Used 2021 RAM 2500 for Sale near Spartanburg, SC

## Summary - With 3,767 currently listed for sale on CarGurus and an **average price of $41,595.00**, 34.2% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 RAM 2500 4.48 / 5 stars. - **78.9% of 2021 RAM 2500 models on CarGurus are accident free**. - The 2021 RAM 2500 is praised for its performance, safety features, and value for money, boasting impressive power and fuel efficiency, especially in its diesel variant. ## Why it stands out The 2021 RAM 2500 stands out in the heavy-duty truck segment thanks to its remarkable balance of capability and comfort. This model year introduced various enhancements, including solid performance and a range of powerful engine options, notably the 6.7-liter Cummins diesel. Owners particularly highlight its towing capacity and fuel efficiency, making it an excellent choice for those needing a reliable workhorse. While many appreciate the spacious and comfortable interior, some users have noted a desire for more modern technology features, like larger infotainment screens and cooled seats. Overall, the 2021 RAM 2500 effectively merges ruggedness with added luxury, making it appealing for both work and family use. ## Other model years to consider - **[2022 RAM 2500](https://www.cargurus.com/Cars/l-Used-2022-RAM-2500-c31581)** - Average price: $43,433.00 - Good/great deal percentage: 34.2% - User rating: 4.68 / 5 - Total listings: 3,887 - **[2020 RAM 2500](https://www.cargurus.com/Cars/l-Used-2020-RAM-2500-c29790)** - Average price: $39,617.00 - Good/great deal percentage: 34.3% - User rating: 4.74 / 5 - Total listings: 2,605 - **[2023 RAM 2500](https://www.cargurus.com/Cars/l-Used-2023-RAM-2500-c32547)** - Average price: $49,696.00 - Good/great deal percentage: 32.7% - User rating: 4.6 / 5 - Total listings: 7,454 This analysis is based on CarGurus' proprietary market data from March 2, 2026, CarGurus experts' opinions, and generative AI.