Used 2021 Lexus RX for Sale near San Diego, CA
53 results
CarGurus Analysis:
2021 Lexus RX
With 58 currently listed for sale near San Diego, CA and an average price of $34,074.00, 91.4% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
100.0% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX maintains its reputation as a reliable luxury SUV, offering smooth driving, comfort, and new standard safety systems.
CarGurus Analysis: 2021 Lexus RX
overall

Summary
With 58 currently listed for sale near San Diego, CA and an average price of $34,074.00, 91.4% of 2021 Lexus RX models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars.
100.0% of 2021 RX models on CarGurus are accident free.
The 2021 Lexus RX maintains its reputation as a reliable luxury SUV, offering smooth driving, comfort, and new standard safety systems.
Why it stands out
The 2021 Lexus RX continues to be a sought-after luxury SUV due to its exceptional reliability and upscale features. Owners appreciate its smooth handling and comfortable ride, making it ideal for both city driving and long trips. This model year also introduces enhancements in its safety technology, including new standard safety systems that add to the peace of mind for drivers. Despite its strengths, some users note a lack of cargo space and desire for more responsive brakes in comparison to sportier vehicles. Overall, the 2021 Lexus RX stands out for its elegant design, luxurious interior, and impressive reputation for reliability, appealing to those seeking a comfortable and dependable luxury SUV.
Other model years to consider
- Average price: $44,227.00
- Good/great deal percentage: 83.0%
- User rating: 5 / 5
- Total listings: 100
- Average price: $34,373.00
- Good/great deal percentage: 84.3%
- User rating: 4.88 / 5
- Total listings: 51
- Average price: $37,593.00
- Good/great deal percentage: 101.2%
- User rating: 4.75 / 5
- Total listings: 84
This analysis is based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
Relevant articles

Best Lexus Deals in April 2026
Leasing a Lexus can be a great way to get into a new car from one of the most popular luxury brands at a more affordable monthly rate. Here are the best deals we've found this month on Lexus vehicles.

The Best Used Luxury SUVs in 2026
No matter how you look at it, today’s automotive market is dominated by SUVs, in particular compact SUVs. The "not-a-minivan" family haulers have become so popular and profitable for automakers that many have stopped making cars in favor of building more SUVs in recent years.

The Best Used Midsize SUVs in 2026
Family-friendly SUVs are more expensive than ever, but you can still find good deals if you know where to look. Here, we’ve got used midsize SUV recommendations at four price points under $40,000.
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 FWD | $45,220 |
| 350 AWD | $46,620 |
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends








