Used 2018 Mercedes-Benz S-Class for Sale near Missouri

Compare 2018 Mercedes-Benz S-Class Trims

The S-Class offers a range of luxury trims from budget-friendly options to high-performance models, catering to various preferences and needs.

• Starting at $24,898
• Best MPG/MPGe: 19 city / 28 hwy
• Most Popular: S 560 4MATIC AWD

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

Missing data displayed as "—".

Trim Deep Dives

S 450 RWD — "Who It's For"

The S 450 RWD is the pick for shoppers who want luxury features without the higher price tag of AWD models.

• Avg. market price: $25,856 (updated weekly)
• MPG/MPGe: 19 city / 28 hwy
• Inventory: 63 listings — lower availability; may limit negotiating room
• View S 450 RWD listings

S 450 4MATIC AWD — "Who It's For"

The S 450 4MATIC AWD is the choice for those wanting all-wheel drive without a significant price increase.

• Avg. market price: $24,898 (updated weekly)
• MPG/MPGe: 18 city / 28 hwy
• Inventory: 51 listings — lower availability; may limit negotiating room
• View S 450 4MATIC AWD listings

S 560 RWD — "Who It's For"

The S 560 RWD is ideal for buyers seeking a powerful V8 engine with a traditional luxury sedan experience.

• Avg. market price: $32,073 (updated weekly)
• MPG/MPGe: 17 city / 27 hwy
• Inventory: 123 listings — lower availability; may limit negotiating room
• View S 560 RWD listings

S 560 4MATIC AWD — "Who It's For"

The S 560 4MATIC AWD is perfect for those wanting a sporty luxury sedan with all-wheel drive capabilities.

• Avg. market price: $32,822 (updated weekly)
• MPG/MPGe: 17 city / 27 hwy
• Inventory: 125 listings — lower availability; may limit negotiating room
• View S 560 4MATIC AWD listings

S 63 AMG 4MATIC AWD — "Who It's For"

The S 63 AMG 4MATIC AWD is for buyers who desire high-performance luxury without compromise.

• Avg. market price: $53,012 (updated weekly)
• MPG/MPGe: 17 city / 26 hwy
• Inventory: 20 listings — lower availability; may limit negotiating room
• View S 63 AMG 4MATIC AWD listings

Maybach S 560 4MATIC AWD — "Who It's For"

The Maybach S 560 4MATIC AWD is the ultimate choice for those seeking unparalleled luxury and advanced features.

• Avg. market price: $62,959 (updated weekly)
• MPG/MPGe: 16 city / 25 hwy
• Inventory: 12 listings — lower availability; may limit negotiating room
• View Maybach S 560 4MATIC AWD listings

Trim Recommendations

Most Popular — S 560 4MATIC AWD

With 125 active listings, the S 560 4MATIC AWD is the clear volume leader in the lineup.

Browse S 560 4MATIC AWD listings

Best Budget Option — S 450 4MATIC AWD

At $24,898 avg market price — below the lineup median of $32,447 — it's the most accessible entry point.

Browse S 450 4MATIC AWD listings

Best for Fuel Economy — S 450 RWD

The S 450 RWD offers the best fuel efficiency in the lineup with 19/28 MPG.

Browse S 450 RWD listings

These recommendations are based on CarGurus' proprietary market data from November 12, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2018 Mercedes-Benz S-Class cost?

Prices have softened 7.64% compared to this time last year, making it a favorable time to shop this model year.

There are 690 listings available, which gives you a solid pool of options to compare.

Is the 2018 Mercedes-Benz S-Class a good car?

Yes — the 2018 Mercedes-Benz S-Class earns a 4.8/5 user rating, which points to strong owner satisfaction. Drivers consistently praise its luxurious interior, advanced technology, smooth performance, high-quality craftsmanship, and spacious cabin. That makes it especially appealing if you want a flagship luxury sedan with a refined feel and a deep feature set. With 34.9% of listings marked as good or great deals, you have a meaningful chance to find a competitive price.

Is the 2018 Mercedes-Benz S-Class reliable?

Owners rate it 4.8/5, a strong signal of long-term satisfaction.

Drivers describe it as dependable in the ways that matter most for a luxury flagship, especially when it comes to smooth operation, craftsmanship, and the confidence that comes from a well-executed cabin and drivetrain. The strongest reliability takeaway is that satisfied owners tend to keep these cars in service and appreciate them over time, which supports the idea that a carefully maintained example can be a solid used purchase. For you, the main long-term ownership risk is less about the model’s appeal and more about making sure the specific car has been well cared for.

What should I look for when buying a used 2018 Mercedes-Benz S-Class?

At 63.2% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report so you can separate clean examples from cars with prior damage or repeated claims. After that, prioritize a thorough pre-purchase inspection, with extra attention to body condition, interior wear, and how well the car’s luxury features operate. Because this is a high-end sedan, you’ll want to focus on overall condition and maintenance quality rather than just mileage alone.

Is now a good time to buy a used 2018 Mercedes-Benz S-Class?

This looks like a moderate market for selective buyers, with enough inventory to shop carefully and enough deal activity to reward patience.

• Deal availability: 34.9% of listings are priced as good or great deals.
• Inventory: There are 690 listings available.
• Price trend: Prices have softened 7.64% compared with last year.
• Clean inventory: 63.2% of listings are accident-free.

If you find a listing below $33,774, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2018 Mercedes-Benz S-Class's resale value?

The current average of $33,810 sits slightly below last year's $36,606.

That price movement suggests the market has already adjusted downward, which can help you buy at a more favorable point if you plan to keep the car for a while. For a future seller, the softer pricing means resale upside may be more limited than it was a year ago, so condition and documentation matter even more. A well-kept example with strong ownership history should still attract interest, especially in a segment where buyers expect refinement and prestige.

Vehicles with strong owner satisfaction ratings, like this model year's 4.8/5, tend to retain buyer demand, which supports resale value over time.

Should I buy a 2018 Mercedes-Benz S-Class or consider a different year?

If you're weighing the 2018 against nearby model years, here's how to think about it:

Choose the 2018 if:

• 34.9% of listings are priced as good or great deals.
• At 63.2% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have softened 7.64% compared with last year.
• Owners rate it 4.8/5 — a strong satisfaction signal.

The bottom line: You should lean toward the 2018 if you want a well-liked flagship sedan at a softer price point than it carried a year ago. If your priority is maximizing value, the 2018 is a strong place to shop; if you want to stretch your budget further, a nearby year with a lower average price may be worth comparing, but you’ll want to balance that against condition and deal quality.

How does the 2018 Mercedes-Benz S-Class compare to the 2018 BMW 7 Series?

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.