Used 2022 Lexus RX for Sale nearKnoxville, TN

How much does the 2022 Lexus RX cost?

Prices have softened 4.49% compared to this time last year, making it a favorable time to shop this model year.

There are 2,145 listings available, which gives you a solid pool of inventory to compare.

Is the 2022 Lexus RX a good car?

Yes — the 2022 Lexus RX earns a 4.77/5 user rating and a 7.33/10 expert rating. The model scores 8/10 across Cost effectiveness and Safety.

Owners consistently praise its comfortable cabin, smooth ride, and luxury feel, and they also call out its loaded feature set and advanced tech. The RX is framed as a strong fit if you want a relaxed, upscale driving experience rather than a sporty one.

The main trade-offs are its lack of pickup power and its polarizing design, and the ergonomics are not especially strong. In market terms, 36.7% of listings are priced as good or great deals, so you still have room to shop selectively.

Is the 2022 Lexus RX reliable?

Owners rate it 4.77/5, a strong signal of long-term satisfaction.

The owner feedback points to a vehicle that feels comfortable, dependable, and trouble-free over time, with a reputation for long-term confidence. The expert assessment also reinforces that theme by describing Lexus’ tradition of reliability as part of the RX’s appeal.

The RX’s comfort-focused setup and established mechanical formula should help reduce ownership surprises, though used buyers should still pay close attention to maintenance records and overall condition.

What should I look for when buying a used 2022 Lexus RX?

Accident-free inventory is solid at 82.4% — always verify the vehicle history report.

You should still run a history report on any RX you’re considering, even if the listing looks clean at first glance. Prioritize a pre-purchase inspection that checks the suspension, brakes, electronics, and interior wear, since comfort and tech are central to this model’s appeal. Focus on condition details that affect daily livability, including seat wear, infotainment operation, and evidence of uneven maintenance.

Key things to evaluate:

• Trim level: The gas model is offered in base 350, F Sport, and L trim levels. The base and L trims emphasize comfort and luxury appeal, while the F Sport adds a more athletic look with 20-inch wheels, black-housing mirrors, dark window trim, F Sport badging, and a unique front fascia. The base and L trims use 18-inch wheels, so you’ll want to check whether the equipment gap matters to you before paying more for the sportier appearance.
• Powertrain: The RX 350 uses a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic. Front-wheel drive is standard, with all-wheel drive available. If you want more efficiency, the hybrid RX 450h adds two electric motors and returns stronger fuel economy, but that is a separate model.
• Safety package: Lexus Safety System 2.0+ is standard, and it includes adaptive cruise control with stop-and-go, lane-departure warning with steering assist, road-sign recognition, lane-keeping assist, lane-tracing assist, pre-collision braking with cyclist and pedestrian detection, and intelligent high beams. Blind-spot monitoring, rear cross-traffic alert, a head-up display, and Lexus Enform Safety Connect are also standard. The IIHS top-tier “plus” designation depends on optional triple-beam LED headlights.
• Infotainment: Standard infotainment uses an 8-inch touchscreen, with a 12.3-inch screen available. The system includes Android Auto and Apple CarPlay integration, wireless charging, Amazon Alexa compatibility, a WiFi hotspot, navigation with cloud-based updates, and premium audio options. The touchpad interface is a usability weak point, so test it yourself before you buy.
• Fuel efficiency: The RX 350 is rated at 20 mpg city, 27 mpg highway, and 23 combined, while AWD or the three-row L model lowers those figures by 1 mpg. The least efficient gas version is the 350L AWD at 18 mpg city, 25 mpg highway, and 23 combined.

Which 2022 Lexus RX trim should I buy?

The 2022 Lexus RX is offered in 3 trim levels: base 350, F Sport, and L.

Here's the short version:

• base 350: This is the trim to start with if you want the RX’s core strengths without paying for extra styling or seating changes. It gives you the standard luxury feel, the standard safety suite, and the most straightforward path into the model.
• F Sport: Choose this if you want the most aggressive appearance and a more athletic setup. It adds 20-inch wheels, unique exterior treatment, and performance-oriented hardware, but the content also makes clear that the RX still leans more toward comfort than true sportiness.
• L: Pick this if you want the three-row, 7-passenger layout. It’s the right choice when passenger flexibility matters more than the sportier look of the F Sport.

The safety package is standard across the lineup, but the IIHS top-tier result depends on the optional triple-beam LED headlights.

Is now a good time to buy a used 2022 Lexus RX?

This is a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.

• Deal availability: 36.7% of listings are priced as good or great deals.
• Inventory: There are 2,145 listings available.
• Price trend: Prices have softened 4.49% compared with last year.
• Clean inventory: 82.4% of listings are accident-free.

If you find a listing below $39,160, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2022 Lexus RX's resale value?

The current average of $39,160 sits slightly below last year's $41,001.

That softer pricing can help you as a buyer now, but it also suggests future sellers may need to stay realistic on asking price. If the market continues to favor shoppers, resale values may remain under pressure unless a vehicle is especially clean, well-equipped, and well maintained.

Vehicles with strong owner satisfaction ratings, like this model year's 4.77/5, tend to retain buyer demand, which supports resale value over time.

Is the 2022 Lexus RX safe?

The 2022 Lexus RX earns a Top Safety Pick rating from the Insurance Institute for Highway Safety, but only with the optional triple-beam LED headlights. It also earns four-star ratings overall from NHTSA, with five-star ratings in side crash tests and four-star ratings in frontal crash and rollover resistance.

It earns an 8/10 safety score from our experts.

Lexus Safety System 2.0+ is standard, and it brings adaptive cruise control with stop-and-go, lane-departure warning with steering assist, road-sign recognition, lane-keeping assist, lane-tracing assist, pre-collision braking with cyclist and pedestrian detection, and intelligent high beams. Blind-spot monitoring, rear cross-traffic alert, a head-up display, and Lexus Enform Safety Connect are also standard.

The main caveat is that the RX misses the IIHS top-tier “plus” designation unless you get the optional triple-beam LED headlights. That means you should pay close attention to headlight equipment when comparing used listings.

Should I buy a 2022 Lexus RX or consider a different year?

If you're weighing the 2022 against nearby model years, here's how to think about it:

Choose the 2022 if:

• 36.7% of listings are priced as good or great deals.
• Accident-free inventory is solid at 82.4% — always verify the vehicle history report.
• Price trend: Prices have softened 4.49% compared with last year.
• Owners rate it 4.77/5 — a strong satisfaction signal.
• It’s a carryover year with minimal changes, including new colors and a standalone fog lamps option.

Consider the 2021 if:

• At $35,429, the 2021 costs less than the current year's $39,160 average.
• It keeps the familiar comfort-and-reliability formula with a few tech upgrades.

Consider the 2023 if:

• At $45,904, the 2023 costs more than the current year's $39,160 average.
• It brings a redesigned, more modern package with stronger technology and a fresh feel.

The bottom line: If you want the best balance of price, inventory, and proven satisfaction, the 2022 is the sensible default. If you’re especially price-sensitive, the 2021 is the value play; if you want a newer redesign and can spend more, the 2023 is the upgrade path.

These recommendations are based on CarGurus' proprietary market data from September 22, 2026, CarGurus experts' opinions, and generative AI.