Used 2021 Lexus IS for Sale nearWashington, DC
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,535
- Stock #:
- 056455
- VIN:
- JTHGZ1B29N5056455


Sponsored by Merlex Auto Group
2022 Lexus IS
350 F Sport RWD
85,535 mi
$32,965
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 115,004
- Stock #:
- 116414
- VIN:
- JTHCA1D29M5116414

-$600
Sponsored Listing
2021 Lexus IS
300 RWD
115,004 mi
$22,366
$21,766
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 70,273
- Stock #:
- K70083B
- VIN:
- JTHG81F28L5041262

Sponsored Listing
2020 Lexus IS
300 AWD
70,273 mi
$27,797
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 51,477
- Stock #:
- T5048332
- VIN:
- JTHD81F28N5048332

2022 Lexus IS
300 AWD
51,477 mi
$34,491
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,997
- Stock #:
- 50383A
- VIN:
- JTHGZ1B22N5050383

2022 Lexus IS
350 F Sport RWD
64,997 mi
$35,744
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 70,273
- Stock #:
- K70083B
- VIN:
- JTHG81F28L5041262

2020 Lexus IS
300 AWD
70,273 mi
$27,797
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Ultra White
- Interior color:
- Circuit Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 51,191
- Stock #:
- N5026107
- VIN:
- JTHGZ1E27N5026107

2022 Lexus IS
350 F SPORT 2 AWD
51,191 mi
$39,000
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 115,004
- Stock #:
- 116414
- VIN:
- JTHCA1D29M5116414

-$600
2021 Lexus IS
300 RWD
115,004 mi
$22,366
$21,766
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 42,055
- Stock #:
- 29138748
- VIN:
- JTHGZ1E25N5023299

2022 Lexus IS
350 F SPORT AWD
42,055 mi
$43,247
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 105,060
- Stock #:
- B120819
- VIN:
- JTHDA1D23N5120819

2022 Lexus IS
300 RWD
105,060 mi
$26,563
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Blue
- Transmission:
- 6-Speed Automatic
- Mileage:
- 47,886
- Stock #:
- 1LC2449
- VIN:
- JTHG81F27L5042449

2020 Lexus IS
300 AWD
47,886 mi
$32,248
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black Metallic Trim Eb21
- Transmission:
- Automatic
- Mileage:
- 107,103
- Stock #:
- 4229
- VIN:
- JTHAA1D29N5119614

2022 Lexus IS
300 RWD
107,103 mi
$24,705
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 86,734
- Stock #:
- 036741
- VIN:
- JTHGZ1B22L5036741

2020 Lexus IS
350 RWD
86,734 mi
$27,570
CarGurus Analysis:
2021 Lexus IS
With 68 currently listed for sale and an average price of $28,241, 38.2% of 2021 Lexus IS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2021 Lexus IS listings on CarGurus are accident free.
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 74,076
- Stock #:
- KWGPL5042155
- VIN:
- JTHD81F28L5042155

2020 Lexus IS
300 AWD
74,076 mi
$28,495
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 95,656
- Stock #:
- 021273
- VIN:
- JTHGZ1E21M5021273

2021 Lexus IS
350 F Sport AWD
95,656 mi
$30,764
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,535
- Stock #:
- 056455
- VIN:
- JTHGZ1B29N5056455

2022 Lexus IS
350 F Sport RWD
85,535 mi
$32,965
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red W/Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 49,369
- Stock #:
- J049445U
- VIN:
- JTHD81F24N5049445

2022 Lexus IS
300 AWD
49,369 mi
$36,419
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Interior color:
- Circuit Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 112,115
- Stock #:
- HP7263
- VIN:
- JTHGZ1E25N5025943
2022 Lexus IS
350 F SPORT 2 AWD
112,115 mi
$32,549
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Other
- Transmission:
- 8-Speed Automatic
- Mileage:
- 79,867
- Stock #:
- 037718
- VIN:
- JTHGZ1B2XM5037718

2021 Lexus IS
350 F Sport RWD
79,867 mi
$34,446
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 68,379
- Stock #:
- M5018473
- VIN:
- JTHGZ1E25M5018473

2021 Lexus IS
350 F Sport AWD
68,379 mi
$37,436
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 34,814
- Stock #:
- 1139
- VIN:
- JTHGZ1B25N5049647

