Used 2021 Honda Odyssey for Sale nearIndianapolis, IN

How much does the 2021 Honda Odyssey cost?

Prices have softened 6.41% compared to this time last year, making it a favorable time to shop this model year.

There are 1,427 listings available, which suggests you have a solid amount of inventory to compare.

Is the 2021 Honda Odyssey a good car?

Yes — the 2021 Honda Odyssey earns a 4.8/5 user rating and a 7.8/10 expert rating. The model scores 9/10 across Look and feel and Safety.

Owners consistently praise its space, safety features, family-friendly conveniences, and good drivability. The overview also points to its roomy cabin, practical utility, and polished styling as reasons it works well for daily family use.

The trade-offs are that it is not available as a hybrid and is not as luxurious as some rivals, and all-wheel drive is not available. Even so, it remains a strong fit if you want a well-rounded family vehicle that prioritizes passenger room and usability.

Good and great deals account for 35.3% of listings, which means there are still worthwhile opportunities in the market.

Is the 2021 Honda Odyssey reliable?

Owners rate it 4.8/5, a strong signal of long-term satisfaction. Owners also describe it as a dependable family vehicle with space and safety features they can count on, along with helpful family-focused conveniences.

The expert evaluation reinforces that dependability with smooth, effortless power and a drivetrain that feels well suited to everyday use. The cost-effectiveness notes also point to strong utility and practicality for the money.

Honda also includes a first-year HondaLink Security subscription with automatic collision notification, SOS emergency calling, enhanced roadside assistance, and a personal data wipe function. For used buyers, the main long-term ownership risk is making sure the vehicle has been maintained well, especially given the added wear that comes with family use.

What should I look for when buying a used 2021 Honda Odyssey?

At 64.5% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report and then prioritize a careful inspection of bodywork, safety systems, and interior wear. Because this model is often used for family duty, condition can vary a lot from one listing to the next, so pay close attention to signs of heavy use.

Key things to evaluate:

• Trim level: LX is the base trim, and EX adds the 8-inch touchscreen with Apple CarPlay, Android Auto, satellite radio, HD Radio, text-messaging support, basic HondaLink connectivity, and the Cabin Control smartphone app. Touring adds navigation, HondaLink subscription plans, WiFi capability, CabinWatch, and CabinTalk, while Elite adds an 11-speaker premium sound system, multi-zone listening options, and wireless smartphone charging.
• Powertrain: The Odyssey uses a 3.5-liter V6 with a ten-speed automatic transmission and front-wheel drive. It makes 280 horsepower, includes Normal, Sport, Econ, and Snow driving modes, and uses variable cylinder management to help conserve fuel.
• Safety package: Honda Sensing is standard on LX and includes low-speed follow capability for adaptive cruise control, pedestrian braking, road-sign recognition, and a dashboard menu button for ADAS settings. Blind-spot warning with rear cross-traffic warning still requires at least EX trim.
• Infotainment: EX and above get an 8-inch touchscreen with Apple CarPlay and Android Auto. Touring adds navigation, WiFi capability, CabinWatch, and CabinTalk, while Elite adds wireless smartphone charging and a premium audio system.
• Fuel efficiency: The EPA says it should get 22 mpg in combined driving, and testing returned 21.8 mpg.

Which 2021 Honda Odyssey trim should I buy?

The 2021 Honda Odyssey is offered in 5 trim levels: LX, EX, EX-L, Touring, and Elite.

Here's the short version:

• LX: This is the value-focused starting point, and it already includes Honda Sensing, LED headlights with automatic high-beam assist, and the core safety tech that makes the Odyssey appealing from the outset.
• EX: This is the best-value trim for many shoppers because it adds the 8-inch touchscreen, Apple CarPlay, Android Auto, and the Cabin Control smartphone app, making it the first trim that feels fully modern inside.
• EX-L: Choose this if you want a more upscale family hauler without jumping all the way to the higher trims; it builds on the EX formula with more comfort-oriented equipment.
• Touring: This is the right pick if you want the most family-friendly tech, including navigation, WiFi capability, CabinWatch, CabinTalk, and the rear-seat entertainment system.
• Elite: Pick this if you want the most premium Odyssey, with perforated leather upholstery, ambient lighting, an 11-speaker sound system, multi-zone listening, and wireless smartphone charging.

