $75,000 |
| E 450 4MATIC Sedan AWD | $62,750 |
| E 350 4MATIC | $57,450 |
| E 350 RWD | $54,950 |
2022 Mercedes-Benz E-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz E-Class prices has changed over time.
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