2022 Lexus IS
350 F Sport RWD
34,814 mi
$40,288
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 97,974
- Stock #:
- MAS-114114
- VIN:
- JTHAA1D2XM5114114

2021 Lexus IS
300 RWD
97,974 mi
$27,258
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Blue
- Transmission:
- 8-Speed Automatic
- Mileage:
- 111,361
- Stock #:
- 106777
- VIN:
- JTHGA1D26L5106777

Sponsored Listing
2020 Lexus IS
300 RWD
111,361 mi
$20,683
CarGurus Analysis: 2021 Lexus IS
overall

Summary
With 68 currently listed for sale and an average price of $28,241, 38.2% of 2021 Lexus IS listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2021 Lexus IS listings on CarGurus are accident free.
Why it stands out
The 2021 Lexus IS stands out as a compact luxury sports sedan that leans hard into style and driving enjoyment. Lexus describes it as entering a new generation and drawing lessons from the LC and RC, with the goal of appealing to enthusiast drivers and luxury buyers who might otherwise look to German rivals first. That positioning gives the car a more focused personality than a typical comfort-first sedan, and it helps explain why its design and handling are such central parts of its appeal.
What makes the 2021 IS especially distinctive is the combination of stylish design, multiple powertrain options, and strong handling. Those strengths make it attractive to buyers who want a sedan that feels more engaging than merely practical. At the same time, it is not without drawbacks: the base engine is described as underwhelming, the transmission as irritating, and the technology as outdated. Owner feedback broadly reinforces the car’s sporty feel, luxurious atmosphere, and safety features, while also echoing complaints about missing modern tech conveniences and fuel efficiency concerns with the smaller engine.
Other model years to consider
- 2022 Lexus IS
- Average price: $32,744
- Good/great deal percentage: 36.8%
- User rating: 5 / 5
- Total listings: 114
- 2023 Lexus IS
- Average price: $36,966
- Good/great deal percentage: 33.8%
- User rating: 4.8 / 5
- Total listings: 139
- 2015 Lexus IS
- Average price: $18,300
- Good/great deal percentage: 25.9%
- User rating: 4.6 / 5
- Total listings: 112
Similar models to consider
- 2021 BMW 3 Series
- Average price: $24,103
- Good/great deal percentage: 34.9%
- User rating: 5 / 5
- Total listings: 255
- 2021 Audi A4
- Average price: $24,356
- Good/great deal percentage: 23.5%
- User rating: 4.75 / 5
- Total listings: 51
- 2021 Mercedes-Benz C-Class
- Average price: $24,615
- Good/great deal percentage: 31.6%
- User rating: 5 / 5
- Total listings: 256
This analysis is based on CarGurus' proprietary market data from October 12, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
See more price trends2021 Lexus IS Pricing Analysis: Washington, DC Market Report
Pricing in Nearby Cities
Market Area: Washington, DC
Key Insights
- Highest-Price Market: The Hanover, PA market leads with an average price of $38,995, indicating a premium demand in that area.
- Best Value: The Fredericksburg, VA market offers the lowest average price at $28,213, presenting a significant opportunity for budget-conscious shoppers.
- Inventory Drives Stability: The Newark, DE market has the most listings at 67, suggesting a robust supply that may help stabilize prices in the region.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Newark, DE | 67 | $37,203 |
| Hanover, PA | 66 | $38,995 |
| Lancaster, PA | 66 | $38,942 |
| Fredericksburg, VA | 63 | $28,213 |
| Manassas, VA | 61 | $28,213 |
| Baltimore, MD | 61 | $28,324 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 300 RWD trim is the most popular with 65 listings, indicating strong consumer preference for this configuration.
- Premium Spread: The 350 F Sport AWD trim, priced at $44,950, represents the highest MSRP, highlighting a significant premium for performance features.
- Drivetrain Effect: The average price for AWD trims is notably higher, with the 300 AWD priced at $41,050, reflecting the added value perceived by consumers for all-wheel drive capabilities.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 300 RWD | 65 | $39,050 | RWD | 2.0L 241 hp I4 |
| 350 F Sport RWD | 37 | $42,950 | RWD | 3.5L 311 hp V6 |
| 300 AWD | 59 | $41,050 | AWD | 3.5L 260 hp V6 |
| 350 F Sport AWD | 22 | $44,950 | AWD | 3.5L 311 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2026 model year shows a 12.1% premium over its starting MSRP, indicating strong demand for newer models.