Blind-spot warning with rear cross-traffic warning still requires at least EX trim.

Is now a good time to buy a used 2021 Honda Odyssey?

This looks like a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.

• Deal availability: 35.3% of listings are priced as good or great deals.
• Inventory: There are 1,427 listings available.
• Price trend: Prices have softened 6.41% compared with last year.
• Clean inventory: 64.5% of listings are accident-free.

If you find a listing below $25,872, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2021 Honda Odyssey's resale value?

The current average of $25,896 sits slightly below last year's $27,669.

That decline suggests the market has softened, which can help you buy more affordably now. For a future seller, it also means resale value may be more sensitive to condition, mileage, and trim choice than it was a year ago.

Well-kept examples should still hold appeal because the Odyssey has strong family utility and broad shopper demand. Vehicles with strong owner satisfaction ratings, like this model year's 4.8/5, tend to retain buyer demand, which supports resale value over time.

Is the 2021 Honda Odyssey safe?

The 2021 Honda Odyssey should once again earn a Top Safety Pick recommendation from the Insurance Institute for Highway Safety (IIHS), and it earns five-star ratings in all NHTSA tests except rollover resistance, where it earns a four-star rating.

It earns a 9/10 safety score from our experts.

Honda Sensing is standard on base LX trim and includes adaptive cruise control with low-speed follow, pedestrian braking, road-sign recognition, and a dashboard menu button for quick ADAS access. If you want blind-spot warning with rear cross-traffic warning, you still need to move up to EX trim.

The main caveat is that the ADAS can feel a little less smooth than you might want in traffic, and the lane-departure warning uses steering-wheel movement rather than vibration. The rollover result is also the one NHTSA area that falls short of the Odyssey’s otherwise strong crash-test performance.

Should I buy a 2021 Honda Odyssey or consider a different year?

If you're weighing the 2021 against nearby model years, here's how to think about it:

Choose the 2021 if:

• 35.3% of listings are priced as good or great deals.
• At 64.5% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have softened 6.41% compared with last year.
• Owners rate it 4.8/5 — a strong satisfaction signal.
• The 2021 brings improved safety, upgraded technology, and refreshed styling.

Consider the 2022 if:

• At $27,887, the 2022 costs more than the current year's $25,896 average.
• It keeps the Odyssey’s enjoyable driving character while adding no major changes.

The bottom line: If you want the better value, the 2021 is the smarter buy because prices have eased and the model still brings strong safety, space, and family-friendly tech. If you are willing to pay more for a newer model year, the 2022 is the cleaner alternative, but it does not appear to bring a major upgrade that changes the value equation.

How does the 2021 Honda Odyssey compare to the 2021 Chrysler Pacifica?

Expert Pros & Cons (per CarGurus review team)

2021 Honda Odyssey:

• Pros: Spacious, Stylish design, Spacious third row.
• Cons: Not available as a hybrid, Not as luxurious as its competitors, All-wheel drive not available.

2021 Chrysler Pacifica:

• Pros: Stylish design, Spacious third row, Impressive technology.
• Cons: Plug-in hybrid can't be ordered with all-wheel drive.

Our experts score the 2021 Honda Odyssey 7.8/10 and the 2021 Chrysler Pacifica 8.7/10. The Pacifica gets the higher expert score and brings more impressive technology, while the Odyssey counters with strong space and a stylish design of its own. If you care most about luxury and tech, the Pacifica has the edge; if you want a practical family hauler with a spacious third row, the Odyssey still makes a strong case.

Read our full side-by-side expert comparison here.

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.