Used 2021 Mercedes-Benz S-Class for Sale near Detroit, MI

## Summary - With 808 currently listed for sale on CarGurus and an **average price of $61,370.00**, 31.9% of 2021 Mercedes-Benz S-Class models for sale on CarGurus are rated as good or great deals. - **Favorably reviewed:** Owners rated the 2021 Mercedes-Benz S-Class 5 / 5 stars. - **83.4% of 2021 S-Class models on CarGurus are accident free**. - The 2021 Mercedes-Benz S-Class was redesigned to maintain its status as a technological showcase, featuring sophisticated infotainment systems and new powertrains. ## Why it stands out The 2021 Mercedes-Benz S-Class stands out in the luxury sedan segment with its remarkable blend of performance, advanced technology, and unrivaled comfort. This model year features a redesign that introduces more sophisticated infotainment options and improved powertrains, such as the 3.0-liter turbocharged inline-six in the S500 and the powerful 4.0-liter twin-turbo V8 in the S580. Notable updates include a drag coefficient (Cd) of 0.22, enhancing aerodynamics, and innovative features like rear-wheel steering, which improves maneuverability. While the car is not primarily a driver’s car, it balances comfortable riding dynamics with precise steering, making it appeal to buyers looking for both luxury and style. However, some users have mentioned issues with run-flat tires. ## Other model years to consider - **[2022 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2022-Mercedes-Benz-S-Class-c31858)** - Average price: $66,621.00 - Good/great deal percentage: 30.6% - User rating: 4.8 / 5 - Total listings: 1,042 - **[2015 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2015-Mercedes-Benz-S-Class-c24430)** - Average price: $25,902.00 - Good/great deal percentage: 29.3% - User rating: 4.88 / 5 - Total listings: 894 - **[2018 Mercedes-Benz S-Class](https://www.cargurus.com/Cars/l-Used-2018-Mercedes-Benz-S-Class-c27088)** - Average price: $35,246.00 - Good/great deal percentage: 34.0% - User rating: 4.76 / 5 - Total listings: 785 This analysis is based on CarGurus' proprietary market data from February 10, 2026, CarGurus experts' opinions, and generative AI.