Used 2021 GMC Sierra 2500HD for Sale nearDenver, CO
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 34,855
- Stock #:
- P356958
- VIN:
- 1GT49LE7XNF356958
Sponsored by Mike Maroone Chevrolet Buick GMC Longmont
2022 GMC Sierra 2500HD
Pro Crew Cab 4WD
34,855 mi
$43,822
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Met)
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 88,215
- Stock #:
- NF359392
- VIN:
- 1GT49REY7NF359392
-$1,330
Sponsored Listing
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
88,215 mi
$49,328
$47,998
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 127,061
- Stock #:
- 55550
- VIN:
- 1GT59NE79NF106921
Sponsored Listing
2022 GMC Sierra 2500HD
SLT Double Cab 4WD
127,061 mi
$35,990
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 104,736
- Stock #:
- T103437A
- VIN:
- 1GT49REY6NF103437
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
104,736 mi
$47,799
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Met)
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 88,215
- Stock #:
- NF359392
- VIN:
- 1GT49REY7NF359392
-$1,330
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
88,215 mi
$49,328
$47,998
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 6-Speed Automatic
- Mileage:
- 83,000
- Stock #:
- 25576B
- VIN:
- 1GT29ME74NF218300
2022 GMC Sierra 2500HD
SLE Double Cab 4WD
83,000 mi
$34,950
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 34,855
- Stock #:
- P356958
- VIN:
- 1GT49LE7XNF356958
2022 GMC Sierra 2500HD
Pro Crew Cab 4WD
34,855 mi
$43,822
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 6-Speed Automatic
- Mileage:
- 87,466
- Stock #:
- 260359C
- VIN:
- 1GT29ME70MF214212
2021 GMC Sierra 2500HD
SLE Double Cab 4WD
87,466 mi
$32,978
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Blue
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 78,205
- Stock #:
- T18316
- VIN:
- 1GT29ME75MF230633
2021 GMC Sierra 2500HD
SLE Double Cab 4WD
78,205 mi
$32,500
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 97,493
- Stock #:
- 2025-526
- VIN:
- 1GT49ME77MF311402
2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
97,493 mi
$33,863
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White
- Fuel type:
- Biodiesel
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- Automatic
- Mileage:
- 113,803
- Stock #:
- 4767
- VIN:
- 1GT49REY1LF166989
-$1,000
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
113,803 mi
$47,393
$46,393
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Cardinal Red
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 95,019
- Stock #:
- JV179854
- VIN:
- 1GT49NE76NF179854
2022 GMC Sierra 2500HD
SLT Crew Cab 4WD
95,019 mi
$40,720
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 119,822
- Stock #:
- STWT120960
- VIN:
- 1GT49PEY5LF120960
2020 GMC Sierra 2500HD
AT4 Crew Cab 4WD
119,822 mi
$46,099
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 186 currently listed for sale near Denver, CO and an average price of $43,605.00, 26.9% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
72.6% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and comfort features, making it a strong competitor in the heavy-duty truck market.
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Exterior color:
- Black
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 73,208
- Stock #:
- 26A039
- VIN:
- 1GT49PEY8LF279830
2020 GMC Sierra 2500HD
AT4 Crew Cab 4WD
73,208 mi
$50,990
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Onyx Black
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 99,766
- Stock #:
- 260406A
- VIN:
- 1GT19REYXLF341937
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
99,766 mi
$49,992
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Fuel type:
- Biodiesel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 60,081
- Stock #:
- 115976
- VIN:
- 1GT49REY8NF115976
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
60,081 mi
$55,739
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Onyx Black
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 90,485
- Stock #:
- X317399
- VIN:
- 1GT19PEYXNF317399
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
90,485 mi
$50,785
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Exterior color:
- Blue
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 90,828
- Stock #:
- 28400351
- VIN:
- 1GT49REY6LF163411
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
90,828 mi
$52,797
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 2 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 167,007
- Stock #:
- T18508
- VIN:
- 1GT09LE71NF226419
2022 GMC Sierra 2500HD
Pro Regular Cab LB 4WD
167,007 mi
$22,987
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 91,529
- Stock #:
- P289516
- VIN:
- 1GT49PEY4NF289516
-$2,467
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
91,529 mi
$53,755
$52,183
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Gasoline
- Interior color:
- Dark Walnut/Slate
- Transmission:
- 6-Speed Automatic
- Mileage:
- 50,084
- Stock #:
- A3304
- VIN:
- 1GT59ME77LF206300
2020 GMC Sierra 2500HD
SLE Double Cab 4WD
50,084 mi
$40,752
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 39,193
- Stock #:
- TCRTMF274102
- VIN:
- 1GT49REY9MF274102
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
39,193 mi
$59,499
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black, Forge Perforated Leather Seat Trim
- Transmission:
- Automatic
- Mileage:
- 58,638
- Stock #:
- TNF149862
- VIN:
- 1GT49REY9NF149862
Sponsored Listing
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
58,638 mi
$61,964
CarGurus Analysis: 2021 GMC Sierra 2500HD
Summary
With 186 currently listed for sale near Denver, CO and an average price of $43,605.00, 26.9% of 2021 GMC Sierras 2500HD for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
72.6% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and comfort features, making it a strong competitor in the heavy-duty truck market.
