Used 2021 Lexus RX for Sale nearMobile, AL
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 103,049
- Stock #:
- TGD21411A
- VIN:
- 2T2HZMAA3LC172780


Sponsored by Eastern Shore Toyota
2020 Lexus RX
350 FWD
103,049 mi
$29,472
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 30,893
- Stock #:
- L32593A
- VIN:
- 2T2AZMAA9NC236826

Sponsored Listing
2022 Lexus RX
350 FWD
30,893 mi
$45,306
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment w/Matte Bamboo Trim)
- Transmission:
- Automatic
- Mileage:
- 63,229
- Stock #:
- P7623A
- VIN:
- 2T2HZMAA1MC190373

-$1,380
Sponsored Listing
2021 Lexus RX
350 FWD
63,229 mi
$37,115
$35,735
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,229
- Stock #:
- 70111066
- VIN:
- 2T2HZMDAXNC322138

-$1,000
2022 Lexus RX
350 AWD
45,229 mi
$38,997
$37,997
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,728
- Stock #:
- L44497A
- VIN:
- 2T2HZMAA0MC216543

2021 Lexus RX
350 FWD
85,728 mi
$33,802
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 47,968
- Stock #:
- MC289582
- VIN:
- 2T2YZMDA7MC289582

2021 Lexus RX
350 F Sport Handling AWD
47,968 mi
$41,317
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 103,049
- Stock #:
- TGD21411A
- VIN:
- 2T2HZMAA3LC172780

2020 Lexus RX
350 FWD
103,049 mi
$29,472
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,338
- Stock #:
- NG1189
- VIN:
- 2T2AZMAA7MC182554

2021 Lexus RX
350 FWD
96,338 mi
$29,936
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- Automatic
- Mileage:
- 138,000
- Stock #:
- 12738
- VIN:
- 2T2HZMAA4LC165191

2020 Lexus RX
350 FWD
138,000 mi
$24,398
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment w/Matte Bamboo Trim)
- Transmission:
- Automatic
- Mileage:
- 63,229
- Stock #:
- P7623A
- VIN:
- 2T2HZMAA1MC190373

-$1,380
2021 Lexus RX
350 FWD
63,229 mi
$37,115
$35,735
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Scored Aluminum Trim
- Transmission:
- Automatic
- Mileage:
- 40,965
- Stock #:
- P7591A
- VIN:
- 2T2YZMDA6NC353452

-$1,012
2022 Lexus RX
350 F Sport Handling AWD
40,965 mi
$45,320
$44,308
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,646
- Stock #:
- 235219
- VIN:
- 2T2HZMAA7NC235219

2022 Lexus RX
350 FWD
23,646 mi
$42,596
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 40,301
- Stock #:
- 913641
- VIN:
- 2T2HZMDAXMC258486

2021 Lexus RX
350 AWD
40,301 mi
$41,015
CarGurus Analysis:
2021 Lexus RX
With 96 currently listed for sale near Mobile, AL and an average price of $33,395.00, 79.2% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
100.0% of 2021 RX models on CarGurus are accident free.
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 57,565
- Stock #:
- 180543
- VIN:
- 2T2HZMAA7LC180543

2020 Lexus RX
350 FWD
57,565 mi
$34,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 71,450
- Stock #:
- TMC188796
- VIN:
- 2T2AZMAA6MC188796

2021 Lexus RX
350 FWD
71,450 mi
$33,898
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch w/Matte Walnut Trim
- Transmission:
- Automatic
- Mileage:
- 54,790
- Stock #:
- B26263A
- VIN:
- 2T2HZMAA8MC210764

2021 Lexus RX
350 FWD
54,790 mi
$35,640
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 54,596
- Stock #:
- 171094
- VIN:
- 2T2AZMAA1LC171094

2020 Lexus RX
350 FWD
54,596 mi
$33,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 39,718
- Stock #:
- 28822128
- VIN:
- 2T2HZMAA5MC211287

2021 Lexus RX
350 FWD
39,718 mi
$39,147
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch w/Matte Walnut Trim
- Transmission:
- Automatic
- Mileage:
- 122,000
- Stock #:
- 209267
- VIN:
- 2T2HZMAA0MC209267

2021 Lexus RX
350 FWD
122,000 mi
$28,410
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,788
- Stock #:
- L479210A
- VIN:
- JTJHZKEA6M2019164

2021 Lexus RX
350L FWD
64,788 mi
$35,707
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 30,893
- Stock #:
- L32593A
- VIN:
- 2T2AZMAA9NC236826

