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Used 2022 Lexus RX for Sale near Opelika, AL

169 results
Opelika, AL
2022 Lexus RX 350 FWD Toyota of Newnan

2022 Lexus RX

350 FWD

92,295 miles

$30,499

Good Deal
Newnan, GA
63 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
92,295
Stock number:
P6832
VIN:
2T2HZMAA6NC247930

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

10,909 miles

$38,997

Good Deal
Dallas, GA
95 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Brown (Moonbeam Beige Metallic)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Glazed Caramel
Transmission:
8-Speed Automatic
Mileage:
10,909
Stock number:
DM5368
VIN:
2T2HZMAA4MC195244

Sponsored

2022 Lexus RX 350 FWD

2022 Lexus RX

350 FWD

40,467 miles

$34,987

Great Deal
Birmingham, AL
96 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
40,467
Stock number:
YNC230871
VIN:
2T2AZMAA6NC230871

Sponsored

2021 Lexus RX 350 FWD

2021 Lexus RX

350 FWD

91,145 miles

$28,894

Good Deal
Montgomery, AL
52 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
White Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
91,145
Stock number:
U200282
VIN:
2T2HZMAA6MC200282

2022 Lexus RX 350L FWD

2022 Lexus RX

350L FWD

26,779 miles

$42,997

Good Deal
Store transfer to Columbus, GA
1,910 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
CREAM
Transmission:
Automatic
Mileage:
26,779
Stock number:
28146572
VIN:
JTJHZKEA8N2029048

2021 Lexus RX 350L Luxury AWD

2021 Lexus RX

350L Luxury AWD

67,545 miles

$32,970

Great Deal
Carrollton, GA
73 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
White
Combined gas mileage:
21 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
67,545
Stock number:
M2032452
VIN:
JTJJZKFAXM2032452

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

38,124 miles

$41,998

Fair Deal
Irondale, AL
96 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
38,124
Stock number:
U238489
VIN:
2T2HZMAA7NC238489

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

46,972 miles

$35,455

Great Deal
Birmingham, AL
97 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
46,972
Stock number:
P9943
VIN:
2T2AZMAA4NC227984

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

52,479 miles

$36,997

Good Deal
Store transfer to Columbus, GA
1,897 mi away • Price includes $1,999 shipping Price includes $1,999 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Gray
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic Overdrive
Mileage:
52,479
Stock number:
28142708
VIN:
2T2AZMAA5NC233566

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

45,267 miles

$36,500

Fair Deal
Montgomery, AL
52 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Nebula Gray Pearl
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
45,267
Stock number:
VW9106A
VIN:
2T2HZMAA3MC191072

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350L FWD

32,184 miles

$39,999

Good Deal
Macon, GA
99 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
290 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
32,184
Stock number:
S031073A
VIN:
JTJHZKEA4N2023747

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 F Sport AWD

49,846 miles

$38,097

Great Deal
Store transfer to Columbus, GA
263 mi away • Price includes $99 shipping Price includes $99 shipping
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
49,846
Stock number:
28198194
VIN:
2T2SZMDA8MC263028

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

40,467 miles

$34,987

Great Deal
Birmingham, AL
96 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Brown (Tan)
Transmission:
Automatic
Mileage:
40,467
Stock number:
YNC230871
VIN:
2T2AZMAA6NC230871

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

88,257 miles

$34,419

Great Deal
Heflin, AL
69 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
88,257
Stock number:
133773A
VIN:
2T2YZMDA9NC334393

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Premium FWD

18,008 miles

$45,947

Good Deal
Columbus, GA
25 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
18,008
Stock number:
TGD21078
VIN:
JTJCHMAA0P2000953

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 F Sport Handling AWD

47,866 miles

$43,995

Fair Deal
Tallassee, AL
32 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Transmission:
8-Speed Automatic
Mileage:
47,866
Stock number:
4T20619
VIN:
2T2YZMDA7NC352441

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  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Alabama
  6. / Opelika
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Opelika, AL?

The average 2022 Lexus RX costs about $39,936.21. The average price has decreased by -4.9% since last year. The 136 for sale near Opelika, AL on CarGurus, range from $26,616 to $55,900 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Opelika, AL have no reported accidents or damage?

130 out of 136 for sale near Opelika, AL have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Opelika AL

  • 2024 Lexus RX

  • 2023 Lexus RX

  • 2021 Lexus RX

  • 2020 Lexus RX

  • 2019 Lexus RX

  • Lexus RX 350 FWD

  • Lexus RX 350 AWD

  • Lexus RX 350 F Sport AWD

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L FWD

  • Lexus RX 350L AWD

  • Lexus RX 350 F Sport FWD

  • Lexus RX 350L Luxury AWD

  • Lexus RX 350L Luxury FWD

  • Lexus RX 350 F Sport Series 3 AWD in Opelika AL

  • 2022 Lexus RX in Lagrange GA

  • 2022 Lexus RX in Anniston AL

  • 2022 Lexus RX in Atlanta GA

  • 2022 Lexus RX in Dothan AL

  • Lexus RX in Opelika AL

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