Used 2022 RAM 2500 for Sale near South Carolina

Filters (3)

Location:

Only show listings in SC?

Include delivery listings?

528 vehicles found

Shop with transparent pricing.

Only show listings that include dealer fees
Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Gray (Granite Crystal Metallic Clearcoat)
Fuel type:
Diesel
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
44,249
Stock #:
28332A
VIN:
3C6UR5DL3MG645548
Gray (Granite Crystal Metallic Clearcoat) 2021 RAM 2500 Pickup Truck Four-Wheel Drive 6-Speed Automatic
Stateline Chrysler Jeep Dodge

Sponsored by Stateline Chrysler Jeep Dodge

2021 RAM 2500

Big Horn Crew Cab 4WD

44,249 mi

Fort Mill, SC
72 mi away
Fair Deal

$47,637

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
8-Speed Automatic
Mileage:
89,771
Stock #:
13398
VIN:
3C6UR5HJ3NG130396
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

Sponsored Listing

2022 RAM 2500

Tradesman Crew Cab LB 4WD

89,771 mi

Monroe, NC
74 mi away
Good Deal

$28,668

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
White
Fuel type:
Diesel
Interior color:
Gray
Transmission:
Automatic
Mileage:
137,308
Stock #:
2446
VIN:
3C6UR5JL2NG317818
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2022 RAM 2500

Big Horn Crew Cab LB 4WD

137,308 mi

Charlotte, NC
89 mi away
Good Deal

$29,995

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Flame Red Clearcoat
Fuel type:
Diesel
Interior color:
Black
Transmission:
Automatic
Mileage:
23,921
Stock #:
P56554
VIN:
3C6UR5EL9PG556554
Flame Red Clearcoat 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2023 RAM 2500

Rebel Crew Cab 4WD

23,921 mi

North Charleston, SC
93 mi away
Good Deal

$59,638

Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Bright White Clearcoat
Fuel type:
Diesel
Interior color:
Diesel Gray/Black
Transmission:
6-Speed Automatic
Mileage:
101,055
Stock #:
26RM451A
VIN:
3C6UR5DL5MG578970
Bright White Clearcoat 2021 RAM 2500 Pickup Truck Four-Wheel Drive 6-Speed Automatic
Price drop

-$1,500

 

2021 RAM 2500

Big Horn Crew Cab 4WD

101,055 mi

Summerville, SC
85 mi away
Great Deal

$33,214

$31,714

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Delmonico Red Pearlcoat
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
66,455
Stock #:
26662A
VIN:
3C6TR5EJ4NG368080
Delmonico Red Pearlcoat 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Power Wagon Crew Cab 4WD

66,455 mi

Spartanburg, SC
87 mi away
Fair Deal
Manufacturer certified

$47,399

CarGurus Analysis:

2022 RAM 2500

4.8

  • With 3,899 currently listed for sale and an average price of $41,465, 33.3% of 2022 RAM 2500 listings on CarGurus are rated as good or great deals.

  • Favorably reviewed: Owners rated the 2022 RAM 2500 4.8 / 5 stars.

  • 78.4% of 2022 RAM 2500 listings on CarGurus are accident free.

Research summarized using AI

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
35,943
Stock #:
28855484
VIN:
3C6UR5CJ7NG231755
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2022 RAM 2500

Tradesman Crew Cab 4WD

35,943 mi

Store transfer to Columbia, SC
Price includes $249 shipping
Good Deal

$35,247

Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Go Mango
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
74,076
Stock #:
PC6889
VIN:
3C6TR5EJ7MG568921
Go Mango 2021 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2021 RAM 2500

Power Wagon Crew Cab 4WD

74,076 mi

Graniteville, SC
58 mi away
Fair Deal

$43,963

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
White
Fuel type:
Diesel
Interior color:
Gray
Transmission:
Automatic
Mileage:
137,308
Stock #:
2446
VIN:
3C6UR5JL2NG317818
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2022 RAM 2500

Big Horn Crew Cab LB 4WD

137,308 mi

Charlotte, NC
89 mi away
Good Deal

$29,995

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
8-Speed Automatic
Mileage:
117,085
Stock #:
D232156
VIN:
3C6UR5HJ0NG232156
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Tradesman Crew Cab LB 4WD

117,085 mi

Summerville, SC
86 mi away
Fair Deal

$25,024

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
19,553
Stock #:
61700
VIN:
3C6UR5DJ0PG512099
White 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2023 RAM 2500

Big Horn Crew Cab 4WD

19,553 mi

Aiken, SC
50 mi away
Great Deal

$39,900

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Olive Green Pearlcoat
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
29,724
Stock #:
G289944P
VIN:
3C6TR5EJ2NG289944
Olive Green Pearlcoat 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Power Wagon Crew Cab 4WD

