Used GMC Sierra 2500HD Denali for Sale near Mississippi

Filters (3)

Location:

Only show listings in MS?

Include delivery listings?

340 vehicles found

Shop with transparent pricing.

Only show listings that include dealer fees
Year:
2025
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
470 hp 6.6L V8 Biodiesel
Exterior color:
Onyx Black
Fuel type:
Biodiesel
Interior color:
Atmosphere/Brownstone
Transmission:
Automatic
Mileage:
30,449
Stock #:
CG49803T
VIN:
1GT4UREY4SF349803
Onyx Black 2025 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic
New arrival
Walt Massey Chevrolet GMC Columbia

Sponsored by Walt Massey Chevrolet GMC Columbia

2025 GMC Sierra 2500HD

Denali Crew Cab 4WD

30,449 mi

Columbia, MS
77 mi away
Fair Deal

$74,027

Year:
2020
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
401 hp 6.6L V8
Exterior color:
Onyx Black
Fuel type:
Gasoline
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
142,500
Stock #:
LF236986
VIN:
1GT49RE77LF236986
Onyx Black 2020 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic
New arrival

Sponsored Listing

2020 GMC Sierra 2500HD

Denali Crew Cab 4WD

142,500 mi

Brandon, MS
9 mi away
Good Deal

$42,425

Year:
2018
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
Gray
Fuel type:
Biodiesel
Transmission:
Automatic
Mileage:
117,232
Stock #:
6734
VIN:
1GT12UEY8JF238004
Gray 2018 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2018 GMC Sierra 2500HD

Denali Crew Cab SB 4WD

117,232 mi

Florence, MS
9 mi away
Fair Deal

$46,434

Year:
2021
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
Black
Fuel type:
Biodiesel
Interior color:
Black
Transmission:
Automatic
Mileage:
75,190
Stock #:
177741
VIN:
1GT49REY7MF177741
Black 2021 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2021 GMC Sierra 2500HD

Denali Crew Cab 4WD

75,190 mi

Home delivery from Pelham, AL
Price includes $530 shipping
Fair Deal

$59,725

Year:
2025
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
470 hp 6.6L V8 Biodiesel
Exterior color:
[GXD] Sterling Metallic
Fuel type:
Biodiesel
Interior color:
Atmosphere/Brownstone
Transmission:
Automatic
Mileage:
77,148
Stock #:
26437
VIN:
1GT4UREYXSF101006
[GXD] Sterling Metallic 2025 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2025 GMC Sierra 2500HD

Denali Crew Cab 4WD

77,148 mi

Home delivery from Searcy, AR
Free home delivery
Fair Deal

$65,000

Year:
2021
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White Frost Tricoat
Fuel type:
Biodiesel
Interior color:
Gray (Dark Walnut/Dark Ash Grey)
Transmission:
Automatic
Mileage:
120,874
Stock #:
6471
VIN:
1GT49REY0MF236287
White Frost Tricoat 2021 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2021 GMC Sierra 2500HD

Denali Crew Cab 4WD

120,874 mi

Home delivery from Mansfield, TX
Price includes $608 shipping
Fair Deal

$51,032

Year:
2016
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
360 hp 6L V8 Flex Fuel Vehicle
Exterior color:
Summit White
Fuel type:
Flex Fuel Vehicle
Interior color:
Jet Black
Transmission:
6-Speed Automatic Overdrive
Mileage:
115,840
Stock #:
272834
VIN:
1GT12UEGXGF272834
Summit White 2016 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic Overdrive
Price drop

-$651

 

2016 GMC Sierra 2500HD

Denali Crew Cab SB 4WD

115,840 mi

Home delivery from Kenner, LA
Price includes $242 shipping
Good Deal

$32,778

$32,126

Year:
2021
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White
Fuel type:
Biodiesel
Interior color:
Black
Transmission:
Automatic
Mileage:
102,729
Stock #:
107752
VIN:
1GT19REYXMF107752
White 2021 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2021 GMC Sierra 2500HD

Denali Crew Cab 4WD

102,729 mi

Home delivery from Marietta, GA
Price includes $526 shipping
Good Deal

$51,196

Year:
2020
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Exterior color:
Onyx Black
Interior color:
Jet Black
Transmission:
Automatic
Mileage:
105,652
Stock #:
104001
VIN:
1GT49REY0LF104001
Onyx Black 2020 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2020 GMC Sierra 2500HD

