Used 2021 Lexus RX 350 AWD for Sale Nationwide
143 results
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 50,658
- Stock #:
- C1454B
- VIN:
- 2T2JZMDA7MC306298
New arrival
2021 Lexus RX
350 AWD
50,658 mi
Provo, UT
Fair Deal
$38,673
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Brown (Tan)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 63,727
- Stock #:
- FHXB036722B
- VIN:
- 2T2HZMDAXMC282478
New arrival
2021 Lexus RX
350 AWD
63,727 mi
Sandusky, OH
Fair Deal
$37,187
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 55,000
- Stock #:
- 264149A
- VIN:
- 2T2HZMDA1MC262913
2021 Lexus RX
350 AWD
55,000 mi
Melbourne, FL
Great Deal
$33,588
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 57,359
- Stock #:
- GU340
- VIN:
- 2T2HZMDA8MC271706
2021 Lexus RX
350 AWD
57,359 mi
Albany, NY
Good Deal
$34,277
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 76,194
- Stock #:
- 729531
- VIN:
- 2T2HZMDA4MC263988
2021 Lexus RX
350 AWD
76,194 mi
Englewood, CO
Good Deal
$33,880
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Ash
- Transmission:
- 8-Speed Automatic
- Mileage:
- 51,751
- Stock #:
- P4430
- VIN:
- 2T2HZMDA8MC297500
2021 Lexus RX
350 AWD
51,751 mi
Newberg, OR
Good Deal
$37,427
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 53,634
- Stock #:
- 6B261P
- VIN:
- JTJHZMDA4M2052984
2021 Lexus RX
350 AWD
53,634 mi
Lansing, MI
Fair Deal
$37,752
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 47,056
- Stock #:
- 24771
- VIN:
- JTJHZMDA4M2052015
2021 Lexus RX
350 AWD
47,056 mi
Arroyo Grande, CA
Good Deal
$36,580
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 35,438
- Stock #:
- FBA0077
- VIN:
- 2T2HZMDA6MC266343
2021 Lexus RX
350 AWD
35,438 mi
Ashland, VA
Good Deal
$39,189
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,983
- Stock #:
- B20898A
- VIN:
- 2T2AZMDAXMC260286
2021 Lexus RX
350 AWD
62,983 mi
Vancouver, WA
Fair Deal
$37,088
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 60,002
- Stock #:
- MC300764
- VIN:
- 2T2HZMDA4MC300764
2021 Lexus RX
350 AWD
60,002 mi
Hardeeville, SC
Good Deal
$37,590
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 35,161
- Stock #:
- 24818
- VIN:
- 2T2AZMDA6MC282883
2021 Lexus RX
350 AWD
35,161 mi
Arroyo Grande, CA
Fair Deal
$40,080
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,915
- Stock #:
- CU21090T
- VIN:
- 2T2HZMDA0MC304360
2021 Lexus RX
350 AWD
41,915 mi
Queens Village, NY
Good Deal
$34,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 53,990
- Stock #:
- TMC301120
- VIN:
- 2T2HZMDA9MC301120
2021 Lexus RX
350 AWD
53,990 mi
Columbia, SC
Good Deal
$37,253
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- MATADOR RED MICA
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- BLACK W/MATTE WALNUT TRIM
- Transmission:
- Automatic
- Mileage:
- 75,292
- Stock #:
- 264407A
- VIN:
- 2T2HZMDA2MC277971
2021 Lexus RX
350 AWD
75,292 mi
Kaukauna, WI
Good Deal
$35,105
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- 8-Speed Automatic
- Mileage:
- 81,923
- Stock #:
- 7807
- VIN:
- 2T2HZMDA1MC297807
New arrival
2021 Lexus RX
350 AWD
81,923 mi
Pittsburgh, PA
Great Deal
$28,900
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 66,816
- Stock #:
- FLU8077
- VIN:
- 2T2HZMDA1MC287133
2021 Lexus RX
350 AWD
66,816 mi
Lansdale, PA
Great Deal
$33,475
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 102,423
- Stock #:
- 265398
- VIN:
- 2T2HZMDA4MC265398
2021 Lexus RX
350 AWD
102,423 mi
Long Beach, CA
Good Deal
$28,129
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 60,544
- Stock #:
- P4218A
- VIN:
- 2T2HZMDA2MC300441
New arrival
2021 Lexus RX
350 AWD
60,544 mi
Willoughby, OH
Fair Deal
$35,875
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 94,088
- Stock #:
- L261114A
- VIN:
- 2T2HZMDA3MC261732
2021 Lexus RX
350 AWD
94,088 mi
Wayzata, MN
Fair Deal
$31,899
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 39,396
- Stock #:
- Y5976T
- VIN:
- 2T2AZMDA2MC297798
2021 Lexus RX
350 AWD
39,396 mi
Columbus, OH
Good Deal
$36,398
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 71,355
- Stock #:
- 2533C
- VIN:
- 2T2HZMDA4MC289278
2021 Lexus RX
350 AWD
71,355 mi
Levittown, NY
Great Deal
$30,945
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,983
- Stock #:
- BY70411
- VIN:
- 2T2HZMDA7MC296273
2021 Lexus RX
350 AWD
25,983 mi
Flushing, NY
Fair Deal
$37,770
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,116
- Stock #:
- K0415
- VIN:
- 2T2AZMDA8MC262165
New arrival
2021 Lexus RX
350 AWD
65,116 mi
Draper, UT
Good Deal
$34,494
5.0 Overall rating
Filter by rating
Michael B
Reviewed a 2021 Lexus 350 AWD on Sep 18, 2025
Premium package with LTA, SCS, heating/ventilation seating, pre-collision detection, etc.
Is this review helpful?
FAQs
How much does the Lexus RX 350 AWD cost?
The average Lexus RX 350 AWD costs about $36,302.43. The average price has increased by 2.5% since last year. The 2073 for sale on CarGurus range from $2,750 to $66,405 in price.
How many Lexus RX 350 AWD vehicles have no reported accidents or damage?
1310 out of 2073 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX 350 AWD?
Depending on the engine and options, the Lexus RX 350 AWD gets between 19 and 24 MPG (or EV battery range).
What fuel types are available?
Gasoline engines are available.
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