Electrical Issue

I have an 04 Durango Limited. I recently started having an issue with the electrical
system. I have no power to the radio or climate controls. However  when plugged in,
the heat is at full blast and i am unabnle to turn it off. there is no illumination of any
of the controls either. When this started happeing, power locks no longer work from
the key fob. I have to lock and unlock manually. The overhead lights, and sunroof
controls work but the compass, the garage door opener buttons, and other buttons
do not. The keyfob is no longer working at all. I read a few posts about having the
instrument cluster replaced and i have, but did not fix, Can anyone give me any
ideas as to where to even begin? Ive checked fuses multiple times and even
replaced any that i had questioned. Ive checked wiring as much as i possibly could,
and make sure there were no bare wires. Im frustrated, ive been fairly lucky
considering the reviews i have read from  similar models. 2004 Durango Limited
183,000 mi.