Used 2022 Mercedes-Benz CLS 450 4MATIC for SaleNationwide
42 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,207
- Stock #:
- TD030931A
- VIN:
- W1K2J5KB3NA101445
New arrival
2022 Mercedes-Benz CLS
450 4MATIC
21,207 mi
West Palm Beach, FL
Good Deal
$48,469
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Blue
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,169
- Stock #:
- 60120A
- VIN:
- W1K2J5KB8NA103658
2022 Mercedes-Benz CLS
450 4MATIC
32,169 mi
Mesa, AZ
Good Deal
$43,974
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 46,316
- Stock #:
- 096186
- VIN:
- W1K2J5KB0NA096186
2022 Mercedes-Benz CLS
450 4MATIC
46,316 mi
Plano, TX
Fair Deal
$42,524
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 55,470
- Stock #:
- J1709
- VIN:
- W1K2J5KB7NA107782
2022 Mercedes-Benz CLS
450 4MATIC
55,470 mi
San Diego, CA
Fair Deal
$38,985
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 40,156
- Stock #:
- NA107242
- VIN:
- W1K2J5KB8NA107242
2022 Mercedes-Benz CLS
450 4MATIC
40,156 mi
Grapevine, TX
Great Deal
$39,282
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Sienna Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 9,327
- Stock #:
- U4956
- VIN:
- W1K2J5KB4NA104628
2022 Mercedes-Benz CLS
450 4MATIC
9,327 mi
Mamaroneck, NY
Great Deal
$46,665
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 28,623
- Stock #:
- 14437
- VIN:
- W1K2J5KB3NA100019
2022 Mercedes-Benz CLS
450 4MATIC
28,623 mi
Tigard, OR
Great Deal
$42,240
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 29,467
- Stock #:
- 5069578-1
- VIN:
- W1K2J5KB6NA108132
2022 Mercedes-Benz CLS
450 4MATIC
29,467 mi
Los Angeles, CA
Fair Deal
$47,060
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Manufackur Cote d'Azur Light Blue Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchito & Magma Grey Leather)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 10,662
- Stock #:
- 13458
- VIN:
- W1K2J5KB6NA102394
2022 Mercedes-Benz CLS
450 4MATIC
10,662 mi
Knoxville, TN
Good Deal
$53,349
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,715
- Stock #:
- B10047P
- VIN:
- W1K2J5KBXNA105301
2022 Mercedes-Benz CLS
450 4MATIC
38,715 mi
Ramsey, NJ
Great Deal
$39,006
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Macchiato/Magma Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 6,954
- Stock #:
- NA106395
- VIN:
- W1K2J5KB6NA106395
2022 Mercedes-Benz CLS
450 4MATIC
6,954 mi
Atlanta, GA
Fair Deal
$52,662
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,324
- Stock #:
- 205274P
- VIN:
- W1K2J5KB1NA104909
Price drop
-$1,000
2022 Mercedes-Benz CLS
450 4MATIC
42,324 mi
Norwalk, CA
Fair Deal
$42,113
$41,113
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,950
- Stock #:
- NA100714A
- VIN:
- W1K2J5KBXNA100714
2022 Mercedes-Benz CLS
450 4MATIC
32,950 mi
Greenwich, CT
Good Deal
$41,608
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Sienna Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 45,448
- Stock #:
- NA105198
- VIN:
- W1K2J5KBXNA105198
2022 Mercedes-Benz CLS
450 4MATIC
45,448 mi
City Of Industry, CA
Good Deal
$40,121
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,454
- Stock #:
- 839
- VIN:
- W1K2J5KB7NA107586
New arrival
2022 Mercedes-Benz CLS
450 4MATIC
48,454 mi
Modesto, CA
Fair Deal
$40,127
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 56,636
- Stock #:
- 098632C01
- VIN:
- W1K2J5KB7NA098632
2022 Mercedes-Benz CLS
450 4MATIC
56,636 mi
Streetsboro, OH
Fair Deal
$38,447
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,042
- Stock #:
- BW6641
- VIN:
- W1K2J5KB1NA104960
2022 Mercedes-Benz CLS
450 4MATIC
39,042 mi
Solon, OH
Fair Deal
$44,328
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,413
- Stock #:
- FT08939
- VIN:
- W1K2J5KB1NA095354
2022 Mercedes-Benz CLS
450 4MATIC
42,413 mi
Paterson, NJ
Fair Deal
$42,784
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,837
- Stock #:
- 10002P
- VIN:
- W1K2J5KBXNA099323
Price drop
-$1,409
2022 Mercedes-Benz CLS
450 4MATIC
34,837 mi
Bedford, OH
Great Deal
$43,360
$41,951
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 31,659
- Stock #:
- DTNA096235
- VIN:
- W1K2J5KB9NA096235
2022 Mercedes-Benz CLS
450 4MATIC
31,659 mi
Fairfax, VA
Fair Deal
$44,788
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 28,078
- Stock #:
- C4835
- VIN:
- W1K2J5KB5NA107439
2022 Mercedes-Benz CLS
450 4MATIC
28,078 mi
North Plainfield, NJ
Good Deal
$45,994
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,151
- Stock #:
- TNA105046
- VIN:
- W1K2J5KB9NA105046
2022 Mercedes-Benz CLS
450 4MATIC
30,151 mi
West Chester, OH
Good Deal
$45,875
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Graphite Grey Metallic)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,568
- Stock #:
- NA097540
- VIN:
- W1K2J5KB8NA097540
New arrival
2022 Mercedes-Benz CLS
450 4MATIC
25,568 mi
Nashville, TN
Good Deal
$45,990
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 18,662
- Stock #:
- 101463
- VIN:
- W1K2J5KB5NA101463
2022 Mercedes-Benz CLS
450 4MATIC
18,662 mi
Pawtucket, RI
Fair Deal
$51,794
3.0 Overall rating
Filter by rating
John S
Reviewed a 2022 Mercedes-Benz 450 4MATIC on Oct 15, 2025
It’s a little overpriced for a vehicle that is no longer in production
Is this review helpful?
FAQs
How much does the Mercedes-Benz CLS 450 4MATIC cost?
The average Mercedes-Benz CLS 450 4MATIC costs about $43,421.22. The average price has decreased by -6.1% since last year. The 170 for sale on CarGurus range from $21,794 to $65,758 in price.
How many Mercedes-Benz CLS 450 4MATIC vehicles have no reported accidents or damage?
135 out of 170 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz CLS 450 4MATIC?
Depending on the engine and options, the Mercedes-Benz CLS 450 4MATIC gets between 25 and 26 MPG (or EV battery range).
What fuel types are available?
Gasoline engines are available.
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