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Used 2022 Lexus RX for Sale near Denver, CO

103 results
Denver, CO
2022 Lexus RX 350 AWD AutoTrek - Littleton

2022 Lexus RX

350 AWD

48,527 miles

$37,989

Good Deal
Littleton, CO
13 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Black
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
48,527
Stock number:
PA330213
VIN:
2T2HZMDA5NC330213

Sponsored

2022 Lexus RX 350 F Sport AWD

2022 Lexus RX

350 F Sport AWD

50,900 miles

$41,999

Fair Deal
Parker, CO
19 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
22 MPG
Fuel type:
Gasoline
Interior color:
Circuit Red
Transmission:
8-Speed Automatic
Mileage:
50,900
Stock number:
NC333696
VIN:
2T2SZMDA3NC333696

Sponsored

2023 Lexus RX 350 F Sport Handling AWD

2023 Lexus RX

350 F Sport Handling AWD

19,249 miles

$51,911

Fair Deal
Englewood, CO
9 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Iridium
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Rioja Red
Transmission:
8-Speed Automatic
Mileage:
19,249
Stock number:
GT197145B
VIN:
2T2BAMCA2PC006282

Sponsored

2023 Lexus RX 350 Premium FWD

2023 Lexus RX

350 Premium FWD

35,006 miles

$41,987

Great Deal
Littleton, CO
13 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
25 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
35,006
Stock number:
PC003084
VIN:
2T2BAMBA3PC003084

2023 Lexus RX 350 F Sport Handling AWD

2023 Lexus RX

350 F Sport Handling AWD

15,293 miles

$50,490

Great Deal
Certified Pre-Owned
Greenwood Village, CO
10 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Nightfall Mica
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
15,293
Stock number:
PC009027
VIN:
2T2BAMCA1PC009027

2023 Lexus RX 350 F Sport Handling AWD

2023 Lexus RX

350 F Sport Handling AWD

33,324 miles

$48,194

Good Deal
Greenwood Village, CO
10 mi away
Year:
2023
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
All-Wheel Drive
Engine:
275 hp 2.4L I4
Exterior color:
Black (Caviar)
Combined gas mileage:
24 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
8-Speed Automatic
Mileage:
33,324
Stock number:
PC013601
VIN:
2T2BAMCA5PC013601

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

15,317 miles

$44,397

Fair Deal
Store transfer to Denver, CO
1,186 mi away • Price includes $1,399 shipping Price includes $1,399 shipping
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Red
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
15,317
Stock number:
28061702
VIN:
2T2HZMAA9NC260199

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

47,280 miles

$39,216

Good Deal
Certified Pre-Owned
Frederick, CO
26 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Green
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Transmission:
Automatic
Mileage:
47,280
Stock number:
SLF260166A
VIN:
2T2HZMAA4NC223562

Preparing for a close up...

Photos coming soon

2022 Lexus RX

350 FWD

39,142 miles

$37,000

Good Deal
Golden, CO
10 mi away
Year:
2022
Make:
Lexus
Model:
RX
Body type:
SUV / Crossover
Doors:
4 doors
Drivetrain:
Front-Wheel Drive
Engine:
295 hp 3.5L V6
Exterior color:
Atomic Silver
Combined gas mileage:
23 MPG
Fuel type:
Gasoline
Interior color:
Black
Transmission:
Automatic
Mileage:
39,142
Stock number:
NC232774
VIN:
2T2AZMAA7NC232774

Sponsored

  1. Home
  2. / Used Cars
  3. / Lexus RX
  4. / 2022
  5. / Colorado
  6. / Denver
Overview
Reviews
FAQs

CarGurus Analysis: 2022 Lexus RX

Picture of 2022 Lexus RX

Summary

  • With 2,526 currently listed for sale on CarGurus and an average price of $40,414.60, 35.6% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
  • Favorably reviewed: Owners rated the 2022 Lexus RX 4.6 / 5 stars and CarGurus experts gave it an 7.3 / 10.
  • 84.2% of 2022 RX models on CarGurus are accident free.
  • The 2022 Lexus RX combined a smooth ride quality with standard advanced safety features, solidifying its status as the brand's best-selling model despite its aging design.

Why it stands out

The 2022 Lexus RX stood out for its exceptional ride quality, ensuring a comfortable driving experience that many owners appreciated. It also included standard advanced safety features, reflecting Lexus's commitment to driver and passenger safety. Despite its dated design and some ergonomic considerations, the RX maintained strong sales figures, showcasing its enduring appeal in the luxury SUV market.

Other model years to consider

  • 2020 Lexus RX: This year offers $33,379.27 average price, 33% good/great deals, 4.8/5 user rating, 8.2/10 expert rating, 1,269 listings.
  • 2021 Lexus RX: This year offers $35,773.39 average price, 32% good/great deals, 4.7/5 user rating, 7.8/10 expert rating, 1,829 listings.
  • 2023 Lexus RX: This year offers $47,405.06 average price, 37% good/great deals, 4.6/5 user rating, 7.2/10 expert rating, 3,056 listings.

This analysis is based on CarGurus' proprietary market data from December 16, 2025, CarGurus experts' opinions, and generative AI.

4.6 Overall rating

(24 reviews)
Anonymous
5.0
Reviewed a 2022 Lexus RX on Feb 19, 2024

I just recently purchased a 2022 Lexus RX 350L(2 days actually). Still learning all the many features. Smooth, quiet ride. Great power response. Coming from a 2020 Mercedes GLE 350 I was a bit skeptical if It would measure up. It really does!!

Uday T
4.0
Reviewed a 2022 Lexus RX on Jun 06, 2023

Great car, drives smooth. Lacks pick up power for a V6

Anonymous
5.0
Reviewed a 2022 Lexus 350 AWD on Jun 06, 2023

No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.

Anonymous
4.0
Reviewed a 2022 Lexus 350 FWD on Feb 08, 2023

Car is wonderful except for the gas mileage. Pretty, nice size, comfortable, good safety features.

Anonymous
5.0
Reviewed a 2022 Lexus 350 FWD on Oct 03, 2022

An excellent car which is loaded with features and fun to drive. It is smooth and has a very quiet cabin. Also very luxurious materials in the cabin and fine leather seats,

2022 Lexus RX FAQs

How much does the 2022 Lexus RX cost in Denver, CO?

The average 2022 Lexus RX costs about $40,239.40. The average price has decreased by -5% since last year. The 103 for sale near Denver, CO on CarGurus, range from $28,290 to $56,996 in price.

Is the 2022 Lexus RX a good car?

CarGurus experts gave the 2022 Lexus RX an overall rating of 7.3/10 and 2022 Lexus RX owners have rated the vehicle a 4.6/5 stars on average. If a vehicle has both strong expert and owner reviews, you can feel confident in its quality. If either expert reviews, owner reviews, or both are spotty, you might want to do some research to figure out where the car falls short.

How many 2022 Lexus RX vehicles in Denver, CO have no reported accidents or damage?

95 out of 103 for sale near Denver, CO have no reported accidents or damage.

Is the 2022 Lexus RX safe?

CarGurus experts gave the 2022 Lexus RX a safety rating of 8/10.

What is the fuel economy of the 2022 Lexus RX?

Depending on the engine and options, the 2022 Lexus RX gets between 21 and 25 MPG (or MPGe).

What fuel types are available?

Gasoline engines are available.

  • 2025 Lexus RX in Denver CO

  • 2024 Lexus RX in Denver CO

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  • 2021 Lexus RX

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  • 2019 Lexus RX in Denver CO

  • Lexus RX 350 FWD

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