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Used 2022 Lexus RX for Sale near Knoxville, TN

144 results
Knoxville, TN
2023 Lexus RX 350 Premium+ FWD Rusty Wallace Nissan

2023 Lexus RX

350 Premium+ FWD

33,612 miles

$49,662

Fair Deal
Knoxville, TN
3 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Macadamia W/ Ash Bamboo Trim
Transmission:
8-Speed Automatic
Mileage:
33,612
Stock number:
D7947A
VIN:
2T2BAMBA4PC020217

Sponsored

2023 Lexus RX 350 Luxury AWD

2023 Lexus RX

350 Luxury AWD

79,030 miles

$42,899

Good Deal
Hendersonville, NC
95 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Peppercorn
Transmission:
Automatic
Mileage:
79,030
Stock number:
P12766
VIN:
2T2BAMCA3PC015296

Sponsored

2023 Lexus RX 350 Premium AWD

2023 Lexus RX

350 Premium AWD

63,941 miles

$42,304

Good Deal
Cookeville, TN
90 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
Automatic
Mileage:
63,941
Stock number:
5030870
VIN:
2T2BAMCA1PC013272

Sponsored

2023 Lexus RX 350 Premium AWD

2023 Lexus RX

350 Premium AWD

63,941 miles

$42,304

Good Deal
Cookeville, TN
90 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Eminent White Pearl
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
Automatic
Mileage:
63,941
Stock number:
5030870
VIN:
2T2BAMCA1PC013272

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Luxury AWD

79,030 miles

$42,899

Good Deal
Hendersonville, NC
95 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Peppercorn
Transmission:
Automatic
Mileage:
79,030
Stock number:
P12766
VIN:
2T2BAMCA3PC015296

Preparing for a close up...

Photos coming soon

2021 Lexus RX

350 FWD

41,177 miles

$36,588

Good Deal
Knoxville, TN
11 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Matador Red Mica
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
41,177
Stock number:
262221
VIN:
2T2HZMAA0MC207597

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2023 Lexus RX

350 FWD

58,476 miles

$37,397

Great Deal
Store transfer to Knoxville, TN
417 mi away • Price includes $399 shipping Price includes $399 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Silver
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
58,476
Stock number:
28026828
VIN:
2T2BAMBA6PC003032

Preparing for a close up...

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2023 Lexus RX

350 Luxury FWD

34,832 miles

$46,496

Good Deal
Chattanooga, TN
97 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
White
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
34,832
Stock number:
TPC020022
VIN:
2T2BAMBA0PC020022

Preparing for a close up...

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2021 Lexus RX

350 FWD

113,914 miles

$27,800

Fair Deal
Knoxville, TN
3 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black (Caviar)
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Birch
Transmission:
8-Speed Automatic
Mileage:
113,914
Stock number:
212437
VIN:
2T2HZMAA3MC212437

Preparing for a close up...

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2021 Lexus RX

350 F Sport Handling AWD

119,669 miles

$32,228

Good Deal
Certified Pre-Owned
Chattanooga, TN
95 mi away
Year:
2021
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Ultra White
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
119,669
Stock number:
28302LT
VIN:
2T2YZMDA8MC283029

Preparing for a close up...

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2022 Lexus RX

350 FWD

48,661 miles

$39,695

Fair Deal
Knoxville, TN
11 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
White (Parchment)
Transmission:
8-Speed Automatic
Mileage:
48,661
Stock number:
LP89451A
VIN:
2T2HZMAAXNC253293

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2022 Lexus RX

350 AWD

48,573 miles

$39,297

Great Deal
Store transfer to Knoxville, TN
471 mi away • Price includes $299 shipping Price includes $299 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
48,573
Stock number:
28038140
VIN:
2T2HZMDA6NC339390

Preparing for a close up...

