Used 2021 Mercedes-Benz GLS for Sale nearHuntsville, TX
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Crystal White/Silver Gray Pearl
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,653
- Stock #:
- 260723A
- VIN:
- 4JGFF5KE2NA726907


Sponsored by Bayway Lincoln
2022 Mercedes-Benz GLS
450 4MATIC
49,653 mi
$46,515
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 71,959
- Stock #:
- IE06221
- VIN:
- 4JGFF5KE9NA781614

Sponsored Listing
2022 Mercedes-Benz GLS
450 4MATIC
71,959 mi
$40,128
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,335
- Stock #:
- VS488446A
- VIN:
- 4JGFF8KE8MA486052

Sponsored Listing
2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
46,335 mi
$69,225
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Crystal White/Silver Gray Pearl
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,653
- Stock #:
- 260723A
- VIN:
- 4JGFF5KE2NA726907

2022 Mercedes-Benz GLS
450 4MATIC
49,653 mi
$46,515
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 72,541
- Stock #:
- MA428151
- VIN:
- 4JGFF5KE8MA428151

2021 Mercedes-Benz GLS
450 4MATIC
72,541 mi
$34,220
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,335
- Stock #:
- VS488446A
- VIN:
- 4JGFF8KE8MA486052

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
46,335 mi
$69,225
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,606
- Stock #:
- LR629520A
- VIN:
- 4JGFF5KE3NA694372

2022 Mercedes-Benz GLS
450 4MATIC
49,606 mi
$45,738
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 116,168
- Stock #:
- 131104
- VIN:
- 4JGFF5KE6LA131104

2020 Mercedes-Benz GLS
450 4MATIC
116,168 mi
$24,220
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 103,537
- Stock #:
- 4670
- VIN:
- 4JGFF5KE5LA137931

2020 Mercedes-Benz GLS
450 4MATIC
103,537 mi
$29,142
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,140
- Stock #:
- 25837B
- VIN:
- 4JGFF5KE1NA762393

2022 Mercedes-Benz GLS
450 4MATIC
21,140 mi
$51,365
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- TAUPE
- Transmission:
- Automatic
- Mileage:
- 35,263
- Stock #:
- 70125816
- VIN:
- 4JGFF5KE4LA118612

2020 Mercedes-Benz GLS
450 4MATIC
35,263 mi
$40,997
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 50,036
- Stock #:
- TNA730389
- VIN:
- 4JGFF5KE4NA730389

2022 Mercedes-Benz GLS
450 4MATIC
50,036 mi
$45,217
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 86,212
- Stock #:
- TB516996A
- VIN:
- 4JGFF5KE6LA135573

2020 Mercedes-Benz GLS
450 4MATIC
86,212 mi
$30,994
CarGurus Analysis:
2021 Mercedes-Benz GLS
With 766 currently listed for sale and an average price of $47,830.00, 35.6% of 2021 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.67 / 5 stars and CarGurus experts gave it an 8.33 / 10.
84.7% of 2021 GLS models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 106,724
- Stock #:
- WG11829A
- VIN:
- 4JGFF5KE4MA576717

2021 Mercedes-Benz GLS
450 4MATIC
106,724 mi
$26,980
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,319
- Stock #:
- 305698LT
- VIN:
- 4JGFF8KE7MA305698

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
64,319 mi
$60,165
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown
- Transmission:
- Automatic
- Mileage:
- 95,644
- Stock #:
- 285184
- VIN:
- 4JGFF5KEXLA285184

2020 Mercedes-Benz GLS
450 4MATIC
95,644 mi
$28,186
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 103,778
- Stock #:
- T00321
- VIN:
- 4JGFF5KE4LA094912

2020 Mercedes-Benz GLS
450 4MATIC
103,778 mi
$29,601
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Red
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 62,614
- Stock #:
- 5101
- VIN:
- 4JGFF5KE9LA153002

2020 Mercedes-Benz GLS
450 4MATIC
62,614 mi
$33,102
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- CREAM
- Transmission:
- Automatic
- Mileage:
- 48,709
- Stock #:
- 70101284
- VIN:
- 4JGFF5KE7NA753245

2022 Mercedes-Benz GLS
450 4MATIC
48,709 mi
$47,897
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,780
- Stock #:
- TMA434190
- VIN:
- 4JGFF8KE2MA434190
Photos coming soon
2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
46,780 mi
$70,216
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 68,309
- Stock #:
- TMA458986
- VIN:
- 4JGFF5KE0MA458986

