Diagnostic test said misfire on 2,4,&6. Replaced spark plugs & wires. Then test said misfire on 6 so replaced coil packs. Still gives p0306 code, misfire on 6.

At least at this point it's isolated to cyl #6. Have you checked the injector? connections? I know you stated that you replaced a lot of the ignition system, but have you verified spark on #6?

Yes have done all, do you think it could have jumped time?

I would think there would be a lot more codes if it jumped time. Have you performed a compression test?

Gonna do that in the morning

Since your misfire went away in 2,,4cyl. But stayed in 6,I'd recheck my plug ,could be a gap or dirt in between electrode