2022 Lexus RX
350 FWD
30,893 mi
$45,306
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,677
- Stock #:
- 161094
- VIN:
- 2T2HZMAA8LC161094

2020 Lexus RX
350 FWD
49,677 mi
$35,418
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,728
- Stock #:
- L44497A
- VIN:
- 2T2HZMAA0MC216543

Sponsored Listing
2021 Lexus RX
350 FWD
85,728 mi
$33,802
CarGurus Analysis: 2021 Lexus RX
overall

Summary
With 96 currently listed for sale near Mobile, AL and an average price of $33,395.00, 79.2% of 2021 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX 4.92 / 5 stars and CarGurus experts gave it a 7.83 / 10.
100.0% of 2021 RX models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX continues to make a strong case for itself as one of America’s favorite luxury SUVs. For this model year, the body and mechanics are mostly unchanged, but it still stands out for comfortable accommodations, plenty of creature comforts, and Lexus’ long-standing reputation for reliability. It also brings a few tech upgrades for 2021, including new standard safety systems.
What makes the 2021 Lexus RX appealing is the way it balances comfort and value. Its ride quality is a clear strength, and the cabin is designed to be comfortable for everyday use. At the same time, it remains an excellent value for money in the luxury SUV class. The tradeoff is that performance is fairly pedestrian, and the technology can be unintuitive, so buyers who prioritize quick acceleration or a more seamless interface may find it less satisfying.
Other model years to consider
- Average price: $49,948.00
- Good/great deal percentage: 71.5%
- User rating: 5 / 5
- Total listings: 158
- Average price: $30,111.00
- Good/great deal percentage: 67.3%
- User rating: 4.88 / 5
- Total listings: 98
- Average price: $29,445.00
- Good/great deal percentage: 67.0%
- User rating: 5 / 5
- Total listings: 91
This analysis is based on CarGurus' proprietary market data from August 25, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Archie C
Reviewed a 2021 Lexus RX on Oct 14, 2024
Very reliable stylish looking drives well. Good suspension. Fun to drive
Mike R
Reviewed a 2021 Lexus RX on Oct 9, 2025
Love the car, smooth power delivery and a solid platform. A few minor cosmetics and a set of Michelin tires and it's perfect with 27k miles.
Ann W
Reviewed a 2021 Lexus RX on Feb 22, 2023
This car is beautiful and drives so smooth.
2021 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury FWD | $54,050 |
| 350 F Sport FWD | $48,700 |
| 350L FWD | $48,050 |
| 350L AWD | $49,450 |
| 350 F Sport AWD | $50,100 |
| 350 F Sport Handling AWD | $52,500 |
| 350 AWD | $46,620 |
| 350 FWD | $45,220 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX prices has changed over time.
See more price trends2021 Lexus RX Pricing Analysis: Mobile, AL Market Report
Pricing by Nearby Locations
Market Area: Mobile, AL
Key Insights
- Highest Prices in Pensacola: The market in Pensacola, FL ($36,845) shows the highest average price, likely due to higher demand and lower inventory.
- Lowest Prices in New Orleans: New Orleans, LA ($31,777) offers the lowest average price, indicating a more price-sensitive market or higher inventory levels.
- Inventory Variation: Markets like Meridian, MS (104 listings) have a larger inventory, which may contribute to more competitive pricing compared to areas with fewer listings.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Pensacola, FL | 98 | $36,845 |
| Biloxi, MS | 95 | $36,690 |
| Atmore, AL | 101 | $33,444 |
| Meridian, MS | 104 | $34,985 |
| Fort Walton Beach, FL | 99 | $36,845 |
| Slidell, LA | 92 | $32,596 |
| New Orleans, LA | 89 | $31,777 |
Pricing by Trim Packages
Key Insights
- FWD vs. AWD Demand: The 350 FWD (193 listings) is the most common trim, indicating a strong preference for front-wheel drive in the region.
- Premium Pricing for AWD Trims: The 350L Luxury AWD ($55,450 MSRP) is the highest priced trim, reflecting the demand for luxury features and all-wheel drive capability.
- Value in Base Trims: The 350 FWD ($45,220 MSRP) serves as a competitive entry point, appealing to budget-conscious buyers while still offering desirable features.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 350 FWD | 193 | $45,220 | FWD | 3.5L 295 hp V6 |
| 350 AWD | 107 | $46,620 | AWD | 3.5L 295 hp V6 |
| 350 F Sport AWD | 45 | $50,100 | AWD | 3.5L 295 hp V6 |
| 350 F Sport Handling AWD | 35 | $52,500 | AWD | 3.5L 295 hp V6 |
| 350L AWD | 17 | $49,450 | AWD | 3.5L 290 hp V6 |
| 350L FWD | 22 | $48,050 | FWD | 3.5L 290 hp V6 |
| 350 F Sport FWD | 17 | $48,700 | FWD | 3.5L 295 hp V6 |
| 350L Luxury AWD | 2 | $55,450 | AWD | 3.5L 290 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2026 Lexus RX is priced at $58,978, reflecting a 14.9% increase over its MSRP, indicating strong demand for the latest model.
