Used 2016 Mercedes-Benz S-Class for Sale near Indiana

Compare 2016 Mercedes-Benz S-Class Trims

The S-Class lineup offers a range of luxury options from the budget-friendly S 550 to the high-performance S 63 AMG, catering to various preferences and needs.

• Starting at $23,696
• Best MPG/MPGe: 17 city / 26 hwy
• Most Popular: S 550 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

Missing data displayed as "—".

Trim Deep Dives

S 550 — "Who It's For"

The S 550 is the pick for shoppers who want a luxury sedan experience without the higher price of the AMG models. It offers a great balance of features and performance.

• Avg. market price: $23,696 (updated weekly)
• MPG/MPGe: 17 city / 26 hwy
• Inventory: 517 listings
• View S 550 listings

S 550 4MATIC — "Who It's For"

The S 550 4MATIC is the pick for shoppers who want all-wheel drive capability without paying for the higher-performance AMG models. It's the most popular trim for good reason.

• Avg. market price: $26,071 (updated weekly)
• MPG/MPGe: 16 city / 26 hwy
• Inventory: 580 listings
• View S 550 4MATIC listings

S 63 AMG — "Who It's For"

The S 63 AMG is the pick for shoppers who want a sportier driving experience with luxury features. It combines performance with the comfort expected from the S-Class.

• Avg. market price: $42,939 (updated weekly)
• MPG/MPGe: 15 city / 23 hwy
• Inventory: 142 listings — lower availability; may limit negotiating room
• View S 63 AMG listings

S 600 — "Who It's For"

The S 600 is the pick for shoppers who want a powerful V12 engine and a luxurious ride. It offers a standard luxury experience with ample power.

• Avg. market price: $29,537 (updated weekly)
• MPG/MPGe: 14 city / 21 hwy
• Inventory: 29 listings — lower availability; may limit negotiating room
• View S 600 listings

Maybach S 600 — "Who It's For"

The Maybach S 600 is the pick for shoppers who want the ultimate in luxury and exclusivity. It offers a high-end experience with advanced features.

• Avg. market price: $51,753 (updated weekly)
• MPG/MPGe: 13 city / 20 hwy
• Inventory: 19 listings — lower availability; may limit negotiating room
• View Maybach S 600 listings

S 65 AMG — "Who It's For"

The S 65 AMG is the pick for shoppers who want a fully loaded performance sedan with a powerful V12 engine. It combines luxury with extreme performance.

• Avg. market price: $67,920 (updated weekly)
• MPG/MPGe: 13 city / 20 hwy
• Inventory: 29 listings — lower availability; may limit negotiating room
• View S 65 AMG listings

Trim Recommendations

Most Popular — S 550 4MATIC

With 580 active listings, the S 550 4MATIC is the clear volume leader in the lineup.

Browse S 550 4MATIC listings

Best Budget Option — S 550

At $23,696 avg market price — below the lineup median of $36,238 — it's the most accessible entry point.

Browse S 550 listings

Best for Fuel Economy — S 550

The S 550 is the most fuel-efficient trim, offering 17/26 MPG/MPGe.

Browse S 550 listings

These recommendations are based on CarGurus' proprietary market data from November 12, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2016 Mercedes-Benz S-Class cost?

Prices have softened 10.83% compared to this time last year, making it a favorable time to shop this model year.

There are 954 listings available, which gives you a solid pool to compare prices and equipment.

Is the 2016 Mercedes-Benz S-Class a good car?

The 2016 Mercedes-Benz S-Class is a compelling choice if you want a flagship luxury sedan that emphasizes comfort, technology, and performance, though it comes with the usual premium-car tradeoffs. Its user rating is 3.9/5, which suggests many shoppers find it rewarding but not without caveats.

Drivers commonly praise its luxurious feel, advanced amenities, and strong handling. Review feedback also points to good value for money and performance that compares favorably with competitors. In practical terms, that lines up well with the S-Class’s role as a large luxury sedan for buyers who want a richly equipped daily driver or long-distance cruiser.

With 34.6% of listings marked as good or great deals, the market offers a meaningful number of opportunities if you shop carefully.

Is the 2016 Mercedes-Benz S-Class reliable?

The 2016 Mercedes-Benz S-Class stands out as a flagship luxury sedan that blends advanced technology with fine craftsmanship. Review feedback suggests owners appreciate its luxurious feel and strong performance, while also noting that maintenance costs and electronic components can become challenging over time.

That means you should think of it as a sophisticated used luxury car that can be satisfying to own, but one where upkeep history matters a lot. For long-term ownership, the biggest risk is not just mileage — it is whether the car has been maintained consistently and repaired properly when electronics or other premium systems needed attention.

What should I look for when buying a used 2016 Mercedes-Benz S-Class?

At 59.1% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report and confirm whether any reported damage was cosmetic or structural. After that, prioritize a thorough pre-purchase inspection, with extra attention to electronics, comfort features, and any signs of deferred maintenance. Because this is a high-end luxury sedan, condition and service records matter more than simply finding the lowest price.

Is now a good time to buy a used 2016 Mercedes-Benz S-Class?

This looks like a moderate, selective buyer’s market, so you have room to shop carefully rather than rush.

• Deal availability: 34.6% of listings are priced as good or great deals.
• Inventory: There are 954 listings available.
• Price trend: Prices have softened 10.83% compared with last year.
• Clean inventory: 59.1% of listings are accident-free.

If you find a listing below $28,183, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2016 Mercedes-Benz S-Class's resale value?

The current average of $28,240 sits slightly below last year's $31,668.

That price movement suggests the model has already absorbed some depreciation, which can help you as a buyer but may limit upside if you plan to resell soon. For a future seller, the key takeaway is that well-kept examples with strong history and desirable equipment should hold up better than average, while higher-mileage or poorly documented cars may be harder to price aggressively.

Should I buy a 2016 Mercedes-Benz S-Class or consider a different year?

If you're weighing the 2016 against nearby model years, here's how to think about it:

Choose the 2016 if:

• 34.6% of listings are priced as good or great deals.
• At 59.1% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have softened 10.83% compared with last year.

The bottom line: The 2016 is a strong choice if you want a luxury flagship with a softer used-car price and you are willing to be selective about condition and history. If you are especially price-sensitive, it is worth comparing nearby model years to see whether a cleaner or better-equipped example offers a better overall value for your budget.

How does the 2016 Mercedes-Benz S-Class compare to the 2016 BMW 7 Series?

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.