Why it stands out
The 2021 GMC Sierra 2500HD distinguishes itself with its blend of rugged capability and upscale features, appealing to buyers who need a heavy-duty truck without sacrificing comfort. This model year offers a range of advanced technology and comfort amenities, aligning with GMC's "Professional Grade" branding. The Sierra 2500HD is equipped with a powerful engine lineup, including options for both gas and diesel, ensuring it can handle demanding tasks while providing a smooth ride. Additionally, the truck's spacious interior and high-quality materials set it apart from competitors, making it a popular choice for both personal and fleet use. However, potential buyers should be aware of some common issues reported in earlier generations, particularly with electrical systems and infotainment glitches.
Other model years to consider
- Average price: $75,522.00
- Good/great deal percentage: 22.2%
- User rating: 5 / 5
- Total listings: 415
- Average price: $50,692.00
- Good/great deal percentage: 26.5%
- User rating: 4.86 / 5
- Total listings: 136
- Average price: $35,476.00
- Good/great deal percentage: 28.4%
- User rating: 5 / 5
- Total listings: 116
This analysis is based on CarGurus' proprietary market data from July 14, 2026, CarGurus experts' opinions, and generative AI.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB RWD | $36,200 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLE Crew Cab 4WD | $48,200 |
| SLT Crew Cab 4WD | $56,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis: Denver, CO Market Report
Pricing by Nearby Locations
Market Area: Denver, CO
Key Insights
- Highest Prices in Pueblo: The average price in Pueblo, CO ($56,681) is significantly higher than other nearby cities, indicating strong demand or limited supply.
- Lowest Prices in Laramie: Conversely, Laramie, WY ($20,695) offers the lowest average price, suggesting a more price-sensitive market or higher inventory turnover.
- Price Stability in Castle Rock and Longmont: Both Castle Rock ($43,374) and Longmont ($43,387) show similar pricing, reflecting stable market conditions in these areas.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Pueblo, CO | 176 | $56,681 |
| Colorado Springs, CO | 180 | $48,990 |
| Fort Collins, CO | 167 | $42,263 |
| Castle Rock, CO | 187 | $43,374 |
| Longmont, CO | 181 | $43,387 |
| Cheyenne, WY | 167 | $36,845 |
| Grand Junction, CO | 155 | $53,387 |
| Laramie, WY | 159 | $20,695 |
Pricing Analysis by Model Year
Key Insights
- Significant New-Car Premium: The 2026 GMC Sierra 2500HD is priced at $82,648, which is approximately 76.5% above its MSRP, indicating strong demand for the latest model.
- Depreciation Trends: The 2019 model shows a notable depreciation of -7.5%, while older models like the 2015 and 2014 have depreciated significantly more, at -20.7% and -18.4%, respectively.
- Best Value Years: The 2022 model is priced at $50,283, only -1.4% below MSRP, making it a strong candidate for buyers looking for value without sacrificing recency.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 | $47,000 | $82,648 | +76.5% |
| 2025 | $46,300 | $75,313 | +62.8% |
| 2024 | $45,400 | $69,659 | +53.3% |
| 2023 | $42,200 | $49,331 | +16.9% |
| 2022 | $36,200 | $50,283 | -1.4% |
| 2020 | $35,800 | $50,025 | +39.7% |
| 2019 | $38,200 | $35,476 | -7.5% |
| 2018 | $35,000 | $38,355 | +9.8% |
| 2017 | $34,190 | $29,989 | -12.3% |
| 2016 | $33,535 | $35,249 | +5.1% |
| 2015 | $33,195 | $26,309 | -20.7% |
| 2014 | $31,310 | $25,562 | -18.4% |
These recommendations are based on CarGurus' proprietary market data from July 16, 2026, CarGurus experts' opinions, and generative AI.
FAQs
How much does the 2021 GMC Sierra 2500HD cost in Denver, CO?
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Relevant articles
2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.
2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.
Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
