Used 2021 Mercedes-Benz S-Class for Sale near Boston, MA
163 results
CarGurus Analysis:
2021 Mercedes-Benz S-Class
With 163 currently listed for sale near Boston, MA and an average price of $59,912.00, 31.9% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.0% of 2021 S-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz S-Class features a redesigned infotainment system, state-of-the-art technology integration, and powerful engine options that enhance its luxury sedan status.
CarGurus Analysis: 2021 Mercedes-Benz S-Class
overall
Summary
With 163 currently listed for sale near Boston, MA and an average price of $59,912.00, 31.9% of 2021 Mercedes-Benz S-Classes for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars.
84.0% of 2021 S-Class models on CarGurus are accident-free.
The 2021 Mercedes-Benz S-Class features a redesigned infotainment system, state-of-the-art technology integration, and powerful engine options that enhance its luxury sedan status.
Why it stands out
The 2021 Mercedes-Benz S-Class remains a flagship model that exemplifies luxury and innovation. With significant updates over its predecessor, this model offers advanced technology, a choice of robust engines, including a newly designed 4.0-liter twin-turbo V8 and a mild-hybrid system that enhances both performance and efficiency. Noteworthy is its impressive acceleration, reaching 0 to 60 mph in as fast as 4.4 seconds. The S-Class also boasts luxurious interior features such as a sophisticated infotainment system with a 12.8-inch touchscreen and high-quality materials, asserting its status as a top-tier luxury vehicle. However, potential buyers should be aware of the high price point, which is indicative of the complexities involved in maintaining such a high-end car. Overall, the 2021 S-Class stands out for its balance of power, comfort, and cutting-edge technology, making it a compelling choice for those in the luxury sedan market.
Other model years to consider
- Average price: $65,879.00
- Good/great deal percentage: 26.3%
- User rating: 4.8 / 5
- Total listings: 224
- Average price: $25,638.00
- Good/great deal percentage: 26.3%
- User rating: 4.88 / 5
- Total listings: 198
- Average price: $42,668.00
- Good/great deal percentage: 31.7%
- User rating: 4.85 / 5
- Total listings: 142
This analysis is based on CarGurus' proprietary market data from April 7, 2026, CarGurus experts' opinions, and generative AI.
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Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Deno P
Reviewed a 2021 Mercedes-Benz S-Class on Mar 23, 2023
This car is the ultimate in form and function. It is engineered to exacting performance standards to operate in its pure intent as an automobile to get from point A to B. But it has state of the art exquisite technology and appointments that are so mind blowing that you would drive right past B headed to Z. Performance, comfort and luxury at is best is what this car is.
Rob G
Reviewed a 2021 Mercedes-Benz S-Class on Feb 25, 2022
Full of technology. Easy learning curve. Handles beautifully. Acceleration makes you giggle.
2021 Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| AMG S 63 Cabriolet 4MATIC | $185,400 |
| Maybach S 580 Sedan 4MATIC | $184,900 |
| S 560 Cabriolet RWD | $140,000 |
| AMG S 63 Coupe 4MATIC | $173,100 |
| S 500 Sedan 4MATIC | $109,800 |
| S 560 Coupe 4MATIC | $131,400 |
| S 580 Sedan 4MATIC | $116,300 |
2021 Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz S-Class prices has changed over time.
See more price trends