- Significant Depreciation for Older Models: The 2016 Lexus RX shows a steep decline, priced at $19,000, which is -54.6% from its original MSRP, highlighting rapid depreciation for older vehicles.
- Best Value in Recent Models: The 2022 Lexus RX is priced at $41,995, only -8.5% below MSRP, making it a compelling option for buyers seeking a balance of price and modern features.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $51,225 | $58,978 | +14.9% |
| 2025 | $48,975 | $52,605 | +7.0% |
| 2024 | $48,600 | $49,068 | +1.0% |
| 2023 | $47,800 | $52,448 | +9.8% |
| 2022 | $45,920 | $41,995 | -8.5% |
| 2020 | $44,150 | $28,473 | -35.5% |
| 2019 | $43,820 | $29,445 | -32.9% |
| 2017 | $43,220 | $22,900 | -47.1% |
| 2016 | $41,900 | $19,000 | -54.6% |
| 2015 | $40,970 | $15,123 | -63.1% |
| 2014 | $39,760 | $16,115 | -59.5% |
These recommendations are based on CarGurus' proprietary market data from August 27, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2021 Lexus RX cost?
| Metric | Value |
|---|---|
| Current Average Price | $36,049 |
| Year-Round Low | $35,273.76 |
| Year-Round High | $36,806.64 |
| Average Price a Year Ago | $36,682 |
| Change vs. Last Year | −1.73% |
Prices have softened 1.73% compared to this time last year, making it a favorable time to shop this model year.
There are 1,495 listings available, which suggests you have room to compare options before you commit.
If you find a listing below $35,273.76, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 Lexus RX a good car?
Yes — the 2021 Lexus RX earns a 4.92/5 user rating and a 7.83/10 expert rating. The standout strength is Cost effectiveness at 9/10.
Owners consistently praise its reliability, luxurious features, and smooth driving experience, and they also call out its comfort and handling. That lines up with the RX’s use case as a comfortable, everyday luxury SUV that puts ride quality and cabin comfort ahead of flashier performance. The main trade-offs are fairly pedestrian performance and technology that can feel unintuitive.
With 30.0% of listings marked as good or great deals, the market still gives you some room to find value if you shop carefully.
Is the 2021 Lexus RX reliable?
Owners rate it 4.92/5, a strong signal of long-term satisfaction.
Owner feedback points to reliability, and the model is also described as having Lexus’ long-standing reputation for reliability. The expert evaluation reinforces that theme by calling the RX a vehicle with tried-and-true reliability and a tradition of reliability that extends to the model. Lexus also includes a first scheduled maintenance visit on the house.
For used buyers, the main long-term ownership risk is less about basic dependability and more about whether the specific vehicle has been maintained well and used gently.
What should I look for when buying a used 2021 Lexus RX?
At 74.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially if the listing price looks unusually attractive. Focus on overall condition, signs of prior bodywork, and whether the cabin and technology still feel consistent with the mileage and asking price.
Key things to evaluate:
- Trim level: The RX lineup includes the RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid. The base RX gets standard 18-inch aluminum wheels, LED lighting, rear privacy glass, and a well-equipped interior with NuLuxe-trimmed seats, power-adjustable front seats, and a power tilt/telescoping steering wheel. The F Sport Appearance package adds 20-inch F Sport wheels, black outer mirrors, F Sport badging, a unique fascia, and other sport-themed touches, while the extended-body RXL variants add a third row.
- Powertrain: The RX, RXL, and RX F-Sport use a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque paired with an eight-speed automatic. The RX Hybrid and RXL Hybrid use a 3.5-liter V6 with three electric motors for 308 hp and an e-CVT, and they come standard with AWD.
- Safety package: Every RX comes with Lexus Safety System+ 2.0, which includes a pre-collision system with forward-collision warning, automatic emergency braking, pedestrian detection, cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. Standard equipment also includes a rearview camera, 10 airbags, enhanced vehicle stability control, and blind-spot monitoring with rear cross-traffic alert.
- Infotainment: Standard tech includes an 8-inch infotainment touchscreen, voice recognition, Bluetooth, Apple CarPlay, Android Auto, Amazon Alexa, satellite radio, HD Radio, a WiFi hot spot, six USB ports, and a nine-speaker sound system. A 12.3-inch screen, navigation, wireless charging, and upgraded audio systems are available, but wireless Apple CarPlay or Android Auto is not offered.
- Fuel efficiency: The front-wheel-drive RX 350 is rated at 20 mpg city, 27 mpg highway, and 23 mpg combined. AWD or the RXL lowers combined efficiency by 1 mpg, and the RXL with AWD gets 21 mpg combined. The RX Hybrid and RXL Hybrid return 29 or 31 mpg city and 28 mpg highway, depending on the model.