- Depreciation Curve: The 2016 model year has experienced the steepest depreciation at -56.6%, suggesting significant value loss over time.
- Best Value Sweet Spot: The 2021 model year, priced at an average of $28,213, represents a compelling value for buyers looking for a balance between price and features.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2026 | $45,500 | $51,000 | +12.1% |
| 2025 | $40,535 | $48,562 | +19.8% |
| 2024 | $40,085 | $45,323 | +13.1% |
| 2023 | $40,085 | $37,247 | -7.1% |
| 2022 | $39,125 | $32,683 | -16.5% |
| 2021 | $39,050 | $28,213 | -27.8% |
| 2020 | $38,560 | $23,609 | -38.8% |
| 2019 | $38,560 | $24,085 | -37.5% |
| 2018 | $38,210 | $20,657 | -45.9% |
| 2017 | $37,825 | $20,950 | -44.6% |
| 2016 | $37,325 | $16,206 | -56.6% |
These recommendations are based on CarGurus' proprietary market data from October 14, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus IS cost?
| Metric | Value |
|---|---|
| Current Average Price | $34,517 |
| Year-Round Low | $33,075 |
| Year-Round High | $35,491 |
| Average Price a Year Ago | $34,153 |
| Change vs. Last Year | +1.07% |
Prices are up 1.07% year-over-year — a sign of continued demand for this model year.
There are 508 listings available, which gives you a meaningful amount of inventory to compare.
Is the 2021 Lexus IS a good car?
Yes — 4.62/5 owners rate it, and the expert rating is 7.33/10. The model scores 8/10 across Look and feel and Cost effectiveness.
Owners consistently praise the stylish design, sporty feel, luxurious atmosphere, handling, and value for money. The overview also frames it as a compact luxury sports sedan aimed at enthusiast drivers and luxury buyers who want something more engaging than a typical comfort-first sedan.
The main trade-offs are the underwhelming base engine, the irritating transmission, and outdated technology. That said, the car’s sporty personality and premium feel line up well with buyers who care more about driving enjoyment than maximum practicality.
With 35.8% of listings marked as good or great deals, you still have room to shop selectively.
Is the 2021 Lexus IS reliable?
Owners rate it 4.62/5, a strong signal of long-term satisfaction.
The owner summary points to a car that feels dependable, with buyers highlighting its strong safety features, luxurious feel, and overall satisfaction over time. The expert notes also emphasize Lexus’ reputation for quality and reliability, which supports the idea that this is a car you can count on for the long haul.
The performance notes add to that impression by describing the car as crisp, precise, and balanced, which suggests a well-sorted chassis rather than a fragile one. The cost-effectiveness notes also reinforce Lexus’ quality-and-reliability reputation.
For used buyers, the main long-term ownership risk is less about basic durability and more about living with the car’s dated tech and powertrain compromises.
What should I look for when buying a used 2021 Lexus IS?
At 71.9% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a careful inspection of bodywork, panel alignment, and repair quality. Because accident history is common enough to matter, condition should be a bigger part of your decision than mileage alone.
Pay close attention to how the transmission behaves on a test drive, and make sure the infotainment and driver-assistance features work as expected. If you’re comparing multiple listings, focus on the one that feels cleanest mechanically and cosmetically, not just the one with the lowest price.
Key things to evaluate:
- Trim level: The IS comes in four flavors, and the base IS 300 RWD is the least expensive entry point. The IS 350 RWD F Sport and IS 350 AWD F Sport add a more aggressive setup and are the trims most clearly aimed at buyers who want the sportiest feel.
- Powertrain: The IS 300 RWD uses a 2.0-liter turbo four-cylinder with 241 horsepower and 258 pound-feet of torque, while the IS 300 AWD uses a 3.5-liter V6 with 260 hp and 236 lb-ft. The IS 350 models use the same V6 tuned to 311 hp and 280 lb-ft. RWD models get an eight-speed automatic, while AWD models get a six-speed automatic.
- Safety package: Lexus Safety System+ 2.5 is standard, and it includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. Standard blind-spot monitoring with rear cross-traffic alert is also included.
- Infotainment: The touchscreen infotainment system supports Android Auto and Apple CarPlay. Lexus Enform Safety Connect comes with a three-year trial, Service Connect comes with a 10-year complimentary subscription, and Lexus Enform Remote is free for three years.