Denali Crew Cab 4WD

105,652 mi

Home delivery from Kernersville, NC
Price includes $951 shipping
Fair Deal

$50,578

Year:
2021
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White
Fuel type:
Biodiesel
Transmission:
Automatic
Mileage:
139,385
Stock #:
71947
VIN:
1GT49REY8MF300267
White 2021 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2021 GMC Sierra 2500HD

Denali Crew Cab 4WD

139,385 mi

Hattiesburg, MS
86 mi away
Fair Deal

$47,299

Year:
2021
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White
Fuel type:
Biodiesel
Interior color:
Brown
Transmission:
6-Speed Automatic
Mileage:
158,583
Stock #:
271645
VIN:
1GT49REYXMF271645
White 2021 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic
Price drop

-$1,000

 

2021 GMC Sierra 2500HD

Denali Crew Cab 4WD

158,583 mi

Hattiesburg, MS
95 mi away
Good Deal

$44,189

$43,189

Year:
2024
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
470 hp 6.6L V8 Biodiesel
Exterior color:
Onyx Black
Fuel type:
Biodiesel
Interior color:
Jet Black
Transmission:
Automatic
Mileage:
40,097
Stock #:
4UT11434
VIN:
1GT49REY5RF221808
Onyx Black 2024 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic
Price drop

-$1,600

 

2024 GMC Sierra 2500HD

Denali Crew Cab 4WD

40,097 mi

Hattiesburg, MS
81 mi away
Great Deal

$70,283

$68,683

Year:
2020
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
Red Quartz Tintcoat
Fuel type:
Biodiesel
Interior color:
Jet Black
Transmission:
Automatic
Mileage:
39,226
Stock #:
P82679
VIN:
1GT49REY7LF282679
Red Quartz Tintcoat 2020 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2020 GMC Sierra 2500HD

Denali Crew Cab 4WD

39,226 mi

Home delivery from Tulsa, OK
Price includes $626 shipping
Good Deal

$58,968

Year:
2020
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
401 hp 6.6L V8
Exterior color:
Onyx Black
Fuel type:
Gasoline
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
142,500
Stock #:
LF236986
VIN:
1GT49RE77LF236986
Onyx Black 2020 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic
New arrival

 

2020 GMC Sierra 2500HD

Denali Crew Cab 4WD

142,500 mi

Brandon, MS
9 mi away
Good Deal

$42,425

Year:
2019
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White
Fuel type:
Biodiesel
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
109,957
Stock #:
NLNM1184
VIN:
1GT12SEY7KF114733
White 2019 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic

 

2019 GMC Sierra 2500HD

Denali Crew Cab 4WD

109,957 mi

Home delivery from Mandeville, LA
Free home delivery
Great Deal

$41,896

Year:
2024
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
401 hp 6.6L V8
Exterior color:
Sterling Metallic
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
36,920
Stock #:
DU4620
VIN:
1GT49RE78RF233197
Sterling Metallic 2024 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2024 GMC Sierra 2500HD

Denali Crew Cab 4WD

36,920 mi

Home delivery from Delray Beach, FL
Price includes $915 shipping
Fair Deal

$67,211

Year:
2016
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
397 hp 6.6L V8 Diesel
Exterior color:
Black
Fuel type:
Diesel
Interior color:
Black
Transmission:
6-Speed Automatic Overdrive
Mileage:
165,330
Stock #:
655
VIN:
1GT12UE84GF236646
Black 2016 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic Overdrive

 

2016 GMC Sierra 2500HD

Denali Crew Cab SB 4WD

165,330 mi

Home delivery from Casselberry, FL
Price includes $872 shipping
Great Deal

$31,270

Year:
2024
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
470 hp 6.6L V8 Biodiesel
Exterior color:
White Frost Tricoat
Fuel type:
Biodiesel
Mileage:
41,962
Stock #:
TRF339976
VIN:
1GT49REY2RF339976
White Frost Tricoat 2024 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive

 