2021 Mercedes-Benz GLS
450 4MATIC
68,309 mi
$35,219
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Silver
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 95,334
- Stock #:
- WJ0523T
- VIN:
- 4JGFF5KE8LA270523

2020 Mercedes-Benz GLS
450 4MATIC
95,334 mi
$29,484
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Iridium Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black/Magma Grey
- Transmission:
- Automatic
- Mileage:
- 66,742
- Stock #:
- PC2552
- VIN:
- 4JGFF5KE9LA195430

2020 Mercedes-Benz GLS
450 4MATIC
66,742 mi
$33,357
CarGurus Analysis: 2021 Mercedes-Benz GLS
overall

Summary
With 766 currently listed for sale and an average price of $47,830.00, 35.6% of 2021 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.67 / 5 stars and CarGurus experts gave it an 8.33 / 10.
84.7% of 2021 GLS models on CarGurus are accident free.
Why it stands out
The 2021 Mercedes-Benz GLS is positioned as a luxury-first full-size SUV, and its appeal starts with the way it blends three-row practicality with a premium feel. Mercedes ties the “S” in its name to the S-Class flagship sedan, and the GLS is presented as the “S-Class of SUVs,” which captures its emphasis on comfort and refinement. It also offers spacious seating for three rows, along with enough cargo room for groceries, weekend bags, and even larger items that would be difficult to fit in a sedan.
What makes the 2021 GLS distinctive is that it does not stop at comfort alone. The available performance is described as surprising, and the SUV is credited with multiple powertrain options, plenty of cargo space, and impressive technology. At the same time, it is not without drawbacks: the third row is cramped, the technology can be unintuitive, and fuel economy is poor. That mix makes the GLS appealing to buyers who want a high-end, full-size SUV with strong luxury credentials, while still accepting some compromises in usability and efficiency.
Other model years to consider
- Average price: $72,856.00
- Good/great deal percentage: 34.1%
- User rating: 5 / 5
- Total listings: 1,389
- Average price: $33,202.00
- Good/great deal percentage: 35.8%
- User rating: 5 / 5
- Total listings: 754
- Average price: $79,306.00
- Good/great deal percentage: 33.9%
- Total listings: 1,446
This analysis is based on CarGurus' proprietary market data from August 31, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Wilber R
Reviewed a 2021 Mercedes-Benz GLS on Sep 4, 2024
Excellent car, very good finish full of attributes, spacious.
James C
Reviewed a 2021 Mercedes-Benz GLS on Dec 22, 2022
I feel that the features listed for this vehicle is good. I just didnt see one option that would have made me buy the vehicle fast. I did not see the multi contour massage feature. I wished that it would have been made clear on the listing.
Michelle A
Reviewed a 2021 Mercedes-Benz 450 4MATIC on Apr 8, 2023
Very nice ride, drives so well and well built. I love it so far!!
2021 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 450 4MATIC | $76,000 |
| AMG GLS 63 4MATIC AWD | $132,100 |
| 580 4MATIC | $98,850 |
| 600 Mercedes-Maybach 4MATIC | $160,500 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz GLS prices has changed over time.
See more price trends2021 Mercedes-Benz GLS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Miami: The city of Miami, FL has the highest average price at $83,852, indicating strong demand for luxury vehicles in this market.
- Lowest Prices in Philadelphia: Conversely, Philadelphia, PA offers the lowest average price at $39,093, suggesting a more price-sensitive market or higher inventory turnover.
- Inventory Variation: Cities like New York (215 listings) and Chicago (149 listings) have substantial inventory, which may contribute to more stable pricing compared to cities with lower listings.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Miami, FL | 125 | $83,852 |
| New York, NY | 215 | $54,347 |
| Chicago, IL | 149 | $55,882 |
| Dallas, TX | 119 | $48,472 |
| Philadelphia, PA | 171 | $39,093 |
| Houston, TX | 112 | $48,497 |
| Atlanta, GA | 164 | $49,643 |
| Boston, MA | 158 | $46,139 |
| Los Angeles, CA | 121 | $53,422 |
| Washington, DC | 174 | $38,532 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 450 4MATIC trim leads the inventory with 2,608 listings, indicating its popularity among buyers.
- Price Range Across Trims: The 600 Mercedes-Maybach 4MATIC is the most expensive trim with an MSRP of $160,500, reflecting its luxury positioning in the market.
- AWD Demand: All trims feature AWD, catering to consumer preferences for all-weather capability, which is likely driving demand.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 2608 | $76,000 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 339 | $98,850 | AWD | 4.0L 483 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 168 | $160,500 | AWD | 4.0L 550 hp V8 |
