Used Mercedes-Benz S-Class for Sale near San Antonio, TX
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2022 Mercedes-Benz S-Class
Shop 2022 Mercedes-Benz S-Class »With 236 currently listed for sale near San Antonio, TX and an average price of $63,734.00, 24.6% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
91.5% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class introduces advanced hybrid powertrains, including a turbocharged inline six-cylinder and a twin-turbo V8, ensuring an engaging driving experience combined with top-tier luxury and technology.
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4.8 Overall rating
Customers say
The Mercedes-Benz S-Class has consistently impressed drivers with its luxurious feel, outstanding performance, and advanced technology across all model years. Owners particularly appreciate the comfortable and spacious interiors, the smooth ride, and the powerful engines. Many have praised features such as safety innovations and craftsmanship that highlight the brand's commitment to luxury. However, some common concerns among owners include high maintenance costs, issues with technology reliability, and a steep price tag compared to other models. Overall, the S-Class remains a top choice for those seeking a high-end driving experience.
AI generated from the text of customer reviews.
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What people say
Moises S
Reviewed a 2020 Mercedes-Benz S-Class on Jun 20, 2024
the features of an S class are the very reasons that this car is of good value. this is the flagship of Mercedes Benz so there is no comparison.
Randall H
Reviewed a 2021 Mercedes-Benz S-Class on Aug 28, 2025
The car was a lemon. Bought back by mb. And was in an accident. They didn’t divulge this info. Ar has had many tire issues as well. Don’t buy it Way overpriced.
Amy K
Reviewed a 2016 Mercedes-Benz S 550 4MATIC on Aug 27, 2025
Beautiful car lots of luxury features great handling and power!
Chris V
Reviewed a 2021 Mercedes-Benz S-Class on Jun 5, 2024
This car is a driving experience like no other, power, luxury, amenities. I own a dozen cars from square body trucks, sports cars to Cadillacs, this is unrivaled in its ride. I cant wait to get in it each day.
Mercedes-Benz S-Class Trims
| Trim type | MSRP |
|---|---|
| S 500 4MATIC | $119,550 |
| S 580 4MATIC | $130,700 |
| Maybach S 680 4MATIC | $244,400 |
| AMG S 63 E Performance 4MATIC | $189,800 |
| S 580e 4MATIC | $130,400 |
| Maybach S 580 4MATIC | $207,150 |
Mercedes-Benz S-Class Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of Mercedes-Benz S-Class prices has changed over time.
See more price trendsCarGurus recommends the 2022 Mercedes-Benz S-Class

Summary
With 236 currently listed for sale near San Antonio, TX and an average price of $63,734.00, 24.6% of 2022 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz S-Class 4.5 / 5 stars.
91.5% of 2022 S-Class models on CarGurus are accident free.
The 2022 Mercedes-Benz S-Class introduces advanced hybrid powertrains, including a turbocharged inline six-cylinder and a twin-turbo V8, ensuring an engaging driving experience combined with top-tier luxury and technology.
Why it stands out
The 2022 Mercedes-Benz S-Class epitomizes luxury and performance in the full-size sedan segment. Known as an icon in executive transportation, this model provides exceptional comfort intertwined with cutting-edge technology. The S-Class boasts a sleek design, high-quality interiors adorned with premium materials, and a host of advanced features such as the latest MBUX infotainment system, offering an intuitive experience for both drivers and passengers. Its robust performance is complemented by hybrid powertrains that deliver impressive efficiency and power, making it suitable for both leisurely drives and dynamic city commutes. With its reputation for luxury paired with innovative safety features, the S-Class continues to appeal to those seeking the ultimate in driving refinement and prestige.
Other model years to consider
- Average price: $78,741.00
- Good/great deal percentage: 22.2%
- Total listings: 239
- Average price: $27,757.00
- Good/great deal percentage: 25.1%
- User rating: 5 / 5
- Total listings: 167
- Average price: $19,881.00
- Good/great deal percentage: 25.2%
- User rating: 5 / 5
- Total listings: 131
These recommendations are based on CarGurus' proprietary market data from April 28, 2026, CarGurus experts' opinions, and generative AI.
Recent expert test drives

2025 Mercedes-Benz S-Class
- Expert review7/10
- MSRP$117,750-$240,500
- Avg. price$153,660
- User rating5
2023 Mercedes-Benz S-Class
- Expert review9/10
- MSRP$114,500-$229,000
- Avg. price$80,622
- User rating0

2021 Mercedes-Benz S-Class
- Expert review8/10
- MSRP$109,800-$185,400
- Avg. price$68,007
- User rating4
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