2024 GMC Sierra 2500HD

Denali Crew Cab 4WD

41,962 mi

Home delivery from Houston, TX
Price includes $738 shipping
Great Deal

$64,960

Year:
2022
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White Frost Tricoat
Fuel type:
Biodiesel
Interior color:
Jet Black
Transmission:
Automatic
Mileage:
48,153
Stock #:
1GT1713
VIN:
1GT49REY8NF301713
White Frost Tricoat 2022 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2022 GMC Sierra 2500HD

Denali Crew Cab 4WD

48,153 mi

Home delivery from Greensboro, NC
Price includes $899 shipping
Good Deal

$61,793

Year:
2017
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White
Fuel type:
Biodiesel
Interior color:
Cocoa/Dark Sand, Perforated Leather-Appointed Seat
Transmission:
Automatic
Mileage:
81,940
Stock #:
THF118431
VIN:
1GT12UEY5HF118431
White 2017 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

 

2017 GMC Sierra 2500HD

Denali Crew Cab SB 4WD

81,940 mi

Home delivery from Aurora, CO
Price includes $1,442 shipping
Good Deal

$46,820

Year:
2022
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
401 hp 6.6L V8
Exterior color:
Onyx Black
Fuel type:
Gasoline
Interior color:
Jet Black
Transmission:
6-Speed Automatic
Mileage:
26,889
Stock #:
F169169
VIN:
1GT49RE78NF169169
Onyx Black 2022 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic

 

2022 GMC Sierra 2500HD

Denali Crew Cab 4WD

26,889 mi

Home delivery from Defiance, OH
Price includes $1,398 shipping
Great Deal

$57,240

Year:
2019
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
Summit White
Fuel type:
Biodiesel
Interior color:
Jet Black
Transmission:
6-Speed Automatic
Mileage:
142,298
Stock #:
268521A
VIN:
1GT12SEY1KF151633
Summit White 2019 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive 6-Speed Automatic

 

2019 GMC Sierra 2500HD

Denali Crew Cab 4WD

142,298 mi

Home delivery from Metairie, LA
Free home delivery
Good Deal

$41,473

Year:
2016
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
397 hp 6.6L V8 Diesel
Exterior color:
Summit White
Fuel type:
Diesel
Interior color:
JET BLACK, PERFORATED LEATHER-APPOINTED SEAT TRIM
Transmission:
Automatic
Mileage:
158,083
Stock #:
26790B
VIN:
1GT12UE80GF214160
Summit White 2016 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2016 GMC Sierra 2500HD

Denali Crew Cab SB 4WD

158,083 mi

Home delivery from West Plains, MO
Price includes $792 shipping
Good Deal

$35,780

Year:
2020
Make:
GMC
Model:
Sierra 2500HD
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
6.6L V8 Biodiesel
Exterior color:
White Frost Tricoat
Fuel type:
Biodiesel
Interior color:
JET BLACK
Transmission:
Automatic
Mileage:
102,822
Stock #:
G22502
VIN:
1GT49REY3LF137803
White Frost Tricoat 2020 GMC Sierra 2500HD Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2020 GMC Sierra 2500HD

Denali Crew Cab 4WD

102,822 mi

Brandon, MS
10 mi away
Fair Deal

$53,279

Overview

GMC introduced the luxurious Denali trim to its pickup catalog in the early 2000s and has expanded it to its heavy-duty truck like. The GMC Sierra 2500HD Denali is available only with four-wheel drive and can be had with a long or standard bed. No matter how it’s configured, the truck sports a crew cab body style. As a flagship trim of one of GMC’s most popular trucks, the 2500HD Denali gets the best features, an upscale interior, massive capability, and a heavy price tag to match.

Key Features

  • Standard 6.6-liter gas engine, available diesel
  • Six-speed heavy-duty transmission
  • Four-wheel drive
  • Trailering assistance functions
  • Available Allison ten-speed transmission

Pricing Details

The 2022 GMC Sierra 2500HD Denali starts at $71,395. Stepping up to the 6.6-liter turbodiesel option adds a whopping $11,000 to the price tag but brings 910 pound-feet of torque and an Allison transmission. Used examples on CarGurus range from $19,587.00 to $99,621.00 with an average price of $24,061.87. Buyers can go wild with options, such as the $2,990 Black Diamond Edition, which adds a Kicker audio system in the tailgate. The $1,770 Denali Ultimate Package brings a sunroof, rear camera mirror system, and a head-up display. GMC also offers a plethora of accessories, such as bike racks, hitch carriers, and cargo management components.