29,724 mi

Home delivery from Deland, FL
Price includes $621 shipping
Good Deal

$49,508

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Flame Red Clearcoat
Fuel type:
Diesel
Interior color:
Black
Transmission:
Automatic
Mileage:
23,921
Stock #:
P56554
VIN:
3C6UR5EL9PG556554
Flame Red Clearcoat 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2023 RAM 2500

Rebel Crew Cab 4WD

23,921 mi

North Charleston, SC
93 mi away
Good Deal

$59,638

Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Gray (Granite Crystal Metallic Clearcoat)
Fuel type:
Diesel
Interior color:
Black
Transmission:
6-Speed Automatic
Mileage:
44,249
Stock #:
28332A
VIN:
3C6UR5DL3MG645548
Gray (Granite Crystal Metallic Clearcoat) 2021 RAM 2500 Pickup Truck Four-Wheel Drive 6-Speed Automatic
Stateline Chrysler Jeep Dodge

Sponsored by Stateline Chrysler Jeep Dodge

2021 RAM 2500

Big Horn Crew Cab 4WD

44,249 mi

Fort Mill, SC
72 mi away
Fair Deal

$47,637

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
8-Speed Automatic
Mileage:
89,771
Stock #:
13398
VIN:
3C6UR5HJ3NG130396
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

Sponsored Listing

2022 RAM 2500

Tradesman Crew Cab LB 4WD

89,771 mi

Monroe, NC
74 mi away
Good Deal

$28,668

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
White
Fuel type:
Diesel
Interior color:
Gray
Transmission:
Automatic
Mileage:
137,308
Stock #:
2446
VIN:
3C6UR5JL2NG317818
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2022 RAM 2500

Big Horn Crew Cab LB 4WD

137,308 mi

Charlotte, NC
89 mi away
Good Deal

$29,995

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Flame Red Clearcoat
Fuel type:
Diesel
Interior color:
Black
Transmission:
Automatic
Mileage:
23,921
Stock #:
P56554
VIN:
3C6UR5EL9PG556554
Flame Red Clearcoat 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2023 RAM 2500

Rebel Crew Cab 4WD

23,921 mi

North Charleston, SC
93 mi away
Good Deal

$59,638

Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Bright White Clearcoat
Fuel type:
Diesel
Interior color:
Diesel Gray/Black
Transmission:
6-Speed Automatic
Mileage:
101,055
Stock #:
26RM451A
VIN:
3C6UR5DL5MG578970
Bright White Clearcoat 2021 RAM 2500 Pickup Truck Four-Wheel Drive 6-Speed Automatic
Price drop

-$1,500

 

2021 RAM 2500

Big Horn Crew Cab 4WD

101,055 mi

Summerville, SC
85 mi away
Great Deal

$33,214

$31,714

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Delmonico Red Pearlcoat
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
66,455
Stock #:
26662A
VIN:
3C6TR5EJ4NG368080
Delmonico Red Pearlcoat 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Power Wagon Crew Cab 4WD

66,455 mi

Spartanburg, SC
87 mi away
Fair Deal
Manufacturer certified

$47,399

CarGurus Analysis:

2022 RAM 2500

4.8

  • With 3,899 currently listed for sale and an average price of $41,465, 33.3% of 2022 RAM 2500 listings on CarGurus are rated as good or great deals.

  • Favorably reviewed: Owners rated the 2022 RAM 2500 4.8 / 5 stars.

  • 78.4% of 2022 RAM 2500 listings on CarGurus are accident free.

Research summarized using AI

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
Automatic
Mileage:
35,943
Stock #:
28855484
VIN:
3C6UR5CJ7NG231755
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2022 RAM 2500

Tradesman Crew Cab 4WD

35,943 mi

Store transfer to Columbia, SC
Price includes $249 shipping
Good Deal

$35,247

Year:
2021
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Go Mango
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
74,076
Stock #:
PC6889
VIN:
3C6TR5EJ7MG568921
Go Mango 2021 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2021 RAM 2500

Power Wagon Crew Cab 4WD

74,076 mi

Graniteville, SC
58 mi away
Fair Deal

$43,963

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
White
Fuel type:
Diesel
Interior color:
Gray
Transmission:
Automatic
Mileage:
137,308
Stock #:
2446
VIN:
3C6UR5JL2NG317818
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

 

2022 RAM 2500

Big Horn Crew Cab LB 4WD

137,308 mi

Charlotte, NC
89 mi away
Good Deal

$29,995

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Gray
Transmission:
8-Speed Automatic
Mileage:
117,085
Stock #:
D232156
VIN:
3C6UR5HJ0NG232156
White 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Tradesman Crew Cab LB 4WD