| AMG GLS 63 4MATIC AWD | 52 | $132,100 | AWD | 4.0L 603 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New Models at Premium Prices: The 2026 model is priced at $102,375, which is 13.5% above MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2019 model shows a steep decline, priced at $24,636, which is -64.8% vs MSRP, reflecting typical depreciation patterns for luxury vehicles.
- Best Value in Recent Models: The 2022 model is priced at $51,819, representing a -33.5% depreciation, making it a potentially attractive option for buyers seeking a balance of price and features.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Mercedes-Benz GLS | $90,250 | $102,375 | +13.5% |
| 2025 Mercedes-Benz GLS | $89,200 | $83,033 | -6.5% |
| 2024 Mercedes-Benz GLS | $87,000 | $77,422 | -11.0% |
| 2023 Mercedes-Benz GLS | $81,800 | $67,880 | -17.0% |
| 2022 Mercedes-Benz GLS | $77,850 | $51,819 | -33.5% |
| 2020 Mercedes-Benz GLS | $75,200 | $34,302 | -54.4% |
| 2019 Mercedes-Benz GLS | $70,150 | $24,636 | -64.8% |
| 2018 Mercedes-Benz GLS | $69,550 | $22,563 | -67.6% |
| 2017 Mercedes-Benz GLS | $67,050 | $19,167 | -71.4% |
These recommendations are based on CarGurus' proprietary market data from September 3, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $48,263 |
| Year-Round Low | $47,874.80 |
| Year-Round High | $53,241.18 |
| Average Price a Year Ago | $53,247 |
| Change vs. Last Year | −9.36% |
Prices have softened 9.36% compared to this time last year, making it a favorable time to shop this model year.
There are 801 listings available, which gives you a meaningful amount of inventory to compare.
If you find a listing below $47,874.80, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Mercedes-Benz GLS a good car?
Yes — the 4.67/5 user rating points to strong owner satisfaction, and the expert score is 8.33/10.
The model scores 9/10 across Look and feel, Performance, Technology, and Safety.
The 2021 GLS is positioned as a luxury-first full-size SUV, and its appeal starts with three-row practicality wrapped in a premium cabin. The overview also makes clear that you get spacious seating and useful cargo room, so you can use it as a family hauler without giving up the upscale feel.
The trade-offs are real: the third row is cramped, the technology can be unintuitive, and fuel economy is poor. Even so, the combination of multiple powertrain options, strong performance, and impressive technology makes it a compelling fit if you want a high-end three-row SUV and can live with some compromises.
35.6% of listings are priced as good or great deals, which suggests there are still worthwhile opportunities in the market.
Is the 2021 Mercedes-Benz GLS reliable?
Owners rate it 4.67/5, a strong signal of long-term satisfaction.
The overview points to a model built around comfort, refinement, and practical three-row utility, while the expert review reinforces that it delivers a composed, premium driving experience. The performance notes also show a sophisticated setup with multiple powertrain choices and EQ Boost support across the lineup, which adds to the sense of engineering depth.
The performance content also highlights EQ Boost’s ability to add extra power when needed and help spool the turbochargers more quickly. On the ownership side, that kind of system can make the vehicle feel more polished in daily use, though it also adds complexity compared with a simpler powertrain.
For used buyers, the main long-term risk is that a luxury SUV with this much technology and hardware can be costly to keep in top shape if prior maintenance was neglected.
What should I look for when buying a used 2021 Mercedes-Benz GLS?
Accident-free inventory is solid at 83.6% — always verify the vehicle history report.
You should still check the history report carefully, because a clean listing percentage does not replace a proper records review. Prioritize a pre-purchase inspection that focuses on the suspension, electronics, and interior condition, since this is a tech-heavy luxury SUV. Pay close attention to how the third row, infotainment controls, and driver-assistance features operate in real-world use.
Key things to evaluate:
- Trim level: The GLS 450 includes remote keyless entry, remote start, nine USB ports, dual-zone automatic climate control, heated front seats, a power liftgate, wireless device charging, Apple CarPlay, Android Auto, satellite radio, and a 13-speaker Burmester sound system. The GLS 580 adds V8 power plus heated-and-cooled front seats, massaging front seats, illuminated running boards, soft-close doors, and five-zone automatic climate control. The AMG GLS 63 adds more aggressive bodywork, a quad-outlet exhaust, and a performance-focused cabin treatment.
- Powertrain: The GLS 450 uses a twin-turbocharged 3.0-liter inline-six with 362 horsepower and 369 pound-feet of torque. The GLS 580 uses a twin-turbocharged 4.0-liter V8 with 483 hp and 516 lb-ft. The AMG GLS 63 uses a hand-crafted 4.0-liter twin-turbo V8 with 603 hp and 627 lb-ft. All engines include EQ Boost mild-hybrid support.
