Used 2016 Mercedes-Benz E-Class for Sale nearIndianapolis, IN

Compare 2016 Mercedes-Benz E-Class Trims in Indianapolis, IN

The 2016 E-Class offers a range of trims from budget-friendly options to luxury models, all featuring impressive performance and technology.

• Starting at $14,745
• Best MPG/MPGe: 20 city / 29 hwy
• Most Popular: E 350 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

Missing data displayed as "—".

Trim Deep Dives

E 350 — "Who It's For"

The E 350 is the pick for shoppers who want a luxury sedan experience without the higher price of AWD options.

• Avg. market price: $18,297 (updated weekly)
• MPG/MPGe: 20 city / 29 hwy
• Inventory: 22 listings
• View E 350 listings

E 350 4MATIC — "Who It's For"

The E 350 4MATIC is the pick for shoppers who want all-wheel drive without paying a premium. It's also the most popular trim in the lineup.

• Avg. market price: $14,745 (updated weekly)
• MPG/MPGe: 20 city / 28 hwy
• Inventory: 130 listings — widest selection in the lineup
• View E 350 4MATIC listings

E 400 Coupe 4MATIC — "Who It's For"

The E 400 Coupe 4MATIC is the pick for shoppers who want a sporty coupe with luxury features without stepping up to the higher trims.

• Avg. market price: $18,297 (updated weekly)
• MPG/MPGe: 20 city / 28 hwy
• Inventory: 6 listings — lower availability; may limit negotiating room
• View E 400 Coupe 4MATIC listings

E 350 4MATIC Wagon — "Who It's For"

The E 350 4MATIC Wagon is the pick for shoppers who want the versatility of a wagon with all-wheel drive without the higher price of luxury models.

• Avg. market price: $16,500 (updated weekly)
• MPG/MPGe: 20 city / 27 hwy
• Inventory: 5 listings — lower availability; may limit negotiating room
• View E 350 4MATIC Wagon listings

E 400 Cabriolet — "Who It's For"

The E 400 Cabriolet is the pick for shoppers who want a stylish convertible with luxury features without going for the highest trims.

• Avg. market price: $22,747 (updated weekly)
• MPG/MPGe: 20 city / 29 hwy
• Inventory: 16 listings — lower availability; may limit negotiating room
• View E 400 Cabriolet listings

E 550 Cabriolet — "Who It's For"

The E 550 Cabriolet is the pick for shoppers who want a powerful V8 performance in a stylish convertible without stepping up to the AMG model.

• Avg. market price: $18,297 (updated weekly)
• Inventory: 7 listings — lower availability; may limit negotiating room
• View E 550 Cabriolet listings

AMG E 63 S Sedan 4MATIC — "Who It's For"

The AMG E 63 S Sedan 4MATIC is the pick for shoppers who want high-performance luxury without compromise.

• Avg. market price: $18,297 (updated weekly)
• MPG/MPGe: 15 city / 22 hwy
• Inventory: 24 listings
• View AMG E 63 S Sedan 4MATIC listings

Trim Recommendations

Most Popular — E 350 4MATIC

With 130 active listings, the E 350 4MATIC is the clear volume leader in the lineup.

Browse E 350 4MATIC listings

Best Budget Option — E 350 4MATIC

At $14,745 avg market price — below the lineup median of $18,297 — it's the most accessible entry point.

Browse E 350 4MATIC listings

Best for Fuel Economy — E 350

The E 350 offers the best fuel economy in the lineup at 20/29 MPG.

Browse E 350 listings

These recommendations are based on CarGurus' proprietary market data from October 8, 2026, CarGurus experts' opinions, and generative AI.

How much does the 2016 Mercedes-Benz E-Class cost?

Prices have held steady compared to this time last year, signaling a stable and predictable market for this model year.

There are 1,023 listings available, which gives you a solid pool of options to compare by condition, mileage, and equipment.

Is the 2016 Mercedes-Benz E-Class a good car?

Yes — the 4.64/5 user rating points to strong owner satisfaction. Owners repeatedly praise its classic styling, comfortable drive, and the performance of the 6-cylinder engine, and the model’s upscale cabin and generous standard equipment make it appealing if you want a luxury sedan that feels polished and well equipped. If you’re shopping for a used luxury car that balances comfort, technology, and everyday refinement, this model year fits that brief well. With 35.3% of listings marked as good or great deals, you also have a meaningful chance to find a competitively priced example.

Is the 2016 Mercedes-Benz E-Class reliable?

Owners rate it 4.64/5, a strong signal of long-term satisfaction.

Owner feedback highlights reliability, and the summary also points to a comfortable, trouble-free ownership experience for many drivers. That said, you should still expect the usual used-luxury-car risk profile, where maintenance history and condition matter a lot more than the badge alone. For long-term ownership, a well-documented example is the safer bet.

What should I look for when buying a used 2016 Mercedes-Benz E-Class?

At 55.1% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report so you can confirm accident records, title status, and service history before you go any further. After that, prioritize a pre-purchase inspection, with extra attention on brakes, infotainment behavior, and overall mechanical condition. Because this is a luxury model, you’ll want to focus on how well the car has been maintained rather than just how it looks in photos.

Is now a good time to buy a used 2016 Mercedes-Benz E-Class?

This is a moderate buyer’s market, so you can be selective without expecting deep bargain-bin pricing.

• Deal availability: 35.3% of listings are priced as good or great deals.
• Inventory: There are 1,023 listings available.
• Price trend: Prices have held steady compared with last year.
• Clean inventory: 55.1% of listings are accident-free.

If you find a listing below $15,004, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2016 Mercedes-Benz E-Class's resale value?

The current average of $15,465 sits slightly below last year's $15,607.

That small decline suggests the market has been fairly stable, which can help future sellers because it reduces the risk of sharp value swings. If you buy well and keep the car in strong condition, you’re more likely to preserve value than if you overpay for a rough example. The model’s luxury appeal and broad shopper interest should continue to support demand, especially for clean, well-maintained listings.

Vehicles with strong owner satisfaction ratings, like this model year's 4.64/5, tend to retain buyer demand, which supports resale value over time.

Should I buy a 2016 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2016 against nearby model years, here's how to think about it:

Choose the 2016 if:

• 35.3% of listings are priced as good or great deals.
• At 55.1% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have held steady compared with last year.
• Owners rate it 4.64/5 — a strong satisfaction signal.

The bottom line:

The 2016 is a strong choice if you want a well-equipped luxury sedan with solid owner approval and a stable price profile. If you’re focused on value, this year makes sense when you find a clean, well-documented example at the lower end of the market; if you want to shop more aggressively on price, you may want to compare nearby years and prioritize the best-maintained car rather than the newest badge.

These recommendations are based on CarGurus' proprietary market data from October 6, 2026, CarGurus experts' opinions, and generative AI.