Photos coming soon

2023 Lexus RX

350 Luxury FWD

16,100 miles

$49,497

Great Deal
Store transfer to Knoxville, TN
716 mi away • Price includes $499 shipping Price includes $499 shipping
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Blue
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Brown (TAN)
Transmission:
Automatic
Mileage:
16,100
Stock number:
28429265
VIN:
JTJCHMAA4P2010997

Preparing for a close up...

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2023 Lexus RX

350 Premium AWD

53,860 miles

$45,848

Good Deal
Certified Pre-Owned
Chattanooga, TN
95 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Red (Copper Crest)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Palomino W/Ash Bamboo
Transmission:
8-Speed Automatic
Mileage:
53,860
Stock number:
020682LT
VIN:
2T2BAMCA0PC020682

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 AWD

82,515 miles

$34,491

Fair Deal
Kingsport, TN
88 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
82,515
Stock number:
ANC322306
VIN:
2T2HZMDA5NC322306

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Tennessee
  6. / Knoxville
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX ## Summary - With 2,087 currently listed for sale on CarGurus and an **average price of $39,873**, 32.2% of 2022 Lexus RX models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2022 Lexus RX 4.58 / 5 stars. - **84.3% of 2022 RX models on CarGurus are accident free**. - The 2022 Lexus RX maintains its position as a best-seller in the luxury midsize crossover segment thanks to its attractive design, luxurious interior, driving comfort, and reliability. ## Why it stands out The 2022 Lexus RX distinguishes itself with a modern and sporty design that features aggressive character lines and angular cues reminiscent of a boomerang. Available in various trims, including sporty F Sport and three-row L versions, the RX caters to different needs while delivering a high-quality feel inside. This luxury crossover is not just about looks; it's equipped with numerous standard advanced safety features as part of the Lexus Safety System 2.0+, making it a comforting choice for families and safety-conscious drivers alike. Although some users have pointed out limitations in pick-up power and gas mileage, the overall driving experience remains smooth and quiet, ideal for long journeys. With an extensive list of technology features, the RX is appealing for tech-savvy buyers. ## Other model years to consider - **[2021 Lexus RX](https://www.cargurus.com/Cars/l-Used-2021-Lexus-RX-c30886)** - Average price: $35,677.00 - Good/great deal percentage: 33.1% - User rating: 4.73 / 5 - Total listings: 1,350 - **[2020 Lexus RX](https://www.cargurus.com/Cars/l-Used-2020-Lexus-RX-c29337)** - Average price: $33,042.00 - Good/great deal percentage: 34.8% - User rating: 4.77 / 5 - Total listings: 1,100 - **[2023 Lexus RX](https://www.cargurus.com/Cars/l-Used-2023-Lexus-RX-c32334)** - Average price: $46,881.00 - Good/great deal percentage: 32.6% - User rating: 4.62 / 5 - Total listings: 2,497 This analysis is based on CarGurus' proprietary market data from March 9, 2026, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Knoxville, TN?

The average 2022 Lexus RX costs about $39,884.60. The average price has decreased by -3.2% since last year. The 139 for sale near Knoxville, TN on CarGurus, range from $27,800 to $55,670 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Knoxville, TN have no reported accidents or damage?

139 out of 139 for sale near Knoxville, TN have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or EV battery range).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Knoxville TN

  • 2024 Lexus RX in Knoxville TN

  • 2023 Lexus RX

  • 2021 Lexus RX in Knoxville TN

  • 2020 Lexus RX

  • 2019 Lexus RX

  • Lexus RX 350 FWD

  • Lexus RX 350 AWD

  • Lexus RX 350 F Sport AWD in Knoxville TN

  • Lexus RX 350 F Sport Handling AWD

  • Lexus RX 350L AWD

  • Lexus RX 350L FWD

  • Lexus RX 350 F Sport FWD

  • Lexus RX 350L Luxury AWD

  • Lexus RX 350L Luxury FWD

  • Lexus RX 350 F Sport Series 3 AWD

  • 2022 Lexus RX in Asheville NC

  • 2022 Lexus RX in Cookeville TN

  • Lexus RX in Knoxville TN

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