- Fuel efficiency: The IS 300 RWD is rated at 21 mpg city, 31 mpg highway, and 25 mpg combined. The IS 300 AWD is rated at 19/26/22, the IS 350 RWD at 20/28/23, and the IS 350 AWD at 19/26/22.
Which 2021 Lexus IS trim should I buy?
The 2021 Lexus IS is offered in 4 trim levels: IS 300 RWD, IS 300 AWD, IS 350 RWD F Sport, IS 350 AWD F Sport.
Here's the short version:
- IS 300 RWD: This is the best-value starting point if you want the lowest entry price and the standard rear-wheel-drive setup. It gives you the core IS experience without stepping up to the pricier V6 models.
- IS 300 AWD: Choose this if you want the added traction of all-wheel drive and are willing to pay more for it. It makes sense if your priorities lean toward all-weather confidence rather than maximum performance.
- IS 350 RWD F Sport: This is the strongest pick if you want the most engaging balance of power and rear-drive character. It adds the more potent V6 and is the trim most likely to satisfy enthusiast buyers.
- IS 350 AWD F Sport: Pick this if you want the top-end V6 with all-wheel-drive traction. It is the priciest version, so it suits you best if you want the most capability and are comfortable paying for it.
Lexus Safety System+ 2.5 is standard across the lineup, so you do not need to move up a trim to get the core safety suite.
Is now a good time to buy a used 2021 Lexus IS?
This looks like a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.
- Deal availability: 35.8% of listings are priced as good or great deals.
- Inventory: There are 508 listings available.
- Price trend: Prices are up 1.07% year-over-year.
- Clean inventory: 71.9% of listings are accident-free.
If you find a listing below $33,075, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus IS's resale value?
The current average of $34,517 sits slightly above last year's $34,153.
That modest increase suggests the market has held up reasonably well for this model year. If you buy well and keep the car in clean condition, you should have a decent chance of preserving value better than a weaker-priced or less desirable alternative.
The year-over-year gain also signals that demand has remained steady enough to support pricing. For a future seller, that means a clean, well-kept example should still attract interest, especially if it has the right trim and a strong service history.
Vehicles with strong owner satisfaction ratings, like this model year's 4.62/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus IS safe?
The 2021 Lexus IS hasn’t yet been rated for crashworthiness by the Insurance Institute for Highway Safety (IIHS), nor has it received an overall rating from the National Highway Traffic Safety Administration (NHTSA).
It earns a 7/10 safety score from our experts.
Lexus Safety System+ 2.5 is standard, and it includes pre-collision system with pedestrian detection, low-light pedestrian detection, daytime bicyclist detection, left-turn intersection support, lane-departure warning with steering assist, road-sign recognition, enhanced lane-tracing assist, full-speed dynamic adaptive cruise control, and intelligent high beams. Standard blind-spot monitoring with rear cross-traffic alert, a backup camera with dynamic gridlines, and Lexus Enform Safety Connect are also included.
The main caveat is that the car lacks published crash-test results in the source data, so you should lean more heavily on the standard safety equipment and the condition of any used example you consider.
Should I buy a 2021 Lexus IS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 35.8% of listings are priced as good or great deals.
- At 71.9% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices are up 1.07% year-over-year.
- Owners rate it 4.62/5 — a strong satisfaction signal.
- The 2021 model introduces the new generation’s sharper design, updated infotainment, and standard Lexus Safety System+ 2.5.
Consider the 2022 if:
- At $37,304, the 2022 costs more than the current year's $34,517 average.
- It adds a significant performance boost, including the new IS 500 F Sport Performance V8.
The bottom line: If you want the better value and a broader pool of listings, the 2021 is the smarter starting point. If you care most about stronger performance and can stretch your budget, the 2022 is the more exciting choice.
These recommendations are based on CarGurus' proprietary market data from October 13, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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