Which 2021 Lexus RX trim should I buy?
The 2021 Lexus RX is offered in 5 trim levels: RX, RX F Sport, RXL, RX Hybrid, and RXL Hybrid.
Here's the short version:
- RX: This is the standard starting point and the best-value choice if you want the core RX experience without paying for extra body length or hybrid hardware. You still get the comfort-focused cabin, strong standard safety tech, and the everyday usability that define the model.
- RX F Sport: Choose this if you want the most driver-focused gas model in the lineup. It adds a sportier look and feel, and the available F Sport Handling package brings adaptive variable suspension, heated and ventilated front seats, and a heated steering wheel.
- RXL: Pick this if you want the extended body and the added flexibility of a third row. It suits you best if passenger space matters more than keeping the shortest, simplest RX configuration.
- RX Hybrid: This is the efficiency-minded choice if you want the RX formula with better fuel economy and standard AWD. It makes the most sense if you value lower fuel use and smooth power delivery over maximum simplicity.
- RXL Hybrid: Choose this if you want the third-row body style and hybrid efficiency together. It is the most specialized option for shoppers who need extra seating and want to keep fuel economy strong.
The safety suite is standard across the lineup, but the longer RXL and RXL Hybrid were not tested by IIHS.
Is now a good time to buy a used 2021 Lexus RX?
This is a moderate, selective buyer’s market, so you can shop with some leverage if you stay disciplined.
- Deal availability: 30.0% of listings are priced as good or great deals.
- Inventory: There are 1,495 listings available.
- Price trend: Prices have softened 1.73% compared with last year.
- Clean inventory: 74.6% of listings are accident-free.
If you find a listing below $35,273.76, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 Lexus RX's resale value?
The current average of $36,049 sits slightly below last year's $36,682.
That kind of softening can work against a future seller if the market stays well supplied, because buyers have more room to negotiate. At the same time, the RX’s strong reputation for comfort, reliability, and value helps support demand. If you buy well and keep the vehicle in clean condition, you’re starting from a relatively stable position for resale.
Vehicles with strong owner satisfaction ratings, like this model year's 4.92/5, tend to retain buyer demand, which supports resale value over time.
Is the 2021 Lexus RX safe?
The 2021 Lexus RX earns IIHS Top Safety Pick recognition, and the tested NHTSA models received four-star overall ratings with five-star side-impact ratings.
It earns a 8/10 safety score from our experts.
Every RX comes with Lexus Safety System+ 2.0, which includes a pre-collision system with forward-collision warning, automatic emergency braking, pedestrian detection, cyclist detection, automatic high beams, adaptive cruise control, lane-departure warning with steering assist, lane-keep assist, lane-trace assist, and road sign assist. Standard safety equipment also includes a rearview camera, 10 airbags, enhanced vehicle stability control, and blind-spot monitoring with rear cross-traffic alert.
One caveat is that the longer RXL and RXL Hybrid were not tested by IIHS, so you should pay extra attention to condition and equipment if you’re shopping those versions.
Should I buy a 2021 Lexus RX or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 30.0% of listings are priced as good or great deals.
- At 74.6% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
- Price trend: Prices have softened 1.73% compared with last year.
- Owners rate it 4.92/5 — a strong satisfaction signal.
- The 2021 adds new standard safety systems while keeping the RX’s comfort-first formula intact.
Consider the 2020 if:
- At $33,600, the 2020 costs less than the current year's $36,049 average.
- It emphasizes comfort, quietness, and everyday usability.
Consider the 2022 if:
- At $39,724, the 2022 costs more than the current year's $36,049 average.
- It brings minimal changes, including new colors and a standalone fog lamps option.
The bottom line: If you want the best balance of price, comfort, and strong owner satisfaction, the 2021 is the smart default. If your budget is tighter, the 2020 can save you money while staying close to the same core experience. If you want a newer model-year sticker and don’t mind paying more, the 2022 is the cleaner alternative.
These recommendations are based on CarGurus' proprietary market data from August 28, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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