Used 2021 RAM 2500 for Sale near Missouri

## Summary - With 3,677 currently listed for sale and an **average price of $41,590.00**, 33.6% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 RAM 2500 4.48 / 5 stars. - **78.9% of 2021 RAM 2500 models on CarGurus are accident free**. ## Why it stands out The 2021 RAM 2500 is renowned for its powerful performance and strong safety features, making it a favorite among truck enthusiasts. With a robust towing capacity, especially when equipped with the optional diesel engine, it excels in both heavy-duty tasks and everyday driving. The interior, while spacious and comfortable, does receive mixed reviews regarding its modern amenities, with some users desiring larger screens and cooled seats. Nevertheless, its overall value for money, especially in the highly competitive heavy-duty truck market, is a significant draw for potential buyers. The RAM 2500 stands out due to its blend of capability, comfort, and an impressive range of trims that cater to diverse buyer needs. ## Other model years to consider - **[2020 RAM 2500](https://www.cargurus.com/Cars/l-Used-2020-RAM-2500-c29790)** - Average price: $39,489.00 - Good/great deal percentage: 33.0% - User rating: 4.74 / 5 - Total listings: 2,558 - **[2022 RAM 2500](https://www.cargurus.com/Cars/l-Used-2022-RAM-2500-c31581)** - Average price: $43,494.00 - Good/great deal percentage: 33.4% - User rating: 4.68 / 5 - Total listings: 3,803 - **[2023 RAM 2500](https://www.cargurus.com/Cars/l-Used-2023-RAM-2500-c32547)** - Average price: $49,538.00 - Good/great deal percentage: 33.4% - User rating: 4.6 / 5 - Total listings: 7,328 This analysis is based on CarGurus' proprietary market data from March 16, 2026, CarGurus experts' opinions, and generative AI.