Used 2021 RAM 2500 for Sale near Des Moines, IA

## Summary - With 3,738 currently listed for sale and an **average price of $41,377.00**, 33.4% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 RAM 2500 4.48 / 5 stars. - **78.6% of 2021 RAM 2500 models on CarGurus are accident free**. - The 2021 RAM 2500 is praised for its powerful performance and fuel efficiency, particularly with the available diesel engine, along with strong safety features that enhance its value for money. ## Why it stands out The 2021 RAM 2500 stands out in the heavy-duty truck segment due to its remarkable blend of power, safety, and technology. With its impressive towing capacity and a choice of robust engines, including a powerful turbodiesel option, it appeals to those who require serious performance for work or recreation. The spacious interior accommodates families comfortably, making it more than just a utility vehicle. Despite its strengths, some owners have noted the need for modern interior features, like larger screens and more cooling options, which could enhance the overall driving experience. The truck’s lineage showcases continual improvements, proving it both a capable workhorse and a comfortable traveling companion. ## Other model years to consider - **[2020 RAM 2500](https://www.cargurus.com/Cars/l-Used-2020-RAM-2500-c29790)** - Average price: $39,506.00 - Good/great deal percentage: 33.1% - User rating: 4.74 / 5 - Total listings: 2,584 - **[2022 RAM 2500](https://www.cargurus.com/Cars/l-Used-2022-RAM-2500-c31581)** - Average price: $43,435.00 - Good/great deal percentage: 32.9% - User rating: 4.68 / 5 - Total listings: 3,841 - **[2023 RAM 2500](https://www.cargurus.com/Cars/l-Used-2023-RAM-2500-c32547)** - Average price: $49,616.00 - Good/great deal percentage: 33.9% - User rating: 4.6 / 5 - Total listings: 7,397 This analysis is based on CarGurus' proprietary market data from March 23, 2026, CarGurus experts' opinions, and generative AI.