- Safety package: Standard equipment includes Active Brake Assist, forward-collision avoidance, rain-sensing wipers, blind-spot monitoring, automatic high beams, automatic parking assist, a surround-view camera system, a driver-drowsiness monitor, and crosswind assist. Available features include lane-keep assist, lane-change assist, adaptive cruise control, a following-distance indicator, and stop-and-go cruise control.
- Infotainment: The GLS uses the MBUX system with a massive touchscreen, a trackpad controller, Apple CarPlay, Android Auto, and voice control through “Mercedes” or “Hey Mercedes.” The digital dash and steering-wheel touch controls add capability, but they also create a learning curve.
- Fuel efficiency: The GLS 450 returns 20 mpg city, 24 highway, and 21 combined. The GLS 63 returns 14 mpg city, 18 highway, and 16 combined. In combined driving, the GLS 63 was observed at 15.3 mpg.
Which 2021 Mercedes-Benz GLS trim should I buy?
The 2021 Mercedes-Benz GLS is offered in 3 trim levels: GLS 450, GLS 580, and Mercedes-AMG GLS 63.
Here's the short version:
- GLS 450: This is the best-value choice if you want the core GLS experience with strong standard equipment, including heated front seats, wireless charging, Apple CarPlay, Android Auto, and a Burmester audio system. It gives you the luxury, space, and technology that define the model without pushing into the highest price tiers.
- GLS 580: Choose this if you want more power and a richer feature set, including V8 performance, massaging front seats, soft-close doors, and five-zone climate control. It makes sense if you want the GLS to feel more indulgent and you are willing to pay for it.
- Mercedes-AMG GLS 63: This is the performance-focused version, with the most powerful engine, more aggressive styling, and a cabin that leans into sportier character. It suits you if acceleration and presence matter more than value.
The GLS 450 includes the most approachable standard setup, while the GLS 580 and AMG GLS 63 add more luxury and performance. Safety equipment is generous across the lineup, with additional driver-assistance features available beyond the standard package.
Is now a good time to buy a used 2021 Mercedes-Benz GLS?
This looks like a moderate, selective buyer’s market, so you can shop with some leverage if you compare listings carefully.
- Deal availability: 35.6% of listings are priced as good or great deals.
- Inventory: There are 801 listings available.
- Price trend: Prices have softened 9.36% compared with last year.
- Clean inventory: 83.6% of listings are accident-free.
If you find a listing below $47,874.80, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Mercedes-Benz GLS's resale value?
The current average of $48,263 sits slightly below last year's $53,247.
That price movement suggests the market has cooled enough to give you better entry pricing now than a year ago. If you buy well today, you may reduce the risk of overpaying relative to recent market highs.
For a future seller, the softer pricing environment means resale gains may be harder to realize quickly. Still, a well-kept GLS with desirable equipment and strong condition should remain appealing to luxury-SUV shoppers.
Vehicles with strong owner satisfaction ratings, like this model year's 4.67/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Mercedes-Benz GLS safe?
It earns a 9/10 safety score from our experts.
The GLS comes standard with Active Brake Assist, forward-collision avoidance, rain-sensing wipers, blind-spot monitoring, automatic high beams, automatic parking assist, a surround-view camera system, a driver-drowsiness monitor, and crosswind assist. Available safety tech includes lane-keep assist, lane-change assist, adaptive cruise control, a following-distance indicator, and stop-and-go cruise control.
That standard equipment list is strong, but you should still check whether a specific used example has the optional driver-assistance features you want. The safety package is broad, yet some of the more advanced convenience features remain optional.
Should I buy a 2021 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 35.6% of listings are priced as good or great deals.
- Accident-free inventory is solid at 83.6% — always verify the vehicle history report.
- Price trend: Prices have softened 9.36% compared with last year.
- Owners rate it 4.67/5 — a strong satisfaction signal.
- The 2021 GLS stands out for its luxury-first three-row layout, strong performance options, and impressive technology.
Consider the 2022 if:
- At $48,156, the 2022 costs less than the current year's $48,263 average.
- Mercedes made the 2022 the brand’s flagship SUV with only the base six-cylinder GLS 450 4Matic available at the time.
The bottom line: If you want the broader trim range and the strongest mix of luxury, performance, and technology, the 2021 is the better target. If you are price-sensitive and comfortable with a narrower lineup, the 2022 can be the simpler buy.
These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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