117,085 mi

Summerville, SC
86 mi away
Fair Deal

$25,024

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
White
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
19,553
Stock #:
61700
VIN:
3C6UR5DJ0PG512099
White 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic
New arrival

 

2023 RAM 2500

Big Horn Crew Cab 4WD

19,553 mi

Aiken, SC
50 mi away
Great Deal

$39,900

Year:
2022
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
410 hp 6.4L V8
Exterior color:
Olive Green Pearlcoat
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
29,724
Stock #:
G289944P
VIN:
3C6TR5EJ2NG289944
Olive Green Pearlcoat 2022 RAM 2500 Pickup Truck Four-Wheel Drive 8-Speed Automatic

 

2022 RAM 2500

Power Wagon Crew Cab 4WD

29,724 mi

Home delivery from Deland, FL
Price includes $621 shipping
Good Deal

$49,508

Year:
2023
Make:
RAM
Model:
2500
Body type:
Pickup Truck
Doors:
4 doors
Drivetrain:
Four-Wheel Drive
Engine:
370 hp 6.7L I6 Diesel
Exterior color:
Flame Red Clearcoat
Fuel type:
Diesel
Interior color:
Black
Transmission:
Automatic
Mileage:
23,921
Stock #:
P56554
VIN:
3C6UR5EL9PG556554
Flame Red Clearcoat 2023 RAM 2500 Pickup Truck Four-Wheel Drive Automatic

Sponsored Listing

2023 RAM 2500

Rebel Crew Cab 4WD

23,921 mi

North Charleston, SC
93 mi away
Good Deal

$59,638

CarGurus Analysis: 2022 RAM 2500

Image Not Available

Summary

  • With 3,899 currently listed for sale and an average price of $41,465, 33.3% of 2022 RAM 2500 listings on CarGurus are rated as good or great deals.

  • Favorably reviewed: Owners rated the 2022 RAM 2500 4.8 / 5 stars.

  • 78.4% of 2022 RAM 2500 listings on CarGurus are accident free.

Why it stands out

The 2022 RAM 2500 stands out as a heavy-duty truck that blends serious capability with a more upscale feel than many buyers expect from the segment. In the fifth-generation Ram 2500, the redesign brought a stronger frame, new suspension, and a new transmission, helping it tow more than 35,000 pounds and carry nearly 8,000 pounds of payload. It also adopted a more aerodynamic look, LED lighting, and a cabin that borrowed heavily from the Ram 1500, with upgraded materials and available luxury amenities.

For 2022 specifically, the truck added Uconnect 5 and made blind-spot monitoring standard. That year also included available features such as a 360-degree camera, a 12-inch vertical touchscreen infotainment system with wireless Apple CarPlay and Android Auto accessibility, and a Harman Kardon 750-watt, 17-speaker audio system. The RamBox’s 115-volt outlet with up to 400 watts of power adds another practical touch, and the lineup still offered Regular-, Crew- and Mega-Cab configurations with standard and long beds depending on trim.

Buyers are likely to be drawn to the 2022 RAM 2500 for its combination of power, comfort, and technology. Owners also praise its towing ability, comfortable ride, and interior features. The main tradeoffs are that the truck can be expensive, and some drivers note engine and exhaust noise.

Other model years to consider

  • 2025 RAM 2500
    • Average price: $56,043
    • Good/great deal percentage: 33.9%
    • User rating: 5 / 5
    • Total listings: 6,483
  • 2020 RAM 2500
    • Average price: $37,858
    • Good/great deal percentage: 32.7%
    • User rating: 4.9 / 5
    • Total listings: 2,498
  • 2026 RAM 2500
    • Average price: $50,287
    • Good/great deal percentage: 33.3%
    • User rating: 5 / 5
    • Total listings: 3,783

Similar models to consider

  • 2022 Chevrolet Silverado 2500HD
    • Average price: $43,178
    • Good/great deal percentage: 33.0%
    • User rating: 4.8 / 5
    • Total listings: 3,160
  • 2022 GMC Sierra 2500HD
    • Average price: $50,069
    • Good/great deal percentage: 33.1%
    • User rating: 4.4 / 5
    • Total listings: 2,080
  • 2022 Nissan Titan
    • Average price: $27,664
    • Good/great deal percentage: 32.9%
    • User rating: 4.5 / 5
    • Total listings: 831

This analysis is based on CarGurus' proprietary market data from November 9, 2026, CarGurus experts' opinions, and generative AI.

*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.

A better way to discover your best deal

Let us help you find a car you’ll love.