Used 2022 Lexus RX 350 AWD for SaleNationwide
119 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 38,347
- Stock #:
- COBTNC358391B
- VIN:
- 2T2JZMDA2NC358391
2022 Lexus RX
350 AWD
38,347 mi
Tampa, FL
Great Deal
$36,588
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 16,959
- Stock #:
- 16751
- VIN:
- 2T2HZMDA2NC333778
2022 Lexus RX
350 AWD
16,959 mi
Green Brook, NJ
Fair Deal
$43,828
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl - 085
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black - 24
- Transmission:
- Automatic
- Mileage:
- 43,059
- Stock #:
- NC326076
- VIN:
- 2T2AZMDAXNC326076
2022 Lexus RX
350 AWD
43,059 mi
Springfield, NJ
Fair Deal
$38,720
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,516
- Stock #:
- KBB10108O
- VIN:
- 2T2AZMDA7NC345569
2022 Lexus RX
350 AWD
46,516 mi
Fontana, CA
Great Deal
$33,374
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,645
- Stock #:
- VW20898B
- VIN:
- 2T2HZMDA2NC318830
2022 Lexus RX
350 AWD
62,645 mi
Ramsey, NJ
Fair Deal
$36,113
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 57,344
- Stock #:
- NC362644
- VIN:
- 2T2AZMDA3NC362644
Price drop
-$997
2022 Lexus RX
350 AWD
57,344 mi
Mechanicsburg, PA
Good Deal
$36,487
$35,490
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,536
- Stock #:
- NC317559
- VIN:
- 2T2AZMDA7NC317559
2022 Lexus RX
350 AWD
58,536 mi
Richardson, TX
Good Deal
$35,779
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- NIGHTFALL MICA
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- GLAZED CARAMEL W/MATTE WALNUT
- Transmission:
- Automatic
- Mileage:
- 62,890
- Stock #:
- 265049A
- VIN:
- 2T2HZMDA8NC312966
2022 Lexus RX
350 AWD
62,890 mi
Middleton, WI
Fair Deal
$39,267
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 51,526
- Stock #:
- NC333782VP
- VIN:
- 2T2HZMDA4NC333782
2022 Lexus RX
350 AWD
51,526 mi
Johnston, IA
Good Deal
$38,900
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 84,218
- Stock #:
- L321017A
- VIN:
- 2T2HZMDA9NC350349
2022 Lexus RX
350 AWD
84,218 mi
Saint Paul, MN
Good Deal
$33,500
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,709
- Stock #:
- T469922A
- VIN:
- 2T2HZMDA2NC323591
2022 Lexus RX
350 AWD
23,709 mi
Las Vegas, NV
Good Deal
$41,299
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 68,972
- Stock #:
- LK2740221A
- VIN:
- 2T2HZMDA7NC318337
Price drop
-$1,588
2022 Lexus RX
350 AWD
68,972 mi
Lakeville, MN
Good Deal
$36,587
$35,349
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Leather
- Transmission:
- Automatic
- Mileage:
- 52,885
- Stock #:
- 262113A
- VIN:
- 2T2HZMDA2NC350354
Price drop
-$824
2022 Lexus RX
350 AWD
52,885 mi
St Louis, MO
Good Deal
$40,153
$39,329
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,284
- Stock #:
- UT7081
- VIN:
- 2T2HZMDA7NC314241
2022 Lexus RX
350 AWD
59,284 mi
Long Island City, NY
Fair Deal
$35,165
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,528
- Stock #:
- H679275A
- VIN:
- 2T2HZMDA4NC310051
Price drop
-$1,636
2022 Lexus RX
350 AWD
73,528 mi
Dayton, OH
Great Deal
$35,433
$34,245
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black/Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,229
- Stock #:
- P19968
- VIN:
- 2T2HZMDA1NC320245
Price drop
-$1,182
2022 Lexus RX
350 AWD
45,229 mi
Tulsa, OK
Great Deal
$38,607
$37,425
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Leather
- Transmission:
- Automatic
- Mileage:
- 60,233
- Stock #:
- 3328
- VIN:
- 2T2HZMDA3NC313328
2022 Lexus RX
350 AWD
60,233 mi
Portland, OR
Good Deal
$37,045
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 32,997
- Stock #:
- 239P26
- VIN:
- 2T2AZMDA3NC338926
Price drop
-$1,307
2022 Lexus RX
350 AWD
32,997 mi
Lynnwood, WA
Great Deal
$38,995
$37,888
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,194
- Stock #:
- MP00075
- VIN:
- 2T2AZMDA5NC340953
2022 Lexus RX
350 AWD
48,194 mi
Austin, TX
Good Deal
$37,125
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Matte Walnut Trim
- Transmission:
- Automatic
- Mileage:
- 62,071
- Stock #:
- LT60675A
- VIN:
- 2T2HZMDA2NC308847
New arrival
2022 Lexus RX
350 AWD
62,071 mi
Saint Albans, WV
Good Deal
$35,457
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 32,039
- Stock #:
- 71326172T
- VIN:
- 2T2HZMDA8NC326172
2022 Lexus RX
350 AWD
32,039 mi
Saginaw, MI
Fair Deal
$43,065
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 45,098
- Stock #:
- 4442A
- VIN:
- 2T2AZMDA3NC349313
Price drop
-$1,400
2022 Lexus RX
350 AWD
45,098 mi
Burlingame, CA
Good Deal
$39,985
$38,585
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,524
- Stock #:
- N1Y0004
- VIN:
- 2T2AZMDA6NC316306
2022 Lexus RX
350 AWD
45,524 mi
Fairfax, VA
Good Deal
$38,589
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 65,179
- Stock #:
- B26781T
- VIN:
- JTJHZMDA1N2058310
Price drop
-$1,000
2022 Lexus RX
350 AWD
65,179 mi
Bridgeport, CT
Good Deal
$36,628
$35,628
5.0 Overall rating
Filter by rating
Anonymous
Reviewed a 2022 Lexus 350 AWD on Jun 6, 2023
No unneeded frills but lots of quality of life items. Love the backup camera and surround view, easily the best one out of all the cars we test drove (GMC, Buick, Ford, Nissan). Suspension is solid, corners well, and plenty of power.
Is this review helpful?
FAQs
How much does the Lexus RX 350 AWD cost?
The average Lexus RX 350 AWD costs about $38,506.94. The average price has decreased by -4.8% since last year. The 2109 for sale on CarGurus range from $1,499 to $80,198 in price.
How many Lexus RX 350 AWD vehicles have no reported accidents or damage?
1309 out of 2109 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX 350 AWD?
Depending on the engine and options, the Lexus RX 350 AWD gets between 19 and 24 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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