Specifications

Performance

  • Engine

    Standard 6.6-liter V8

  • Transmission

    Six-speed automatic

  • Drivetrain

    Four-wheel drive

  • Horsepower/Torque

    401 hp/464 lb-ft

  • 0-60 mph

    7.5 seconds (estimated)

  • MPG

    N/A (HD trucks are not subject to EPA fuel economy measurements)

  • Curb weight

    6,642 pounds

Dimensions

  • wheelbase

    158.94 inches (standard bed)

  • length

    250.08 inches (standard bed)

  • width

    250.08 inches (standard bed)

  • height

    79.82 inches

*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.

Relevant articles

Best Truck Lease Deals in September 2026
CarGurus Editorial Team

Best Truck Lease Deals in September 2026

Leasing a truck can be a great way to get into one of the latest models, with the best technology, at a more affordable monthly price. Here are the best deals we've found this month.

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Jill Ciminillo

2026 GMC Sierra 2500HD Pricing, Specs, and Release Date

Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Chris Teague

2025 GMC Sierra 2500HD Pricing, Specs, and Release Date

Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.

GMC Sierra 2500HD Denali in MississippiGMC Sierra 2500HD SLT in MississippiGMC Sierra 2500HD SLE in MississippiGMC Sierra 2500HD Base in MississippiGMC Sierra 2500HD Work Truck in MississippiGMC Sierra 2500HD SLE1 in MississippiGMC Sierra 2500HD SLE2 in Mississippi

GMC Sierra 2500HD in Jackson MSGMC Sierra 2500HD in Vicksburg MSGMC Sierra 2500HD in Brookhaven MSGMC Sierra 2500HD in Laurel MSGMC Sierra 2500HD in Greenwood MSGMC Sierra 2500HD in Meridian MSGMC Sierra 2500HD in Hattiesburg MSGMC Sierra 2500HD in Natchez MSGMC Sierra 2500HD in Greenville MS

GMC Sierra 2500HD in MississippiOBS 1990s-era Chevy and Ford Trucks for Sale in MississippiUsed GMC Electric Cars for SaleLifted GMC trucks for sale in MississippiWork Trucks for Sale in MississippiGM Certified Preowned Vehicles for Sale Near Mississippi3/4 Ton Trucks for Sale in Mississippi

2019 GMC Sierra 2500HD Denali in Mississippi2018 GMC Sierra 2500HD Denali in Mississippi2017 GMC Sierra 2500HD Denali in Mississippi2016 GMC Sierra 2500HD Denali in Mississippi2015 GMC Sierra 2500HD Denali in Mississippi2014 GMC Sierra 2500HD Denali in Mississippi

All Used CarsManual Transmission CarsLuxury CarsCars with Red InteriorCheap Manual CarsHybrid CarsSports CarsElectric SUVsCheap TrucksSmall CarsThird Row SUVsThree Quarter Ton TrucksLifted TrucksManual Transmission TrucksDiesel TrucksHybrid SUVsDually TrucksOne Ton TrucksCheap SUVsLifted Ford Trucks4x4 TrucksWork TrucksAWD SUVsFord TrucksChevrolet TrucksToyota TrucksTrucks Under $10,000Cars Under $15,000Sports Cars Under $20,000Trucks Under $20,000Used Sedans for Sale with Low Mileage in MississippiUsed SUVs / Crossovers for Sale with Low Mileage in MississippiUsed Hatchbacks for Sale with Low Mileage in MississippiUsed Convertibles for Sale with Low Mileage in MississippiUsed Vans for Sale with Low Mileage in MississippiUsed Minivans for Sale with Low Mileage in MississippiUsed Pickup Trucks for Sale with Low Mileage in MississippiUsed Coupes for Sale with Low Mileage in MississippiUsed Wagons for Sale with Low Mileage in Mississippi

Express Terry Chevrolet GMC

A better way to discover your best deal

Let us help you find a car you’ll love.